sod1 Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description superoxide dismutase 1, soluble|The protein encoded by this gene binds copper and zinc ions and is one of two isozymes responsible for destroying free superoxide radicals in the body. The encoded isozyme is a soluble cytoplasmic protein, acting as a homodimer to convert naturally-occuring but harmful superoxide radicals to molecular oxygen and hydrogen peroxide. The other isozyme is a mitochondrial protein. Mutations in this gene have been implicated as causes of familial amyotrophic lateral sclerosis. Rare transcript variants have been reported for this gene. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 6647)
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Genes

74 genes co-occuring with the biological term sod1 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
AKT3 v-akt murine thymoma viral oncogene homolog 3
ALOX5 arachidonate 5-lipoxygenase
ALS2 amyotrophic lateral sclerosis 2 (juvenile)
AMFR autocrine motility factor receptor, E3 ubiquitin protein ligase
ANG angiogenin, ribonuclease, RNase A family, 5
APP amyloid beta (A4) precursor protein
ATXN3 ataxin 3
BACE1 beta-site APP-cleaving enzyme 1
BAX BCL2-associated X protein
BCL2 B-cell CLL/lymphoma 2
CAT catalase
CCS copper chaperone for superoxide dismutase
CHRM1 cholinergic receptor, muscarinic 1
CNTF ciliary neurotrophic factor
COMMD1 copper metabolism (Murr1) domain containing 1
COQ7 coenzyme Q7 homolog, ubiquinone (yeast)
CP ceruloplasmin (ferroxidase)
CRYAB crystallin, alpha B
CSTB cystatin B (stefin B)
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2
DVL1 dishevelled segment polarity protein 1
ELAVL1 ELAV like RNA binding protein 1
ELK1 ELK1, member of ETS oncogene family
EPHA3 EPH receptor A3
ERVW-1 endogenous retrovirus group W, member 1
FAS Fas cell surface death receptor
FGF2 fibroblast growth factor 2 (basic)
FMO1 flavin containing monooxygenase 1
FUS FUS RNA binding protein
GPX1 glutathione peroxidase 1
GSTP1 glutathione S-transferase pi 1
HECW1 HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1
HFE hemochromatosis
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase
HSPA4L heat shock 70kDa protein 4-like
HSPB1 heat shock 27kDa protein 1
HSPB2 heat shock 27kDa protein 2
HSPB8 heat shock 22kDa protein 8
HTR1A 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled
IL17A interleukin 17A
IRAK3 interleukin-1 receptor-associated kinase 3
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
KARS lysyl-tRNA synthetase
KIF1B kinesin family member 1B
KIF3A kinesin family member 3A
KIFAP3 kinesin-associated protein 3
LOC643387 TAR DNA binding protein pseudogene
MAPT microtubule-associated protein tau
NCF2 neutrophil cytosolic factor 2
NEFL neurofilament, light polypeptide
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
P4HB prolyl 4-hydroxylase, beta polypeptide
PARK7 parkinson protein 7
PRDX2 peroxiredoxin 2
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
RAD54B RAD54 homolog B (S. cerevisiae)
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase
S100A6 S100 calcium binding protein A6
SELP selectin P (granule membrane protein 140kDa, antigen CD62)
SIRT5 sirtuin 5
SOD1 superoxide dismutase 1, soluble
SOD2 superoxide dismutase 2, mitochondrial
SOD3 superoxide dismutase 3, extracellular
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
SRR serine racemase
STAT1 signal transducer and activator of transcription 1, 91kDa
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase
TARDBP TAR DNA binding protein
TIAL1 TIA1 cytotoxic granule-associated RNA binding protein-like 1
UCP2 uncoupling protein 2 (mitochondrial, proton carrier)
VAPB VAMP (vesicle-associated membrane protein)-associated protein B and C
VEGFA vascular endothelial growth factor A
VGF VGF nerve growth factor inducible
VSX1 visual system homeobox 1