smokers Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
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Genes

282 genes co-occuring with the biological term smokers in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ABCG5 ATP-binding cassette, sub-family G (WHITE), member 5
ABCG8 ATP-binding cassette, sub-family G (WHITE), member 8
ACE angiotensin I converting enzyme
ADAM33 ADAM metallopeptidase domain 33
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
ADIPOQ adiponectin, C1Q and collagen domain containing
ADM adrenomedullin
ADRA2A adrenoceptor alpha 2A
ADRB2 adrenoceptor beta 2, surface
AGER advanced glycosylation end product-specific receptor
AHR aryl hydrocarbon receptor
AIMP1 aminoacyl tRNA synthetase complex-interacting multifunctional protein 1
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
ALK anaplastic lymphoma receptor tyrosine kinase
ALOX5AP arachidonate 5-lipoxygenase-activating protein
ANKK1 ankyrin repeat and kinase domain containing 1
ANKS1B ankyrin repeat and sterile alpha motif domain containing 1B
APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1
APOE apolipoprotein E
ATF4 activating transcription factor 4
ATG16L1 autophagy related 16-like 1 (S. cerevisiae)
ATM ATM serine/threonine kinase
ATP4A ATPase, H+/K+ exchanging, alpha polypeptide
AZGP1 alpha-2-glycoprotein 1, zinc-binding
B3GAT1 beta-1,3-glucuronyltransferase 1
BAX BCL2-associated X protein
BCL2 B-cell CLL/lymphoma 2
BCL2L1 BCL2-like 1
BDNF brain-derived neurotrophic factor
BIRC5 baculoviral IAP repeat containing 5
BLVRA biliverdin reductase A
BPI bactericidal/permeability-increasing protein
BRAF B-Raf proto-oncogene, serine/threonine kinase
BRCA1 breast cancer 1, early onset
BRCA2 breast cancer 2, early onset
C3 complement component 3
CAMP cathelicidin antimicrobial peptide
CAPN10 calpain 10
CASC5 cancer susceptibility candidate 5
CAT catalase
CBS cystathionine-beta-synthase
CCND1 cyclin D1
CD14 CD14 molecule
CD36 CD36 molecule (thrombospondin receptor)
CD40LG CD40 ligand
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN2A cyclin-dependent kinase inhibitor 2A
CETP cholesteryl ester transfer protein, plasma
CGB chorionic gonadotropin, beta polypeptide
CHAT choline O-acetyltransferase
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CHIT1 chitinase 1 (chitotriosidase)
CHRFAM7A CHRNA7 (cholinergic receptor, nicotinic, alpha 7, exons 5-10) and FAM7A (family with sequence similarity 7A, exons A-E) fusion
CHRNA2 cholinergic receptor, nicotinic, alpha 2 (neuronal)
CHRNA3 cholinergic receptor, nicotinic, alpha 3 (neuronal)
CHRNA4 cholinergic receptor, nicotinic, alpha 4 (neuronal)
CHRNA5 cholinergic receptor, nicotinic, alpha 5 (neuronal)
CHRNA6 cholinergic receptor, nicotinic, alpha 6 (neuronal)
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal)
CHRNB3 cholinergic receptor, nicotinic, beta 3 (neuronal)
CHRNB4 cholinergic receptor, nicotinic, beta 4 (neuronal)
CLCA1 chloride channel accessory 1
COMT catechol-O-methyltransferase
CREB1 cAMP responsive element binding protein 1
CRHBP corticotropin releasing hormone binding protein
CRP C-reactive protein, pentraxin-related
CRYAB crystallin, alpha B
CRYGD crystallin, gamma D
CSF3 colony stimulating factor 3 (granulocyte)
CX3CR1 chemokine (C-X3-C motif) receptor 1
CXCL10 chemokine (C-X-C motif) ligand 10
CXCL8 chemokine (C-X-C motif) ligand 8
CXCR1 chemokine (C-X-C motif) receptor 1
CXCR3 chemokine (C-X-C motif) receptor 3
CYBA cytochrome b-245, alpha polypeptide
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
CYP2A13 cytochrome P450, family 2, subfamily A, polypeptide 13
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5
DBH dopamine beta-hydroxylase (dopamine beta-monooxygenase)
DDC dopa decarboxylase (aromatic L-amino acid decarboxylase)
