skimmianine-6066 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

192 genes differentially expressed following the skimmianine-6066 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADAM22 ADAM metallopeptidase domain 22
ADRA1D adrenoceptor alpha 1D
AHSP alpha hemoglobin stabilizing protein
AIM1L absent in melanoma 1-like
AKAP8L A kinase (PRKA) anchor protein 8-like
B3GNTL1 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like 1
BEGAIN brain-enriched guanylate kinase-associated
BEX1 brain expressed, X-linked 1
BMP1 bone morphogenetic protein 1
C1ORF95 chromosome 1 open reading frame 95
CACNA1I calcium channel, voltage-dependent, T type, alpha 1I subunit
CALD1 caldesmon 1
CCL22 chemokine (C-C motif) ligand 22
CD163 CD163 molecule
CD1A CD1a molecule
CD300C CD300c molecule
CD48 CD48 molecule
CD8B CD8b molecule
CEBPD CCAAT/enhancer binding protein (C/EBP), delta
CLCN6 chloride channel, voltage-sensitive 6
CLEC7A C-type lectin domain family 7, member A
COL6A1 collagen, type VI, alpha 1
CPA3 carboxypeptidase A3 (mast cell)
CYLD cylindromatosis (turban tumor syndrome)
DIO2 deiodinase, iodothyronine, type II
DNAJB5 DnaJ (Hsp40) homolog, subfamily B, member 5
DOCK10 dedicator of cytokinesis 10
DPT dermatopontin
EML2 echinoderm microtubule associated protein like 2
EN1 engrailed homeobox 1
EPM2A epilepsy, progressive myoclonus type 2A, Lafora disease (laforin)
FCN2 ficolin (collagen/fibrinogen domain containing lectin) 2
FEZ1 fasciculation and elongation protein zeta 1 (zygin I)
FLT3LG fms-related tyrosine kinase 3 ligand
GIPR gastric inhibitory polypeptide receptor
GNAO1 guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
GNG7 guanine nucleotide binding protein (G protein), gamma 7
GP1BB glycoprotein Ib (platelet), beta polypeptide
GREB1L growth regulation by estrogen in breast cancer-like
GULP1 GULP, engulfment adaptor PTB domain containing 1
HNF4A hepatocyte nuclear factor 4, alpha
HOPX HOP homeobox
HPX hemopexin
HR hair growth associated
ICA1 islet cell autoantigen 1, 69kDa
ICOSLG inducible T-cell co-stimulator ligand
IFI6 interferon, alpha-inducible protein 6
IGLL3P immunoglobulin lambda-like polypeptide 3, pseudogene
INPP5D inositol polyphosphate-5-phosphatase, 145kDa
IPW imprinted in Prader-Willi syndrome (non-protein coding)
ITGA2B integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
KCNK10 potassium channel, two pore domain subfamily K, member 10
KIAA0040 KIAA0040
KLK7 kallikrein-related peptidase 7
LIF leukemia inhibitory factor
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAP4K2 mitogen-activated protein kinase kinase kinase kinase 2
MBD2 methyl-CpG binding domain protein 2
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
MST1 macrophage stimulating 1
MTCP1 mature T-cell proliferation 1
MTSS1 metastasis suppressor 1
OMD osteomodulin
OSBPL3 oxysterol binding protein-like 3
PHEX phosphate regulating endopeptidase homolog, X-linked
PHLDB1 pleckstrin homology-like domain, family B, member 1
PMFBP1 polyamine modulated factor 1 binding protein 1
PML promyelocytic leukemia
PRB1 proline-rich protein BstNI subfamily 1
PRDM1 PR domain containing 1, with ZNF domain
PSD3 pleckstrin and Sec7 domain containing 3
PTHLH parathyroid hormone-like hormone
PTPN1 protein tyrosine phosphatase, non-receptor type 1
RECQL5 RecQ protein-like 5
RUNDC3A RUN domain containing 3A
S100A8 S100 calcium binding protein A8
SCNN1G sodium channel, non voltage gated 1 gamma subunit
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1
SMC4 structural maintenance of chromosomes 4
SNTA1 syntrophin, alpha 1
SOX21 SRY (sex determining region Y)-box 21
SPTAN1 spectrin, alpha, non-erythrocytic 1
SULT4A1 sulfotransferase family 4A, member 1
TAC3 tachykinin 3
TBC1D19 TBC1 domain family, member 19
TLR8 toll-like receptor 8
TMEM63A transmembrane protein 63A
TMX4 thioredoxin-related transmembrane protein 4
TRIL TLR4 interactor with leucine-rich repeats
TRMT1 tRNA methyltransferase 1 homolog (S. cerevisiae)
TRO trophinin
TTC38 tetratricopeptide repeat domain 38
VIPR1 vasoactive intestinal peptide receptor 1
ZFP64 ZFP64 zinc finger protein
ZNF154 zinc finger protein 154
ZNF507 zinc finger protein 507

