small floor plate Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description reduced size of the specialized glial structure (non-neuronal cells) situated at the ventral midline of the embryonic neural tube; this structure spans the anteroposterior axis from the midbrain to the tail regions, separating the left and right basal plates of the developing neural tube, and serves as an organizer to ventralize tissues in the embryo as well as to guide neuronal positioning and differentiation along the dorsoventral axis of the neural tube (Mammalian Phenotype Ontology, MP_0000927)
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3 gene mutations causing the small floor plate phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
FUZ fuzzy planar cell polarity protein
INTU inturned planar cell polarity protein
RFX4 regulatory factor X, 4 (influences HLA class II expression)