smooth endoplasmic reticulum Gene Set

Dataset GO Cellular Component Annotations
Category structural or functional annotations
Type cellular component
Description The smooth endoplasmic reticulum (smooth ER or SER) has no ribosomes attached to it. The smooth ER is the recipient of the proteins synthesized in the rough ER. Those proteins to be exported are passed to the Golgi complex, the resident proteins are returned to the rough ER and the lysosomal proteins after phosphorylation of their mannose residues are passed to the lysosomes. Glycosylation of the glycoproteins also continues. The smooth ER is the site of synthesis of lipids, including the phospholipids. The membranes of the smooth ER also contain enzymes that catalyze a series of reactions to detoxify both lipid-soluble drugs and harmful products of metabolism. Large quantities of certain compounds such as phenobarbital cause an increase in the amount of the smooth ER. (Gene Ontology, GO_0005790)
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24 proteins localized to the smooth endoplasmic reticulum cellular component from the curated GO Cellular Component Annotations dataset.

Symbol Name
CALR calreticulin
CANX calnexin
CASQ1 calsequestrin 1 (fast-twitch, skeletal muscle)
DNAJC3 DnaJ (Hsp40) homolog, subfamily C, member 3
ERP29 endoplasmic reticulum protein 29
GABARAP GABA(A) receptor-associated protein
GBA2 glucosidase, beta (bile acid) 2
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
HYOU1 hypoxia up-regulated 1
JPH4 junctophilin 4
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2
KCNN2 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2
MAPK8IP3 mitogen-activated protein kinase 8 interacting protein 3
MYO1D myosin ID
PDIA3 protein disulfide isomerase family A, member 3
PLCB4 phospholipase C, beta 4
PPIB peptidylprolyl isomerase B (cyclophilin B)
PRDX4 peroxiredoxin 4
PSEN1 presenilin 1
RYR1 ryanodine receptor 1 (skeletal)
RYR2 ryanodine receptor 2 (cardiac)
SLMAP sarcolemma associated protein
SRI sorcin
TH tyrosine hydroxylase