SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1|The protein encoded by this gene is part of a complex that relieves repressive chromatin structures, allowing the transcriptional machinery to access its targets more effectively. The encoded nuclear protein may also bind to and enhance the DNA joining activity of HIV-1 integrase. This gene has been found to be a tumor suppressor, and mutations in it have been associated with malignant rhabdoid tumors. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 6598)
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11 genes co-occuring with the biological term smarcb1 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.
