situ Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
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Genes

360 genes co-occuring with the biological term situ in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ABCB5 ATP-binding cassette, sub-family B (MDR/TAP), member 5
ACAD9 acyl-CoA dehydrogenase family, member 9
ADAM10 ADAM metallopeptidase domain 10
ADH4 alcohol dehydrogenase 4 (class II), pi polypeptide
ADM adrenomedullin
AKT1 v-akt murine thymoma viral oncogene homolog 1
ALB albumin
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
ALK anaplastic lymphoma receptor tyrosine kinase
ANKRD1 ankyrin repeat domain 1 (cardiac muscle)
ANKRD30A ankyrin repeat domain 30A
APC adenomatous polyposis coli
APOE apolipoprotein E
APP amyloid beta (A4) precursor protein
AQP2 aquaporin 2 (collecting duct)
AQP3 aquaporin 3 (Gill blood group)
AR androgen receptor
ASCL1 achaete-scute family bHLH transcription factor 1
ATOH1 atonal homolog 1 (Drosophila)
ATP2A3 ATPase, Ca++ transporting, ubiquitous
ATXN3 ataxin 3
BAX BCL2-associated X protein
BID BH3 interacting domain death agonist
BIRC2 baculoviral IAP repeat containing 2
BIRC5 baculoviral IAP repeat containing 5
BRAF B-Raf proto-oncogene, serine/threonine kinase
BRCA1 breast cancer 1, early onset
BRCA2 breast cancer 2, early onset
CA9 carbonic anhydrase IX
CAMK1D calcium/calmodulin-dependent protein kinase ID
CASP14 caspase 14, apoptosis-related cysteine peptidase
CASP3 caspase 3, apoptosis-related cysteine peptidase
CASP8 caspase 8, apoptosis-related cysteine peptidase
CAV1 caveolin 1, caveolae protein, 22kDa
CCL21 chemokine (C-C motif) ligand 21
CCND1 cyclin D1
CCND2 cyclin D2
CCND3 cyclin D3
CD22 CD22 molecule
CD36 CD36 molecule (thrombospondin receptor)
CD40LG CD40 ligand
CD44 CD44 molecule (Indian blood group)
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CDKN2A cyclin-dependent kinase inhibitor 2A
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CEBPB CCAAT/enhancer binding protein (C/EBP), beta
CFH complement factor H
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
CHEK1 checkpoint kinase 1
CHIC2 cysteine-rich hydrophobic domain 2
CHRNA4 cholinergic receptor, nicotinic, alpha 4 (neuronal)
CLDN4 claudin 4
CLDN7 claudin 7
COCH cochlin
COL18A1 collagen, type XVIII, alpha 1
CREB1 cAMP responsive element binding protein 1
CREBBP CREB binding protein
CRISP3 cysteine-rich secretory protein 3
CRP C-reactive protein, pentraxin-related
CRTC1 CREB regulated transcription coactivator 1
CRYGD crystallin, gamma D
CSF1R colony stimulating factor 1 receptor
CSK c-src tyrosine kinase
CST6 cystatin E/M
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CTNND1 catenin (cadherin-associated protein), delta 1
CTSD cathepsin D
CUTA cutA divalent cation tolerance homolog (E. coli)
CXCL10 chemokine (C-X-C motif) ligand 10
CXCR4 chemokine (C-X-C motif) receptor 4
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1
DCN decorin
DDIT3 DNA-damage-inducible transcript 3
DEFA1 defensin, alpha 1
DEFB103B defensin, beta 103B
DEFB106A defensin, beta 106A
DIABLO diablo, IAP-binding mitochondrial protein
DIRAS3 DIRAS family, GTP-binding RAS-like 3
DLD dihydrolipoamide dehydrogenase
DLGAP2 discs, large (Drosophila) homolog-associated protein 2
DLST dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex)
DMRT1 doublesex and mab-3 related transcription factor 1
DUX4L1 double homeobox 4 like 1
EDN1 endothelin 1
EGF epidermal growth factor
EGFR epidermal growth factor receptor
