skimmianine-2504 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the skimmianine-2504 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ACO2 aconitase 2, mitochondrial
ATP1A3 ATPase, Na+/K+ transporting, alpha 3 polypeptide
BAIAP3 BAI1-associated protein 3
BIN1 bridging integrator 1
BLK BLK proto-oncogene, Src family tyrosine kinase
BTRC beta-transducin repeat containing E3 ubiquitin protein ligase
C8A complement component 8, alpha polypeptide
CACNG1 calcium channel, voltage-dependent, gamma subunit 1
CALCR calcitonin receptor
CALD1 caldesmon 1
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1
CD59 CD59 molecule, complement regulatory protein
CD68 CD68 molecule
CD8B CD8b molecule
CDH6 cadherin 6, type 2, K-cadherin (fetal kidney)
CDK5R2 cyclin-dependent kinase 5, regulatory subunit 2 (p39)
CDX1 caudal type homeobox 1
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
CLEC3B C-type lectin domain family 3, member B
CYFIP2 cytoplasmic FMR1 interacting protein 2
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6
DGKQ diacylglycerol kinase, theta 110kDa
DLGAP1 discs, large (Drosophila) homolog-associated protein 1
DNAH3 dynein, axonemal, heavy chain 3
DPT dermatopontin
ENPEP glutamyl aminopeptidase (aminopeptidase A)
EPS15L1 epidermal growth factor receptor pathway substrate 15-like 1
FBP1 fructose-1,6-bisphosphatase 1
FLJ11292
FUBP1 far upstream element (FUSE) binding protein 1
GAD1 glutamate decarboxylase 1 (brain, 67kDa)
GAD2 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
GALR2 galanin receptor 2
GPR1 G protein-coupled receptor 1
GULP1 GULP, engulfment adaptor PTB domain containing 1
HIST1H2AJ histone cluster 1, H2aj
HIST1H2BJ histone cluster 1, H2bj
HOXA4 homeobox A4
HOXC4 homeobox C4
IGHM immunoglobulin heavy constant mu
IKZF4 IKAROS family zinc finger 4 (Eos)
IL1RAPL2 interleukin 1 receptor accessory protein-like 2
KCNJ3 potassium channel, inwardly rectifying subfamily J, member 3
KCNK10 potassium channel, two pore domain subfamily K, member 10
KIAA0391 KIAA0391
KLHL23 kelch-like family member 23
KRT85 keratin 85, type II
LBX1 ladybird homeobox 1
LIMS2 LIM and senescent cell antigen-like domains 2
MARCKS myristoylated alanine-rich protein kinase C substrate
MGC2889 uncharacterized protein MGC2889
MISP mitotic spindle positioning
NLRP1 NLR family, pyrin domain containing 1
NPR1 natriuretic peptide receptor 1
NR2F1 nuclear receptor subfamily 2, group F, member 1
OR1G1 olfactory receptor, family 1, subfamily G, member 1
PDLIM4 PDZ and LIM domain 4
PHLDA1 pleckstrin homology-like domain, family A, member 1
PKIA protein kinase (cAMP-dependent, catalytic) inhibitor alpha
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific)
PLSCR3 phospholipid scramblase 3
POU6F2 POU class 6 homeobox 2
PRB1 proline-rich protein BstNI subfamily 1
PRELP proline/arginine-rich end leucine-rich repeat protein
RAP1GAP RAP1 GTPase activating protein
RB1 retinoblastoma 1
RGS6 regulator of G-protein signaling 6
RIMS2 regulating synaptic membrane exocytosis 2
ROCK2 Rho-associated, coiled-coil containing protein kinase 2
RPL23AP32 ribosomal protein L23a pseudogene 32
RUNX1 runt-related transcription factor 1
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SERPINB13 serpin peptidase inhibitor, clade B (ovalbumin), member 13
SIGLEC1 sialic acid binding Ig-like lectin 1, sialoadhesin
SLC22A18AS solute carrier family 22 (organic cation transporter), member 18 antisense
SLC28A3 solute carrier family 28 (concentrative nucleoside transporter), member 3
SLC34A1 solute carrier family 34 (type II sodium/phosphate cotransporter), member 1
SLC6A1 solute carrier family 6 (neurotransmitter transporter), member 1
SLCO1A2 solute carrier organic anion transporter family, member 1A2
SLN sarcolipin
SOX2 SRY (sex determining region Y)-box 2
SPINK5 serine peptidase inhibitor, Kazal type 5
SSTR5 somatostatin receptor 5
STS steroid sulfatase (microsomal), isozyme S
TAGLN3 transgelin 3
TBX1 T-box 1
TCP11L1 t-complex 11, testis-specific-like 1
TEF thyrotrophic embryonic factor
TFAP2B transcription factor AP-2 beta (activating enhancer binding protein 2 beta)
THPO thrombopoietin
TMPRSS15 transmembrane protease, serine 15
TRD T cell receptor delta locus
TRIM31 tripartite motif containing 31
TTC38 tetratricopeptide repeat domain 38
USP27X ubiquitin specific peptidase 27, X-linked
VCL vinculin
ZBTB16 zinc finger and BTB domain containing 16
