| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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193 genes differentially expressed following the sitosterol-7332 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AGMAT | agmatine ureohydrolase (agmatinase) |
| AIPL1 | aryl hydrocarbon receptor interacting protein-like 1 |
| ALK | anaplastic lymphoma receptor tyrosine kinase |
| ALS2CL | ALS2 C-terminal like |
| APOE | apolipoprotein E |
| ATP6V0A4 | ATPase, H+ transporting, lysosomal V0 subunit a4 |
| BRF1 | BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit |
| CACNA1H | calcium channel, voltage-dependent, T type, alpha 1H subunit |
| CD74 | CD74 molecule, major histocompatibility complex, class II invariant chain |
| CD8A | CD8a molecule |
| CDHR2 | cadherin-related family member 2 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 |
| CHST5 | carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 5 |
| CLCN6 | chloride channel, voltage-sensitive 6 |
| COL6A1 | collagen, type VI, alpha 1 |
| CPA2 | carboxypeptidase A2 (pancreatic) |
| CST6 | cystatin E/M |
| DHRS12 | dehydrogenase/reductase (SDR family) member 12 |
| DOCK5 | dedicator of cytokinesis 5 |
| EEA1 | early endosome antigen 1 |
| EHBP1L1 | EH domain binding protein 1-like 1 |
| ELP6 | elongator acetyltransferase complex subunit 6 |
| FANCA | Fanconi anemia, complementation group A |
| FGFR1 | fibroblast growth factor receptor 1 |
| FGL1 | fibrinogen-like 1 |
| FH | fumarate hydratase |
| FSCN1 | fascin actin-bundling protein 1 |
| FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) |
| GM2A | GM2 ganglioside activator |
| GNPTAB | N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits |
| GPLD1 | glycosylphosphatidylinositol specific phospholipase D1 |
| GPR19 | G protein-coupled receptor 19 |
| GRM8 | glutamate receptor, metabotropic 8 |
| GSTA3 | glutathione S-transferase alpha 3 |
| HIST1H2BN | histone cluster 1, H2bn |
| HIST1H4E | histone cluster 1, H4e |
| HNF4A | hepatocyte nuclear factor 4, alpha |
| HR | hair growth associated |
| IFNAR1 | interferon (alpha, beta and omega) receptor 1 |
| KBTBD11 | kelch repeat and BTB (POZ) domain containing 11 |
| LMF2 | lipase maturation factor 2 |
| LTBP4 | latent transforming growth factor beta binding protein 4 |
| MAP1A | microtubule-associated protein 1A |
| MOCS1 | molybdenum cofactor synthesis 1 |
| MTA1 | metastasis associated 1 |
| NAB1 | NGFI-A binding protein 1 (EGR1 binding protein 1) |
| NEUROD4 | neuronal differentiation 4 |
| NF1 | neurofibromin 1 |
| NOS1AP | nitric oxide synthase 1 (neuronal) adaptor protein |
| ORAI2 | ORAI calcium release-activated calcium modulator 2 |
| OVOL2 | ovo-like zinc finger 2 |
| PCGF3 | polycomb group ring finger 3 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 |
| PDPR | pyruvate dehydrogenase phosphatase regulatory subunit |
| PER3 | period circadian clock 3 |
| PHEX | phosphate regulating endopeptidase homolog, X-linked |
| PLAC1 | placenta-specific 1 |
| PLIN2 | perilipin 2 |
| PMEL | premelanosome protein |
| PPAP2B | phosphatidic acid phosphatase type 2B |
| PRDX2 | peroxiredoxin 2 |
| PTPN21 | protein tyrosine phosphatase, non-receptor type 21 |
| PXN | paxillin |
| RABGAP1L | RAB GTPase activating protein 1-like |
| RALGDS | ral guanine nucleotide dissociation stimulator |
| RRAGD | Ras-related GTP binding D |
| RSPH14 | radial spoke head 14 homolog (Chlamydomonas) |
| RSU1 | Ras suppressor protein 1 |
| S100A9 | S100 calcium binding protein A9 |
| SERGEF | secretion regulating guanine nucleotide exchange factor |
| SH3GL3 | SH3-domain GRB2-like 3 |
| SIGLEC15 | sialic acid binding Ig-like lectin 15 |
| SLC16A10 | solute carrier family 16 (aromatic amino acid transporter), member 10 |
| SLC1A7 | solute carrier family 1 (glutamate transporter), member 7 |
| SLC25A21 | solute carrier family 25 (mitochondrial oxoadipate carrier), member 21 |
| SLC35A2 | solute carrier family 35 (UDP-galactose transporter), member A2 |
| SLC7A8 | solute carrier family 7 (amino acid transporter light chain, L system), member 8 |
| SMARCA2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 |
| SSPN | sarcospan |
| STON1 | stonin 1 |
| TBC1D22A | TBC1 domain family, member 22A |
| TCTN2 | tectonic family member 2 |
| THBD | thrombomodulin |
| TIMM50 | translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae) |
| TJAP1 | tight junction associated protein 1 (peripheral) |
| TMEM212 | transmembrane protein 212 |
| TMEM254 | transmembrane protein 254 |
| UTP14A | UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast) |
| WAS | Wiskott-Aldrich syndrome |
| WDR19 | WD repeat domain 19 |
| WDTC1 | WD and tetratricopeptide repeats 1 |