decreased expression

Symbol Name
AMT aminomethyltransferase
AP1S1 adaptor-related protein complex 1, sigma 1 subunit
AUTS2 autism susceptibility candidate 2
C3ORF18 chromosome 3 open reading frame 18
C5AR2 complement component 5a receptor 2
CCDC132 coiled-coil domain containing 132
CD83 CD83 molecule
CDADC1 cytidine and dCMP deaminase domain containing 1
CDC42EP1 CDC42 effector protein (Rho GTPase binding) 1
CEMIP cell migration inducing protein, hyaluronan binding
CFD complement factor D (adipsin)
CHKB choline kinase beta
CHST8 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8
CIC capicua transcriptional repressor
CLSPN claspin
CNGB3 cyclic nucleotide gated channel beta 3
CNTN1 contactin 1
CRIP1 cysteine-rich protein 1 (intestinal)
CXORF56 chromosome X open reading frame 56
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
DUSP2 dual specificity phosphatase 2
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
EFNA3 ephrin-A3
FAM114A2 family with sequence similarity 114, member A2
FAM131A family with sequence similarity 131, member A
GADD45G growth arrest and DNA-damage-inducible, gamma
GMPR guanosine monophosphate reductase
GPRIN2 G protein regulated inducer of neurite outgrowth 2
GTF2A1 general transcription factor IIA, 1, 19/37kDa
GUSBP3 glucuronidase, beta pseudogene 3
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5
HIRA histone cell cycle regulator
HIST1H2BC histone cluster 1, H2bc
HOXB2 homeobox B2
HS3ST3A1 heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1
HSPA1L heat shock 70kDa protein 1-like
HYI hydroxypyruvate isomerase (putative)
IFNA14 interferon, alpha 14
IQCG IQ motif containing G
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
JUNB jun B proto-oncogene
KIAA0125 KIAA0125
KIAA0319L KIAA0319-like
KPNA5 karyopherin alpha 5 (importin alpha 6)
KRT24 keratin 24, type I
LOXL3 lysyl oxidase-like 3
MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
MCOLN1 mucolipin 1
N4BP3 NEDD4 binding protein 3
NCALD neurocalcin delta
NOD1 nucleotide-binding oligomerization domain containing 1
NPFFR1 neuropeptide FF receptor 1
ONECUT2 one cut homeobox 2
PCDHB8 protocadherin beta 8
PDK4 pyruvate dehydrogenase kinase, isozyme 4
PHLPP1 PH domain and leucine rich repeat protein phosphatase 1
PICK1 protein interacting with PRKCA 1
PIGN phosphatidylinositol glycan anchor biosynthesis, class N
PIGQ phosphatidylinositol glycan anchor biosynthesis, class Q
PIM1 Pim-1 proto-oncogene, serine/threonine kinase
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PLEKHA6 pleckstrin homology domain containing, family A member 6
POLL polymerase (DNA directed), lambda
PTPRCAP protein tyrosine phosphatase, receptor type, C-associated protein
RAB40C RAB40C, member RAS oncogene family
RFXAP regulatory factor X-associated protein
RIN2 Ras and Rab interactor 2
RNF126P1 ring finger protein 126 pseudogene 1
RPL23AP32 ribosomal protein L23a pseudogene 32
RUSC2 RUN and SH3 domain containing 2
SH2D4A SH2 domain containing 4A
SLC17A2 solute carrier family 17, member 2
SLC20A2 solute carrier family 20 (phosphate transporter), member 2
SRPX sushi-repeat containing protein, X-linked
SSBP3 single stranded DNA binding protein 3
ST5 suppression of tumorigenicity 5
STEAP1 six transmembrane epithelial antigen of the prostate 1
STK16 serine/threonine kinase 16
SYCP2 synaptonemal complex protein 2
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1
TAOK1 TAO kinase 1
TEP1 telomerase-associated protein 1
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
TFF2 trefoil factor 2
TGFB1I1 transforming growth factor beta 1 induced transcript 1
THRAP3 thyroid hormone receptor associated protein 3
TICAM1 toll-like receptor adaptor molecule 1
TOLLIP toll interacting protein
TSC22D4 TSC22 domain family, member 4
VEGFC vascular endothelial growth factor C
WDR76 WD repeat domain 76
WNT10B wingless-type MMTV integration site family, member 10B
ZDHHC11 zinc finger, DHHC-type containing 11
ZNF350 zinc finger protein 350
ZNF74 zinc finger protein 74