ZCCHC4 zinc finger, CCHC domain containing 4
ZNF639 zinc finger protein 639

decreased expression

Symbol Name
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1
APOBR apolipoprotein B receptor
ARHGEF1 Rho guanine nucleotide exchange factor (GEF) 1
BCORL1 BCL6 corepressor-like 1
BRIP1 BRCA1 interacting protein C-terminal helicase 1
C21ORF91 chromosome 21 open reading frame 91
C8ORF44 chromosome 8 open reading frame 44
CCDC176 coiled-coil domain containing 176
CD101 CD101 molecule
CFAP44 cilia and flagella associated protein 44
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CLN6 ceroid-lipofuscinosis, neuronal 6, late infantile, variant
COL4A2 collagen, type IV, alpha 2
DEF8 differentially expressed in FDCP 8 homolog (mouse)
DENND4A DENN/MADD domain containing 4A
DGAT1 diacylglycerol O-acyltransferase 1
DIP2A DIP2 disco-interacting protein 2 homolog A (Drosophila)
DOLPP1 dolichyldiphosphatase 1
ERAP2 endoplasmic reticulum aminopeptidase 2
FAM188A family with sequence similarity 188, member A
FAM216A family with sequence similarity 216, member A
GNL2 guanine nucleotide binding protein-like 2 (nucleolar)
GSTCD glutathione S-transferase, C-terminal domain containing
GUSBP3 glucuronidase, beta pseudogene 3
HAUS6 HAUS augmin-like complex, subunit 6
HIRA histone cell cycle regulator
IMPAD1 inositol monophosphatase domain containing 1
INPP5E inositol polyphosphate-5-phosphatase, 72 kDa
IRAK4 interleukin-1 receptor-associated kinase 4
JMJD4 jumonji domain containing 4
KATNBL1 katanin p80 subunit B-like 1
KCNA3 potassium channel, voltage gated shaker related subfamily A, member 3
KIAA0922 KIAA0922
KIF1B kinesin family member 1B
KIF23 kinesin family member 23
KPNA4 karyopherin alpha 4 (importin alpha 3)
LILRB4 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 4
LIN7A lin-7 homolog A (C. elegans)
LINC00339 long intergenic non-protein coding RNA 339
LMAN1 lectin, mannose-binding, 1
LRIG2 leucine-rich repeats and immunoglobulin-like domains 2
LTBR lymphotoxin beta receptor (TNFR superfamily, member 3)
LZTR1 leucine-zipper-like transcription regulator 1
MOCOS molybdenum cofactor sulfurase
MTFR1 mitochondrial fission regulator 1
NABP2 nucleic acid binding protein 2
NAGPA N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase
NIP7 NIP7, nucleolar pre-rRNA processing protein
NMRK1 nicotinamide riboside kinase 1
NTSR1 neurotensin receptor 1 (high affinity)
PCYOX1 prenylcysteine oxidase 1
PDP1 pyruvate dehyrogenase phosphatase catalytic subunit 1
PDZD7 PDZ domain containing 7
PGM3 phosphoglucomutase 3
PIGK phosphatidylinositol glycan anchor biosynthesis, class K
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PLA2G12A phospholipase A2, group XIIA
PLA2G15 phospholipase A2, group XV
PRMT7 protein arginine methyltransferase 7
PTCD2 pentatricopeptide repeat domain 2
RABAC1 Rab acceptor 1 (prenylated)
RARS arginyl-tRNA synthetase
RECQL4 RecQ protein-like 4
RHOBTB1 Rho-related BTB domain containing 1
RNF31 ring finger protein 31
RPL13P5 ribosomal protein L13 pseudogene 5
RPL23AP7 ribosomal protein L23a pseudogene 7
RSAD1 radical S-adenosyl methionine domain containing 1
RUSC2 RUN and SH3 domain containing 2
RUVBL1 RuvB-like AAA ATPase 1
SERTAD3 SERTA domain containing 3
SFXN1 sideroflexin 1
SIGIRR single immunoglobulin and toll-interleukin 1 receptor (TIR) domain
SLC12A9 solute carrier family 12, member 9
SLC15A3 solute carrier family 15 (oligopeptide transporter), member 3
SLC9A8 solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
SNRPN small nuclear ribonucleoprotein polypeptide N
SPATA7 spermatogenesis associated 7
SPR sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase)
STIM1 stromal interaction molecule 1
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TRAIP TRAF interacting protein
TSSC4 tumor suppressing subtransferable candidate 4
TTC26 tetratricopeptide repeat domain 26
ULK1 unc-51 like autophagy activating kinase 1
UNC93B1 unc-93 homolog B1 (C. elegans)
VCPKMT valosin containing protein lysine (K) methyltransferase
VILL villin-like
VPS54 vacuolar protein sorting 54 homolog (S. cerevisiae)
ZC3H3 zinc finger CCCH-type containing 3
ZHX2 zinc fingers and homeoboxes 2
ZNF141 zinc finger protein 141
ZNF227 zinc finger protein 227
ZNF32 zinc finger protein 32
ZNF551 zinc finger protein 551
ZNF573 zinc finger protein 573
ZNF721 zinc finger protein 721
ZNF8 zinc finger protein 8