smurf1 Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description SMAD specific E3 ubiquitin protein ligase 1|This gene encodes a ubiquitin ligase that is specific for receptor-regulated SMAD proteins in the bone morphogenetic protein (BMP) pathway. This protein plays a key roll in the regulation of cell motility, cell signalling, and cell polarity. Alternative splicing results in multiple transcript variants encoding different isoforms.[provided by RefSeq, Dec 2010] (NCBI Entrez Gene Database, 57154)
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Genes

28 genes co-occuring with the biological term smurf1 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ARHGAP32 Rho GTPase activating protein 32
ARHGEF9 Cdc42 guanine nucleotide exchange factor (GEF) 9
BTRC beta-transducin repeat containing E3 ubiquitin protein ligase
CCM2 cerebral cavernous malformation 2
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
FBXO32 F-box protein 32
FSTL3 follistatin-like 3 (secreted glycoprotein)
IFNG interferon, gamma
KLF2 Kruppel-like factor 2
MIR17 microRNA 17
MIR497 microRNA 497
MSTN myostatin
PDLIM7 PDZ and LIM domain 7 (enigma)
PLEKHO1 pleckstrin homology domain containing, family O member 1
PSMC5 proteasome (prosome, macropain) 26S subunit, ATPase, 5
RFWD2 ring finger and WD repeat domain 2, E3 ubiquitin protein ligase
RHOA ras homolog family member A
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1
SMAD1 SMAD family member 1
SMAD5 SMAD family member 5
SMAD7 SMAD family member 7
SMURF1 SMAD specific E3 ubiquitin protein ligase 1
SMURF2 SMAD specific E3 ubiquitin protein ligase 2
TRAF4 TNF receptor-associated factor 4
TRIB2 tribbles pseudokinase 2
USP9X ubiquitin specific peptidase 9, X-linked
WFS1 Wolfram syndrome 1 (wolframin)
XPO1 exportin 1