EGR1 early growth response 1
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3
ELN elastin
ENTPD3 ectonucleoside triphosphate diphosphohydrolase 3
EPCAM epithelial cell adhesion molecule
ERBB2 erb-b2 receptor tyrosine kinase 2
ERBB3 erb-b2 receptor tyrosine kinase 3
ERBB4 erb-b2 receptor tyrosine kinase 4
ERG v-ets avian erythroblastosis virus E26 oncogene homolog
ESCO2 establishment of sister chromatid cohesion N-acetyltransferase 2
ESR1 estrogen receptor 1
ESR2 estrogen receptor 2 (ER beta)
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2
ETV6 ets variant 6
EWSR1 EWS RNA-binding protein 1
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit
F10 coagulation factor X
F2 coagulation factor II (thrombin)
FAP fibroblast activation protein, alpha
FGF10 fibroblast growth factor 10
FGF18 fibroblast growth factor 18
FGF23 fibroblast growth factor 23
FGFR4 fibroblast growth factor receptor 4
FHIT fragile histidine triad
FIP1L1 factor interacting with PAPOLA and CPSF1
FOXC1 forkhead box C1
FRA2H fragile site, aphidicolin type, common, fra(2)(q32.1)
FSHMD1A facioscapulohumeral muscular dystrophy 1A
FSHR follicle stimulating hormone receptor
GATA3 GATA binding protein 3
GDF15 growth differentiation factor 15
GH1 growth hormone 1
GHRL ghrelin/obestatin prepropeptide
GJA1 gap junction protein, alpha 1, 43kDa
GLS2 glutaminase 2 (liver, mitochondrial)
GLTSCR2 glioma tumor suppressor candidate region gene 2
GMNN geminin, DNA replication inhibitor
GNB2L1 guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1
GPR182 G protein-coupled receptor 182
GRIN1 glutamate receptor, ionotropic, N-methyl D-aspartate 1
GRIN2B glutamate receptor, ionotropic, N-methyl D-aspartate 2B
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
H2AFX H2A histone family, member X
HAMP hepcidin antimicrobial peptide
HCN1 hyperpolarization activated cyclic nucleotide gated potassium channel 1
HCN2 hyperpolarization activated cyclic nucleotide gated potassium channel 2
HDAC11 histone deacetylase 11
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HMGA1 high mobility group AT-hook 1
HMGA2 high mobility group AT-hook 2
HMGB1 high mobility group box 1
HMMR hyaluronan-mediated motility receptor (RHAMM)
HMOX1 heme oxygenase 1
HNF1A HNF1 homeobox A
ICAM1 intercellular adhesion molecule 1
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble
IFNG interferon, gamma
IGF1R insulin-like growth factor 1 receptor
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3
IGL immunoglobulin lambda locus
IL12B interleukin 12B
IL17A interleukin 17A
IL1B interleukin 1, beta
IL2 interleukin 2
IL23A interleukin 23, alpha subunit p19
IL3 interleukin 3
IL4 interleukin 4
INHBA inhibin, beta A
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
JAZF1 JAZF zinc finger 1
JUN jun proto-oncogene
KAZALD1 Kazal-type serine peptidase inhibitor domain 1
KCNS3 potassium voltage-gated channel, modifier subfamily S, member 3
KIAA0100 KIAA0100
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KLF4 Kruppel-like factor 4 (gut)
KLF5 Kruppel-like factor 5 (intestinal)
KLK7 kallikrein-related peptidase 7
KLRK1 killer cell lectin-like receptor subfamily K, member 1
KMT2A lysine (K)-specific methyltransferase 2A
KRAS Kirsten rat sarcoma viral oncogene homolog
KRT13 keratin 13, type I
KRT15 keratin 15, type I
KRTAP24-1 keratin associated protein 24-1
LGALS1 lectin, galactoside-binding, soluble, 1
LGALS7 lectin, galactoside-binding, soluble, 7
LGALS9 lectin, galactoside-binding, soluble, 9
