sodium-phenylacetate Gene Set

Dataset LINCS L1000 CMAP Chemical Perturbation Consensus Signatures
Category transcriptomics
Type small molecule perturbation
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Genes

689 genes differentially expressed following the sodium-phenylacetate small molecule perturbation from the LINCS L1000 CMAP Chemical Perturbation Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
STAT1 signal transducer and activator of transcription 1, 91kDa 8.19306
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4 6.90038
FAM124B family with sequence similarity 124B 6.63267
TDRKH tudor and KH domain containing 6.53551
PDE7B phosphodiesterase 7B 5.95553
PRKCH protein kinase C, eta 5.86128
PDCD1 programmed cell death 1 5.83822
RPL6 ribosomal protein L6 5.66262
PRDX4 peroxiredoxin 4 5.6433
CACNA1B calcium channel, voltage-dependent, N type, alpha 1B subunit 5.59566
HS2ST1 heparan sulfate 2-O-sulfotransferase 1 5.58149
WFDC8 WAP four-disulfide core domain 8 5.52546
MEF2C myocyte enhancer factor 2C 5.48721
BMP6 bone morphogenetic protein 6 5.41421
KCNC3 potassium channel, voltage gated Shaw related subfamily C, member 3 5.2604
MOK MOK protein kinase 5.23659
INSRR insulin receptor-related receptor 5.17637
VIPAS39 VPS33B interacting protein, apical-basolateral polarity regulator, spe-39 homolog 5.11479
VNN1 vanin 1 5.05535
NOS3 nitric oxide synthase 3 (endothelial cell) 5.01151
BPHL biphenyl hydrolase-like (serine hydrolase) 5.00319
KDELR3 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3 4.99336
ITGA9 integrin, alpha 9 4.9353
IGHMBP2 immunoglobulin mu binding protein 2 4.91123
SELL selectin L 4.87617
CRHR1 corticotropin releasing hormone receptor 1 4.87491
SLC22A6 solute carrier family 22 (organic anion transporter), member 6 4.8343
SLC44A1 solute carrier family 44 (choline transporter), member 1 4.83192
CAST calpastatin 4.79709
TPD52L2 tumor protein D52-like 2 4.79697
SLC22A7 solute carrier family 22 (organic anion transporter), member 7 4.78413
ITM2B integral membrane protein 2B 4.77085
PDIA5 protein disulfide isomerase family A, member 5 4.76437
UBA2 ubiquitin-like modifier activating enzyme 2 4.72784
WNT7A wingless-type MMTV integration site family, member 7A 4.67838
UPK2 uroplakin 2 4.66457
A4GALT alpha 1,4-galactosyltransferase 4.66093
COLEC11 collectin sub-family member 11 4.64583
GDF2 growth differentiation factor 2 4.62264
ALDH8A1 aldehyde dehydrogenase 8 family, member A1 4.62043
BTG2 BTG family, member 2 4.60692
ADAMTS8 ADAM metallopeptidase with thrombospondin type 1 motif, 8 4.56556
GPR50 G protein-coupled receptor 50 4.45502
CEP70 centrosomal protein 70kDa 4.4478
DNAI1 dynein, axonemal, intermediate chain 1 4.42182
PRODH proline dehydrogenase (oxidase) 1 4.41764
PLCH2 phospholipase C, eta 2 4.39779
NTN3 netrin 3 4.39416
MMP24 matrix metallopeptidase 24 (membrane-inserted) 4.37867
ABCD4 ATP-binding cassette, sub-family D (ALD), member 4 4.36648
CCR1 chemokine (C-C motif) receptor 1 4.35062
RBM34 RNA binding motif protein 34 4.3497
FBP1 fructose-1,6-bisphosphatase 1 4.34048
KCNV2 potassium channel, voltage gated modifier subfamily V, member 2 4.31409
PEPD peptidase D 4.30378
SGCA sarcoglycan, alpha (50kDa dystrophin-associated glycoprotein) 4.30114
