socs6 Gene Set

Dataset	GeneRIF Biological Term Annotations
Category	structural or functional annotations
Type	biological term
Description	suppressor of cytokine signaling 6\|The protein encoded by this gene contains a SH2 domain and a CIS homolog domain. The protein thus belongs to the cytokine-induced STAT inhibitor (CIS), also known as suppressor of cytokine signaling (SOCS) or STAT-induced STAT inhibitor (SSI), protein family. CIS family members are known to be cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by GM-CSF and EPO in hematopoietic cells. A high expression level of this gene was found in factor-independent chronic myelogenous leukemia (CML) and erythroleukemia (HEL) cell lines. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 9306)
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Genes

11 genes co-occuring with the biological term socs6 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol	Name
BCAR1	breast cancer anti-estrogen resistance 1
DNM1L	dynamin 1-like
FLT3	fms-related tyrosine kinase 3
KIT	v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
MIR17	microRNA 17
PRKCD	protein kinase C, delta
RBCK1	RanBP-type and C3HC4-type zinc finger containing 1
SOCS2	suppressor of cytokine signaling 2
SOCS5	suppressor of cytokine signaling 5
SOCS6	suppressor of cytokine signaling 6
STAT3	signal transducer and activator of transcription 3 (acute-phase response factor)