LPA lipoprotein, Lp(a)
MAML2 mastermind-like 2 (Drosophila)
MAP1LC3A microtubule-associated protein 1 light chain 3 alpha
MAP3K11 mitogen-activated protein kinase kinase kinase 11
MAPK1 mitogen-activated protein kinase 1
MAPK3 mitogen-activated protein kinase 3
MARCO macrophage receptor with collagenous structure
MARVELD2 MARVEL domain containing 2
MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
MC4R melanocortin 4 receptor
MCM2 minichromosome maintenance complex component 2
MDK midkine (neurite growth-promoting factor 2)
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MEIS2 Meis homeobox 2
MEN1 multiple endocrine neoplasia I
MET MET proto-oncogene, receptor tyrosine kinase
MIB1 mindbomb E3 ubiquitin protein ligase 1
MIR155 microRNA 155
MIR30A microRNA 30a
MITF microphthalmia-associated transcription factor
MKI67 marker of proliferation Ki-67
MLANA melan-A
MME membrane metallo-endopeptidase
MMP1 matrix metallopeptidase 1
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MMP2 matrix metallopeptidase 2
MMP9 matrix metallopeptidase 9
MSH6 mutS homolog 6
MSLN mesothelin
MT-ND4 NADH dehydrogenase, subunit 4 (complex I)
MTAP methylthioadenosine phosphorylase
MUC1 mucin 1, cell surface associated
MYBPC3 myosin binding protein C, cardiac
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYCN v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog
NANOG Nanog homeobox
NAV3 neuron navigator 3
NCOA3 nuclear receptor coactivator 3
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NEDD8 neural precursor cell expressed, developmentally down-regulated 8
NEK2 NIMA-related kinase 2
NES nestin
NF1 neurofibromin 1
NF2 neurofibromin 2 (merlin)
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NKX2-1 NK2 homeobox 1
NME1 NME/NM23 nucleoside diphosphate kinase 1
NOS2 nitric oxide synthase 2, inducible
NR0B1 nuclear receptor subfamily 0, group B, member 1
NR1D1 nuclear receptor subfamily 1, group D, member 1
NRP1 neuropilin 1
NTRK1 neurotrophic tyrosine kinase, receptor, type 1
OGDH oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
OGG1 8-oxoguanine DNA glycosylase
PAX2 paired box 2
PAX6 paired box 6
PAX8 paired box 8
PCBD1 pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha
PCNA proliferating cell nuclear antigen
PDGFB platelet-derived growth factor beta polypeptide
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PDGFRB platelet-derived growth factor receptor, beta polypeptide
PDIA6 protein disulfide isomerase family A, member 6
PDS5B PDS5 cohesin associated factor B
PECAM1 platelet/endothelial cell adhesion molecule 1
PELP1 proline, glutamate and leucine rich protein 1
PGR progesterone receptor
PHF1 PHD finger protein 1
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PKD1 polycystic kidney disease 1 (autosomal dominant)
PLAG1 pleiomorphic adenoma gene 1
PLAUR plasminogen activator, urokinase receptor
PLD1 phospholipase D1, phosphatidylcholine-specific
PLIN1 perilipin 1
PLK1 polo-like kinase 1
PML promyelocytic leukemia
POMC proopiomelanocortin
POT1 protection of telomeres 1
POU5F1 POU class 5 homeobox 1
PPP2R2B protein phosphatase 2, regulatory subunit B, beta
PRDM16 PR domain containing 16
PRF1 perforin 1 (pore forming protein)
PROM2 prominin 2
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10
PSMD6 proteasome (prosome, macropain) 26S subunit, non-ATPase, 6
PTEN phosphatase and tensin homolog
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTPN1 protein tyrosine phosphatase, non-receptor type 1
