small GTPase binding Gene Set

Dataset GO Molecular Function Annotations 2023
Category structural or functional annotations
Type biological process
Description Interacting selectively and non-covalently with a small monomeric GTPase. (Gene Ontology, GO_0031267)
External Link http://amigo.geneontology.org/amigo/term/GO:0031267
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Genes

200 genes performing the small GTPase binding molecular function from the curated GO Molecular Function Annotations 2023 dataset.

Symbol Name
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1
ABI2 abl-interactor 2
AFD1 acrofacial dysostosis 1, Nager type
AKAP13 A kinase (PRKA) anchor protein 13
ALS2 amyotrophic lateral sclerosis 2 (juvenile)
ALS2CL ALS2 C-terminal like
ANKFY1 ankyrin repeat and FYVE domain containing 1
ANKRD27 ankyrin repeat domain 27 (VPS9 domain)
AP1G1 adaptor-related protein complex 1, gamma 1 subunit
AP3M1 adaptor-related protein complex 3, mu 1 subunit
ARFIP2 ADP-ribosylation factor interacting protein 2
ARHGAP1 Rho GTPase activating protein 1
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta
ARHGEF16 Rho guanine nucleotide exchange factor (GEF) 16
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2
ASB15 ankyrin repeat and SOCS box containing 15
ATP6AP1 ATPase, H+ transporting, lysosomal accessory protein 1
BICD1 bicaudal D homolog 1 (Drosophila)
BICD2 bicaudal D homolog 2 (Drosophila)
BIRC5 baculoviral IAP repeat containing 5
BRAF B-Raf proto-oncogene, serine/threonine kinase
BRK1 BRICK1, SCAR/WAVE actin-nucleating complex subunit
C15ORF62 chromosome 15 open reading frame 62
C9ORF72 chromosome 9 open reading frame 72
CAV1 caveolin 1, caveolae protein, 22kDa
CCDC186 coiled-coil domain containing 186
CCDC64 coiled-coil domain containing 64
CDC42EP1 CDC42 effector protein (Rho GTPase binding) 1
CDC42EP2 CDC42 effector protein (Rho GTPase binding) 2
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3
CDC42EP4 CDC42 effector protein (Rho GTPase binding) 4
CDC42EP5 CDC42 effector protein (Rho GTPase binding) 5
CDKL5 cyclin-dependent kinase-like 5
CHM choroideremia (Rab escort protein 1)
CHML choroideremia-like (Rab escort protein 2)
CIB1 calcium and integrin binding 1 (calmyrin)
CYFIP1 cytoplasmic FMR1 interacting protein 1
CYRIB CYFIP related Rac1 interactor B
DAPK3 death-associated protein kinase 3
DENND10 DENN domain containing 10
DENND5A DENN/MADD domain containing 5A
DENND5B DENN/MADD domain containing 5B
DMXL2 Dmx-like 2
DNM1L dynamin 1-like
DOCK1 dedicator of cytokinesis 1
DOCK2 dedicator of cytokinesis 2
DOCK3 dedicator of cytokinesis 3
DOCK4 dedicator of cytokinesis 4
DOCK5 dedicator of cytokinesis 5
DOCK7 dedicator of cytokinesis 7
DVL3 dishevelled segment polarity protein 3
EHD1 EH-domain containing 1
EPS8 epidermal growth factor receptor pathway substrate 8
ERC1 ELKS/RAB6-interacting/CAST family member 1
EVI5 ecotropic viral integration site 5
EVI5L ecotropic viral integration site 5-like
EXOC2 exocyst complex component 2
EXOC5 exocyst complex component 5
EXOC8 exocyst complex component 8
EXPH5 exophilin 5
FAM45B family with sequence similarity 45, member A pseudogene
FGD1 FYVE, RhoGEF and PH domain containing 1
FGD3 FYVE, RhoGEF and PH domain containing 3
FGD4 FYVE, RhoGEF and PH domain containing 4
FGD5 FYVE, RhoGEF and PH domain containing 5
FGD6 FYVE, RhoGEF and PH domain containing 6
FLNA filamin A, alpha
FMNL1 formin-like 1
GAPVD1 GTPase activating protein and VPS9 domains 1
GCC1 GRIP and coiled-coil domain containing 1
GCC2 GRIP and coiled-coil domain containing 2
GGA1 golgi-associated, gamma adaptin ear containing, ARF binding protein 1
GGA2 golgi-associated, gamma adaptin ear containing, ARF binding protein 2
GGA3 golgi-associated, gamma adaptin ear containing, ARF binding protein 3
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GIT2 G protein-coupled receptor kinase interacting ArfGAP 2
GOLGA4 golgin A4
GOLGA5 golgin A5
HACE1 HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1
HPS4 Hermansky-Pudlak syndrome 4
HPS6 Hermansky-Pudlak syndrome 6
IFT20 intraflagellar transport 20
IQGAP1 IQ motif containing GTPase activating protein 1
IQGAP2 IQ motif containing GTPase activating protein 2
KCTD13 potassium channel tetramerization domain containing 13
KIAA0355 KIAA0355
KIF3A kinesin family member 3A
KIF3B kinesin family member 3B
KNTC1 kinetochore associated 1
LRRK2 leucine-rich repeat kinase 2
LSM2 LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae)
