skin development Gene Set

Dataset GO Biological Process Annotations 2025
Category structural or functional annotations
Type biological process
Description The process whose specific outcome is the progression of the skin over time, from its formation to the mature structure. The skin is the external membranous integument of an animal. In vertebrates the skin generally consists of two layers, an outer nonsensitive and nonvascular epidermis (cuticle or skarfskin) composed of cells which are constantly growing and multiplying in the deeper, and being thrown off in the superficial layers, as well as an inner vascular dermis (cutis, corium or true skin) composed mostly of connective tissue. (Gene Ontology, GO_0043588)
External Link http://amigo.geneontology.org/amigo/term/GO:0043588
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Genes

70 genes participating in the skin development biological process from the curated GO Biological Process Annotations 2025 dataset.

Symbol Name
ABCA12 ATP-binding cassette, sub-family A (ABC1), member 12
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group)
ACER1 alkaline ceramidase 1
ADAM9 ADAM metallopeptidase domain 9
AHDC1 AT hook, DNA binding motif, containing 1
AKR1C3 aldo-keto reductase family 1, member C3
ANXA1 annexin A1
ASAH1 N-acylsphingosine amidohydrolase (acid ceramidase) 1
ASCL4 achaete-scute family bHLH transcription factor 4
ASPRV1 aspartic peptidase, retroviral-like 1
ATP7A ATPase, Cu++ transporting, alpha polypeptide
BCR breakpoint cluster region
CASP3 caspase 3, apoptosis-related cysteine peptidase
CDSN corneodesmosin
CERS3 ceramide synthase 3
CLIC4 chloride intracellular channel 4
COL1A1 collagen, type I, alpha 1
COL1A2 collagen, type I, alpha 2
COL3A1 collagen, type III, alpha 1
COL5A1 collagen, type V, alpha 1
COL5A2 collagen, type V, alpha 2
COL5A3 collagen, type V, alpha 3
CSTA cystatin A (stefin A)
DACT2 dishevelled-binding antagonist of beta-catenin 2
DHCR24 24-dehydrocholesterol reductase
DLL1 delta-like 1 (Drosophila)
DSPP dentin sialophosphoprotein
EPHA2 EPH receptor A2
EREG epiregulin
ERRFI1 ERBB receptor feedback inhibitor 1
EVPL envoplakin
FLG filaggrin
GATA6 GATA binding protein 6
GRHL2 grainyhead-like 2 (Drosophila)
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
ITGA6 integrin, alpha 6
ITGB4 integrin, beta 4
IVL involucrin
JAG1 jagged 1
KRT10 keratin 10, type I
KRT16 keratin 16, type I
KRT9 keratin 9, type I
LORICRIN loricrin cornified envelope precursor protein
MBD4 methyl-CpG binding domain protein 4
OPN3 opsin 3
PDGFA platelet-derived growth factor alpha polypeptide
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PKD1 polycystic kidney disease 1 (autosomal dominant)
POU2F3 POU class 2 homeobox 3
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme
RIPK4 receptor-interacting serine-threonine kinase 4
RYR1 ryanodine receptor 1 (skeletal)
S100A7 S100 calcium binding protein A7
SCEL sciellin
SLC2A10 solute carrier family 2 (facilitated glucose transporter), member 10
SPRR1A small proline-rich protein 1A
SPRR1B small proline-rich protein 1B
SPRR2B small proline-rich protein 2B
SPRR2F small proline-rich protein 2F
SPRR2G small proline-rich protein 2G
SPRR3 small proline-rich protein 3
ST14 suppression of tumorigenicity 14 (colon carcinoma)
TGM1 transglutaminase 1
TGM3 transglutaminase 3
TXNIP thioredoxin interacting protein
UGCG UDP-glucose ceramide glucosyltransferase
VPS33B vacuolar protein sorting 33 homolog B (yeast)
WNT10A wingless-type MMTV integration site family, member 10A
WNT16 wingless-type MMTV integration site family, member 16
WNT5A wingless-type MMTV integration site family, member 5A