| WHSC1L1 | Wolf-Hirschhorn syndrome candidate 1-like 1 |
| ZCCHC24 | zinc finger, CCHC domain containing 24 |
| ZFHX4 | zinc finger homeobox 4 |
| ZFX | zinc finger protein, X-linked |
| ZNF589 | zinc finger protein 589 |
| ZNF710 | zinc finger protein 710 |
| Symbol | Name |
|---|---|
| ABCC4 | ATP-binding cassette, sub-family C (CFTR/MRP), member 4 |
| ADAP2 | ArfGAP with dual PH domains 2 |
| ANXA2P3 | annexin A2 pseudogene 3 |
| APOC1 | apolipoprotein C-I |
| ASAP1-IT1 | ASAP1 intronic transcript 1 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) |
| ASPHD1 | aspartate beta-hydroxylase domain containing 1 |
| ATAD3A | ATPase family, AAA domain containing 3A |
| AXIN1 | axin 1 |
| BMP4 | bone morphogenetic protein 4 |
| BPGM | 2,3-bisphosphoglycerate mutase |
| C11ORF30 | chromosome 11 open reading frame 30 |
| C9ORF91 | chromosome 9 open reading frame 91 |
| CA11 | carbonic anhydrase XI |
| CBX7 | chromobox homolog 7 |
| CBX8 | chromobox homolog 8 |
| CEP170B | centrosomal protein 170B |
| CEP85 | centrosomal protein 85kDa |
| CHST12 | carbohydrate (chondroitin 4) sulfotransferase 12 |
| CLDN15 | claudin 15 |
| CLN6 | ceroid-lipofuscinosis, neuronal 6, late infantile, variant |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 |
| DCUN1D2 | DCN1, defective in cullin neddylation 1, domain containing 2 |
| DMC1 | DNA meiotic recombinase 1 |
| EPHA2 | EPH receptor A2 |
| ERO1L | ERO1-like (S. cerevisiae) |
| F8 | coagulation factor VIII, procoagulant component |
| FANCE | Fanconi anemia, complementation group E |
| FUT1 | fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group) |
| GAN | gigaxonin |
| GPATCH2L | G patch domain containing 2-like |
| GPC3 | glypican 3 |
| GPRASP1 | G protein-coupled receptor associated sorting protein 1 |
| GSTCD | glutathione S-transferase, C-terminal domain containing |
| GUCY1B2 | guanylate cyclase 1, soluble, beta 2 (pseudogene) |
| HIST1H1D | histone cluster 1, H1d |
| HIST1H3B | histone cluster 1, H3b |
| HIST2H2AA3 | histone cluster 2, H2aa3 |
| HOXC10 | homeobox C10 |
| HSPA2 | heat shock 70kDa protein 2 |
| HTR1E | 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled |
| IL17RA | interleukin 17 receptor A |
| IRAK4 | interleukin-1 receptor-associated kinase 4 |
| KCNF1 | potassium channel, voltage gated modifier subfamily F, member 1 |
| KIF13B | kinesin family member 13B |
| LAMB3 | laminin, beta 3 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 |
| LIG4 | ligase IV, DNA, ATP-dependent |
| LOC730101 | uncharacterized LOC730101 |
| LRFN3 | leucine rich repeat and fibronectin type III domain containing 3 |
| LYPD1 | LY6/PLAUR domain containing 1 |
| MAP9 | microtubule-associated protein 9 |
| MXD3 | MAX dimerization protein 3 |
| NBEAL2 | neurobeachin-like 2 |
| NEK11 | NIMA-related kinase 11 |
| NPFFR1 | neuropeptide FF receptor 1 |
| PARG | poly (ADP-ribose) glycohydrolase |
| PGP | phosphoglycolate phosphatase |
| PILRB | paired immunoglobin-like type 2 receptor beta |
| PLD2 | phospholipase D2 |
| PODXL2 | podocalyxin-like 2 |
| PTPRU | protein tyrosine phosphatase, receptor type, U |
| R3HCC1L | R3H domain and coiled-coil containing 1-like |
| RAB3IL1 | RAB3A interacting protein (rabin3)-like 1 |
| RNASEL | ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent) |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase |
| SH2D4A | SH2 domain containing 4A |
| SLC46A3 | solute carrier family 46, member 3 |
| SPSB1 | splA/ryanodine receptor domain and SOCS box containing 1 |
| TAP1 | transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) |
| TBC1D17 | TBC1 domain family, member 17 |
| TESK1 | testis-specific kinase 1 |
| TICAM1 | toll-like receptor adaptor molecule 1 |
| TMC7 | transmembrane channel-like 7 |
| TMEM120B | transmembrane protein 120B |
| TMEM121 | transmembrane protein 121 |
| TMEM2 | transmembrane protein 2 |
| TMEM57 | transmembrane protein 57 |
| TNRC6B | trinucleotide repeat containing 6B |
| TNS2 | tensin 2 |
| TPCN1 | two pore segment channel 1 |
| TPST2 | tyrosylprotein sulfotransferase 2 |
| TRAIP | TRAF interacting protein |
| TUBGCP5 | tubulin, gamma complex associated protein 5 |
| TUT1 | terminal uridylyl transferase 1, U6 snRNA-specific |
| VAV1 | vav 1 guanine nucleotide exchange factor |
| VPS33A | vacuolar protein sorting 33 homolog A (S. cerevisiae) |
| VWA1 | von Willebrand factor A domain containing 1 |
| XRCC2 | X-ray repair complementing defective repair in Chinese hamster cells 2 |
| XYLT2 | xylosyltransferase II |
| ZNF141 | zinc finger protein 141 |
| ZNF280D | zinc finger protein 280D |
| ZNF701 | zinc finger protein 701 |
| ZNF862 | zinc finger protein 862 |
| ZSCAN31 | zinc finger and SCAN domain containing 31 |