PYCARD PYD and CARD domain containing
RAF1 Raf-1 proto-oncogene, serine/threonine kinase
RARA retinoic acid receptor, alpha
RARB retinoic acid receptor, beta
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
RBM39 RNA binding motif protein 39
REG1A regenerating islet-derived 1 alpha
RET ret proto-oncogene
RMDN3 regulator of microtubule dynamics 3
RNU2-1 RNA, U2 small nuclear 1
RNU6-1 RNA, U6 small nuclear 1
ROS1 ROS proto-oncogene 1 , receptor tyrosine kinase
RPL22 ribosomal protein L22
RUNX3 runt-related transcription factor 3
RYR3 ryanodine receptor 3
S100A4 S100 calcium binding protein A4
S100A7 S100 calcium binding protein A7
S100A8 S100 calcium binding protein A8
S100A9 S100 calcium binding protein A9
SCGB3A1 secretoglobin, family 3A, member 1
SCGB3A2 secretoglobin, family 3A, member 2
SCHIP1 schwannomin interacting protein 1
SCNN1D sodium channel, non voltage gated 1 delta subunit
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5
SET SET nuclear proto-oncogene
SIRT7 sirtuin 7
SLC16A4 solute carrier family 16, member 4
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1
SLC35C2 solute carrier family 35 (GDP-fucose transporter), member C2
SLC39A6 solute carrier family 39 (zinc transporter), member 6
SLC43A2 solute carrier family 43 (amino acid system L transporter), member 2
SMC1A structural maintenance of chromosomes 1A
SOD1 superoxide dismutase 1, soluble
SOX10 SRY (sex determining region Y)-box 10
SP1 Sp1 transcription factor
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
SPECC1 sperm antigen with calponin homology and coiled-coil domains 1
SPON1 spondin 1, extracellular matrix protein
SPTAN1 spectrin, alpha, non-erythrocytic 1
SREBF1 sterol regulatory element binding transcription factor 1
ST5 suppression of tumorigenicity 5
STAR steroidogenic acute regulatory protein
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STAT5A signal transducer and activator of transcription 5A
STS steroid sulfatase (microsomal), isozyme S
SULT1E1 sulfotransferase family 1E, estrogen-preferring, member 1
TBX1 T-box 1
TBX3 T-box 3
TBX5 T-box 5
TERF2 telomeric repeat binding factor 2
TERT telomerase reverse transcriptase
TF transferrin
TG thyroglobulin
TGFB1 transforming growth factor, beta 1
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
TGM2 transglutaminase 2
TH tyrosine hydroxylase
TIMP1 TIMP metallopeptidase inhibitor 1
TIMP2 TIMP metallopeptidase inhibitor 2
TJP1 tight junction protein 1
TJP2 tight junction protein 2
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
TMPRSS2 transmembrane protease, serine 2
TNF tumor necrosis factor
TNFRSF6B tumor necrosis factor receptor superfamily, member 6b, decoy
TNNC1 troponin C type 1 (slow)
TOP2A topoisomerase (DNA) II alpha 170kDa
TP53 tumor protein p53
TP53BP1 tumor protein p53 binding protein 1
TP53INP1 tumor protein p53 inducible nuclear protein 1
TP63 tumor protein p63
TP73 tumor protein p73
TPD52 tumor protein D52
TRD T cell receptor delta locus
TRG T cell receptor gamma locus
TRH thyrotropin-releasing hormone
TRPM8 transient receptor potential cation channel, subfamily M, member 8
TRPS1 trichorhinophalangeal syndrome I
TRPV6 transient receptor potential cation channel, subfamily V, member 6
TSC2 tuberous sclerosis 2
TSHR thyroid stimulating hormone receptor
TSPY1 testis specific protein, Y-linked 1
TYR tyrosinase
VCAN versican
VEGFA vascular endothelial growth factor A
VIM vimentin
WDR77 WD repeat domain 77
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta