sorting nexin 1|This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This endosomal protein regulates the cell-surface expression of epidermal growth factor receptor. This protein also has a role in sorting protease-activated receptor-1 from early endosomes to lysosomes. This protein may form oligomeric complexes with family members. This gene results in three transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 6642)
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14 genes co-occuring with the biological term snx1 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.
