slx1-slx4 complex Gene Set

Dataset COMPARTMENTS Text-mining Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description A heterodimeric protein complex that possesses an endonuclease activity that specifically cleaves certain types of branched DNA structures; because such structures often form during the replication ribosomal DNA (rDNA) repeats, the complex plays a role in the maintenance of rDNA. The subunits are known as Slx1 and Slx 4 in budding and fission yeasts, and are conserved in eukaryotes. (Gene Ontology, GO_0033557)
Similar Terms
Downloads & Tools

Genes

23 proteins co-occuring with the slx1-slx4 complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
GEN1 GEN1 Holliday junction 5' flap endonuclease 2.2194
SLX4 SLX4 structure-specific endonuclease subunit 2.05249
MUS81 MUS81 structure-specific endonuclease subunit 2.01628
RMI2 RecQ mediated genome instability 2 1.69399
RMI1 RecQ mediated genome instability 1 1.5972
GPR148 G protein-coupled receptor 148 1.53839
SLX4IP SLX4 interacting protein 1.50622
EME1 essential meiotic structure-specific endonuclease 1 1.32005
TERF2IP telomeric repeat binding factor 2, interacting protein 1.15057
ERCC4 excision repair cross-complementation group 4 1.09951
MLH3 mutL homolog 3 0.838728
ERCC1 excision repair cross-complementation group 1 0.784156
TERF2 telomeric repeat binding factor 2 0.648291
BLM Bloom syndrome, RecQ helicase-like 0.616285
ATR ATR serine/threonine kinase 0.608241
ERCC5 excision repair cross-complementation group 5 0.54936
EXO1 exonuclease 1 0.458803
TOP3A topoisomerase (DNA) III alpha 0.419252
RAD52 RAD52 homolog (S. cerevisiae) 0.328708
ATM ATM serine/threonine kinase 0.32195
MLH1 mutL homolog 1 0.239197
CHEK1 checkpoint kinase 1 0.190495
PLK1 polo-like kinase 1 0.171149