LZTR1 leucine-zipper-like transcription regulator 1
MAPKAP1 mitogen-activated protein kinase associated protein 1
MEGF9 multiple EGF-like-domains 9
MICALL1 MICAL-like 1
MLPH melanophilin
MRAP melanocortin 2 receptor accessory protein
MTSS2 MTSS I-BAR domain containing 2
MYCBP2 MYC binding protein 2, E3 ubiquitin protein ligase
MYO1C myosin IC
MYO5A myosin VA (heavy chain 12, myoxin)
MYO5B myosin VB
MYO9B myosin IXB
NCKAP1 NCK-associated protein 1
NDRG1 N-myc downstream regulated 1
NGFR nerve growth factor receptor
NOX1 NADPH oxidase 1
NOXA1 NADPH oxidase activator 1
NPC1L1 NPC1-like 1
NUTF2 nuclear transport factor 2
OCRL oculocerebrorenal syndrome of Lowe
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1
PAK2 p21 protein (Cdc42/Rac)-activated kinase 2
PARD6A par-6 family cell polarity regulator alpha
PDE6D phosphodiesterase 6D, cGMP-specific, rod, delta
PEX5 peroxisomal biogenesis factor 5
PEX5L peroxisomal biogenesis factor 5-like
PICALM phosphatidylinositol binding clathrin assembly protein
PIFO primary cilia formation
PIH1D2 PIH1 domain containing 2
PKN1 protein kinase N1
PLCE1 phospholipase C, epsilon 1
PLEKHG1 pleckstrin homology domain containing, family G (with RhoGef domain) member 1
PLEKHG2 pleckstrin homology domain containing, family G (with RhoGef domain) member 2
PLEKHG3 pleckstrin homology domain containing, family G (with RhoGef domain) member 3
PPP6R1 protein phosphatase 6, regulatory subunit 1
RAB11FIP3 RAB11 family interacting protein 3 (class II)
RAB11FIP4 RAB11 family interacting protein 4 (class II)
RAB29 RAB29, member RAS oncogene family
RAB34 RAB34, member RAS oncogene family
RAB3GAP1 RAB3 GTPase activating protein subunit 1 (catalytic)
RAB3GAP2 RAB3 GTPase activating protein subunit 2 (non-catalytic)
RAB8A RAB8A, member RAS oncogene family
RABGAP1 RAB GTPase activating protein 1
RABGAP1L RAB GTPase activating protein 1-like
RABGEF1 RAB guanine nucleotide exchange factor (GEF) 1
RABGGTA Rab geranylgeranyltransferase, alpha subunit
RABGGTB Rab geranylgeranyltransferase, beta subunit
RAF1 Raf-1 proto-oncogene, serine/threonine kinase
RALBP1 ralA binding protein 1
RANBP1 RAN binding protein 1
RANBP2 RAN binding protein 2
RANBP9 RAN binding protein 9
RANGAP1 Ran GTPase activating protein 1
RANGRF RAN guanine nucleotide release factor
RAP1GAP RAP1 GTPase activating protein
RAPGEF4 Rap guanine nucleotide exchange factor (GEF) 4
RAPGEF6 Rap guanine nucleotide exchange factor (GEF) 6
RCC1 regulator of chromosome condensation 1
RCC2 regulator of chromosome condensation 2
RGP1 RGP1 retrograde golgi transport homolog (S. cerevisiae)
RGPD8 RANBP2-like and GRIP domain containing 8
RHOBTB3 Rho-related BTB domain containing 3
RHOH ras homolog family member H
RIC1 RAB6A GEF complex partner 1
RILP Rab interacting lysosomal protein
RILPL1 Rab interacting lysosomal protein-like 1
RILPL2 Rab interacting lysosomal protein-like 2
RIMS1 regulating synaptic membrane exocytosis 1
RIN1 Ras and Rab interactor 1
RIN2 Ras and Rab interactor 2
RIN3 Ras and Rab interactor 3
RINL Ras and Rab interactor-like
RNF152 ring finger protein 152
RNF41 ring finger protein 41, E3 ubiquitin protein ligase
RTKN rhotekin
RUSC2 RUN and SH3 domain containing 2
SGSM1 small G protein signaling modulator 1
SGSM2 small G protein signaling modulator 2
SGSM3 small G protein signaling modulator 3
SH3BP4 SH3-domain binding protein 4
SIKE1 suppressor of IKBKE 1
SOD1 superoxide dismutase 1, soluble
SORL1 sortilin-related receptor, L(DLR class) A repeats containing
SPHK2 sphingosine kinase 2
SRGAP3 SLIT-ROBO Rho GTPase activating protein 3
STK19 serine/threonine kinase 19
STRN3 striatin, calmodulin binding protein 3
TBC1D20 TBC1 domain family, member 20
TBC1D21 TBC1 domain family, member 21
TBC1D30 TBC1 domain family, member 30
TBC1D7 TBC1 domain family, member 7
TMEM127 transmembrane protein 127
TNFAIP1 tumor necrosis factor, alpha-induced protein 1 (endothelial)
TNPO3 transportin 3
TRIOBP TRIO and F-actin binding protein
TRIP11 thyroid hormone receptor interactor 11
TSC2 tuberous sclerosis 2
ULK1 unc-51 like autophagy activating kinase 1
UNC13B unc-13 homolog B (C. elegans)
UNC13D unc-13 homolog D (C. elegans)
USP33 ubiquitin specific peptidase 33
USP6NL USP6 N-terminal like
VPS9D1 VPS9 domain containing 1
WAS Wiskott-Aldrich syndrome
WASF1 WAS protein family, member 1
WHAMM WAS protein homolog associated with actin, golgi membranes and microtubules
XPO4 exportin 4
XPO5 exportin 5
YBX3 Y box binding protein 3