smc5-smc6 complex Gene Set

Dataset COMPARTMENTS Curated Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description A conserved complex that contains a heterodimer of SMC proteins (Smc5p and Smc6p, or homologs thereof) and several other proteins, and is involved in DNA repair and maintaining cell cycle arrest following DNA damage. In S. cerevisiae, this is an octameric complex called Mms21-Smc5-Smc6 complex, with at least five of its subunits conserved in fission yeast and humans. (Gene Ontology, GO_0030915)
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6 proteins localized to the smc5-smc6 complex cellular component from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
NDNL2 necdin-like 2 0.663342
NSMCE1 non-SMC element 1 homolog (S. cerevisiae) 0.663342
NSMCE2 non-SMC element 2, MMS21 homolog (S. cerevisiae) 0.663342
SMC5 structural maintenance of chromosomes 5 0.663342
SMC6 structural maintenance of chromosomes 6 0.663342
NSMCE4A non-SMC element 4 homolog A (S. cerevisiae) 0.663342