smad6 Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description SMAD family member 6|The protein encoded by this gene belongs to the SMAD family of proteins, which are related to Drosophila 'mothers against decapentaplegic' (Mad) and C. elegans Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein functions in the negative regulation of BMP and TGF-beta/activin-signalling. Multiple transcript variants have been found for this gene.[provided by RefSeq, Sep 2014] (NCBI Entrez Gene Database, 4091)
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Genes

22 genes co-occuring with the biological term smad6 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
BMP4 bone morphogenetic protein 4
BMP7 bone morphogenetic protein 7
CTBP1 C-terminal binding protein 1
DLX3 distal-less homeobox 3
HDAC3 histone deacetylase 3
IL1B interleukin 1, beta
OAZ1 ornithine decarboxylase antizyme 1
PELI1 pellino E3 ubiquitin protein ligase 1
PROC protein C (inactivator of coagulation factors Va and VIIIa)
RUNX1 runt-related transcription factor 1
RUNX2 runt-related transcription factor 2
SMAD1 SMAD family member 1
SMAD2 SMAD family member 2
SMAD5 SMAD family member 5
SMAD6 SMAD family member 6
SMAD7 SMAD family member 7
SMURF1 SMAD specific E3 ubiquitin protein ligase 1
TGFB1 transforming growth factor, beta 1
TGFBR1 transforming growth factor, beta receptor 1
THBD thrombomodulin
TNF tumor necrosis factor
UBE2O ubiquitin-conjugating enzyme E2O