DEFB4A defensin, beta 4A
DLG4 discs, large homolog 4 (Drosophila)
DNMT1 DNA (cytosine-5-)-methyltransferase 1
DRD2 dopamine receptor D2
DRD3 dopamine receptor D3
DRD4 dopamine receptor D4
EDN1 endothelin 1
EGF epidermal growth factor
EGFR epidermal growth factor receptor
ERBB2 erb-b2 receptor tyrosine kinase 2
ERCC1 excision repair cross-complementation group 1
ERCC2 excision repair cross-complementation group 2
ERCC5 excision repair cross-complementation group 5
ESR2 estrogen receptor 2 (ER beta)
FAM13A family with sequence similarity 13, member A
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32)
FGB fibrinogen beta chain
FLT1 fms-related tyrosine kinase 1
FOXO3 forkhead box O3
FOXP3 forkhead box P3
FSHR follicle stimulating hormone receptor
FTMT ferritin mitochondrial
GABARAP GABA(A) receptor-associated protein
GALR1 galanin receptor 1
GHRL ghrelin/obestatin prepropeptide
GPC5 glypican 5
GPX1 glutathione peroxidase 1
GSTA1 glutathione S-transferase alpha 1
GSTM1 glutathione S-transferase mu 1
GSTM2 glutathione S-transferase mu 2 (muscle)
GSTO2 glutathione S-transferase omega 2
GSTP1 glutathione S-transferase pi 1
GSTT1 glutathione S-transferase theta 1
HCRT hypocretin (orexin) neuropeptide precursor
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HLA-G major histocompatibility complex, class I, G
HMOX1 heme oxygenase 1
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1
HP haptoglobin
HPRT1 hypoxanthine phosphoribosyltransferase 1
HSPB1 heat shock 27kDa protein 1
HTR1A 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled
HTR2A 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
HTR3B 5-hydroxytryptamine (serotonin) receptor 3B, ionotropic
ICAM1 intercellular adhesion molecule 1
IFNG interferon, gamma
IFNGR1 interferon gamma receptor 1
IFNGR2 interferon gamma receptor 2 (interferon gamma transducer 1)
IGF1 insulin-like growth factor 1 (somatomedin C)
IGF2 insulin-like growth factor 2
IGFBP3 insulin-like growth factor binding protein 3
IGHMBP2 immunoglobulin mu binding protein 2
IL10 interleukin 10
IL13 interleukin 13
IL13RA1 interleukin 13 receptor, alpha 1
IL15 interleukin 15
IL17A interleukin 17A
IL18 interleukin 18
IL1RN interleukin 1 receptor antagonist
IL2 interleukin 2
IL4 interleukin 4
IL4R interleukin 4 receptor
IL6 interleukin 6
IREB2 iron-responsive element binding protein 2
IRF7 interferon regulatory factor 7
IRS1 insulin receptor substrate 1
JAK2 Janus kinase 2
KDR kinase insert domain receptor
KLRK1 killer cell lectin-like receptor subfamily K, member 1
KRAS Kirsten rat sarcoma viral oncogene homolog
L1TD1 LINE-1 type transposase domain containing 1
LBP lipopolysaccharide binding protein
LEPR leptin receptor
LPL lipoprotein lipase
LTB4R leukotriene B4 receptor
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MAGEA4 melanoma antigen family A4
MAOA monoamine oxidase A
MAOB monoamine oxidase B
MAPK1 mitogen-activated protein kinase 1
MAPK3 mitogen-activated protein kinase 3
MAPK7 mitogen-activated protein kinase 7
MBL2 mannose-binding lectin (protein C) 2, soluble
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MERTK MER proto-oncogene, tyrosine kinase
MET MET proto-oncogene, receptor tyrosine kinase
MGMT O-6-methylguanine-DNA methyltransferase
MIR149 microRNA 149
MIR181A1 microRNA 181a-1
MIR199A1 microRNA 199a-1
MIR199A2 microRNA 199a-2
MIR21 microRNA 21
MIR605 microRNA 605
MKI67 marker of proliferation Ki-67
MLH1 mutL homolog 1
MMP1 matrix metallopeptidase 1
MMP12 matrix metallopeptidase 12
MMP2 matrix metallopeptidase 2
MMP3 matrix metallopeptidase 3
MMP8 matrix metallopeptidase 8
MMP9 matrix metallopeptidase 9
MPO myeloperoxidase
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MTRR 5-methyltetrahydrofolate-homocysteine methyltransferase reductase
