small embryonic epiblast Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description reduced size of the transient structure derived from the inner cell mass which lies above the hypoblast; the epiblast tissue gives rise to the three primary germ layers (ectoderm, definitive endoderm, and mesoderm) and to the extraembryonic mesoderm of the visceral yolk sac, the allantois, and the amnion (Mammalian Phenotype Ontology, MP_0011189)
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7 gene mutations causing the small embryonic epiblast phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ATAD3A ATPase family, AAA domain containing 3A
FOXD3 forkhead box D3
GATA6 GATA binding protein 6
MESDC2 mesoderm development candidate 2
SALL4 spalt-like transcription factor 4
TAF10 TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 30kDa
TFAP2C transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)