| Dataset | GeneRIF Biological Term Annotations |
| Category | structural or functional annotations |
| Type | biological term |
| Description | solute carrier family 1 (glial high affinity glutamate transporter), member 2|This gene encodes a member of a family of solute transporter proteins. The membrane-bound protein is the principal transporter that clears the excitatory neurotransmitter glutamate from the extracellular space at synapses in the central nervous system. Glutamate clearance is necessary for proper synaptic activation and to prevent neuronal damage from excessive activation of glutamate receptors. Mutations in and decreased expression of this protein are associated with amyotrophic lateral sclerosis. Alternatively spliced transcript variants of this gene have been identified. [provided by RefSeq, Sep 2010] (NCBI Entrez Gene Database, 6506) |
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3 genes co-occuring with the biological term slc1a2 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.