MUC5AC mucin 5AC, oligomeric mucus/gel-forming
MUC5B mucin 5B, oligomeric mucus/gel-forming
NAT1 N-acetyltransferase 1 (arylamine N-acetyltransferase)
NAT2 N-acetyltransferase 2 (arylamine N-acetyltransferase)
NFE2L2 nuclear factor, erythroid 2-like 2
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NOS3 nitric oxide synthase 3 (endothelial cell)
NPPB natriuretic peptide B
NQO1 NAD(P)H dehydrogenase, quinone 1
NR1H3 nuclear receptor subfamily 1, group H, member 3
NR1I2 nuclear receptor subfamily 1, group I, member 2
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
NR4A2 nuclear receptor subfamily 4, group A, member 2
OGG1 8-oxoguanine DNA glycosylase
OPRM1 opioid receptor, mu 1
P2RX7 purinergic receptor P2X, ligand gated ion channel, 7
P2RY12 purinergic receptor P2Y, G-protein coupled, 12
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I
PADI4 peptidyl arginine deiminase, type IV
PAPPA pregnancy-associated plasma protein A, pappalysin 1
PDE4A phosphodiesterase 4A, cAMP-specific
PDGFRB platelet-derived growth factor receptor, beta polypeptide
PGF placental growth factor
PIGR polymeric immunoglobulin receptor
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
PLA2G7 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
PLAUR plasminogen activator, urokinase receptor
PON1 paraoxonase 1
PPARG peroxisome proliferator-activated receptor gamma
PPIA peptidylprolyl isomerase A (cyclophilin A)
PRKCA protein kinase C, alpha
PRKDC protein kinase, DNA-activated, catalytic polypeptide
PRSS1 protease, serine, 1 (trypsin 1)
PTAFR platelet-activating factor receptor
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
RAP1A RAP1A, member of RAS oncogene family
RARB retinoic acid receptor, beta
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
RORC RAR-related orphan receptor C
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SFRP2 secreted frizzled-related protein 2
SFTPB surfactant protein B
SFTPD surfactant protein D
SIRT1 sirtuin 1
SLC18A2 solute carrier family 18 (vesicular monoamine transporter), member 2
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4
SOD2 superoxide dismutase 2, mitochondrial
SOD3 superoxide dismutase 3, extracellular
SPP1 secreted phosphoprotein 1
SRXN1 sulfiredoxin 1
STK11 serine/threonine kinase 11
SULT1A1 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
SUV39H2 suppressor of variegation 3-9 homolog 2 (Drosophila)
SYTL1 synaptotagmin-like 1
TERT telomerase reverse transcriptase
TF transferrin
TGFB1 transforming growth factor, beta 1
TIMP1 TIMP metallopeptidase inhibitor 1
TIMP2 TIMP metallopeptidase inhibitor 2
TLR2 toll-like receptor 2
TLR3 toll-like receptor 3
TLR4 toll-like receptor 4
TLR5 toll-like receptor 5
TLR9 toll-like receptor 9
TNF tumor necrosis factor
TNFRSF11A tumor necrosis factor receptor superfamily, member 11a, NFKB activator
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11
TP53 tumor protein p53
TP73 tumor protein p73
TPH1 tryptophan hydroxylase 1
TREM1 triggering receptor expressed on myeloid cells 1
TRPA1 transient receptor potential cation channel, subfamily A, member 1
TRPV1 transient receptor potential cation channel, subfamily V, member 1
TTC12 tetratricopeptide repeat domain 12
TTF1 transcription termination factor, RNA polymerase I
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
UGT1A7 UDP glucuronosyltransferase 1 family, polypeptide A7
UGT2B10 UDP glucuronosyltransferase 2 family, polypeptide B10
UGT2B17 UDP glucuronosyltransferase 2 family, polypeptide B17
VASP vasodilator-stimulated phosphoprotein
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
XPC xeroderma pigmentosum, complementation group C
XRCC1 X-ray repair complementing defective repair in Chinese hamster cells 1
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3