NOX4 NADPH oxidase 4 4.29853
ZNF142 zinc finger protein 142 4.28968
FSHR follicle stimulating hormone receptor 4.28915
CDX4 caudal type homeobox 4 4.27527
TRPA1 transient receptor potential cation channel, subfamily A, member 1 4.27171
RBM8A RNA binding motif protein 8A 4.26406
FBLN5 fibulin 5 4.24617
NCF1C neutrophil cytosolic factor 1C pseudogene 4.24481
FNDC11 fibronectin type III domain containing 11 4.22324
KCNQ1DN KCNQ1 downstream neighbor (non-protein coding) 4.21828
PCYOX1 prenylcysteine oxidase 1 4.19998
HIP1 huntingtin interacting protein 1 4.18539
GBX2 gastrulation brain homeobox 2 4.18483
OGFOD2 2-oxoglutarate and iron-dependent oxygenase domain containing 2 4.17828
MRPS31 mitochondrial ribosomal protein S31 4.17123
ASH2L ash2 (absent, small, or homeotic)-like (Drosophila) 4.16895
TMEM183A transmembrane protein 183A 4.16447
TMED2 transmembrane emp24 domain trafficking protein 2 4.16354
TBCCD1 TBCC domain containing 1 4.16294
PAIP2B poly(A) binding protein interacting protein 2B 4.15901
CA5A carbonic anhydrase VA, mitochondrial 4.12598
PRKCD protein kinase C, delta 4.11563
ARHGEF9 Cdc42 guanine nucleotide exchange factor (GEF) 9 4.11283
SHB Src homology 2 domain containing adaptor protein B 4.1037
RPL4 ribosomal protein L4 4.08801
SOX18 SRY (sex determining region Y)-box 18 4.08766
COX16 COX16 cytochrome c oxidase assembly homolog (S. cerevisiae) 4.08629
ALX3 ALX homeobox 3 4.07746
ZP2 zona pellucida glycoprotein 2 (sperm receptor) 4.07702
NFIB nuclear factor I/B 4.0681
NOVA2 neuro-oncological ventral antigen 2 4.04198
REXO5 RNA exonuclease 5 4.03748
DVL3 dishevelled segment polarity protein 3 4.03018
DTNB dystrobrevin, beta 4.02898
RPL13A ribosomal protein L13a 4.02101
FLT4 fms-related tyrosine kinase 4 4.0145
PRKD3 protein kinase D3 4.0105
CCN5 cellular communication network factor 5 4.01048
PKLR pyruvate kinase, liver and RBC 3.99941
FAM222B family with sequence similarity 222, member B 3.99925
ZNF671 zinc finger protein 671 3.98679
TUBB4A tubulin, beta 4A class IVa 3.9816
HYDIN HYDIN, axonemal central pair apparatus protein 3.98121
NOL4 nucleolar protein 4 3.97858
FFAR3 free fatty acid receptor 3 3.97516
SLC13A1 solute carrier family 13 (sodium/sulfate symporter), member 1 3.9746
PIPOX pipecolic acid oxidase 3.95822
DHFR dihydrofolate reductase 3.95623
PDE6B phosphodiesterase 6B, cGMP-specific, rod, beta 3.95568
ABCC10 ATP-binding cassette, sub-family C (CFTR/MRP), member 10 3.95508
SDHAP1 succinate dehydrogenase complex, subunit A, flavoprotein pseudogene 1 3.94759
DRICH1 aspartate-rich 1 3.93808
SHROOM2 shroom family member 2 3.93516
GRIA4 glutamate receptor, ionotropic, AMPA 4 3.92862
RPL37A ribosomal protein L37a 3.92594
SAYSD1 SAYSVFN motif domain containing 1 3.92003
PTPRS protein tyrosine phosphatase, receptor type, S 3.91048
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2 3.90467
IL18BP interleukin 18 binding protein 3.89803
INA internexin neuronal intermediate filament protein, alpha 3.89405
C22ORF46P CTA-216E10.6 3.89131
TESPA1 thymocyte expressed, positive selection associated 1 3.88185
MTERF4 mitochondrial transcription termination factor 4 3.86592
KMT2D lysine (K)-specific methyltransferase 2D 3.85948
TSPAN9 tetraspanin 9 3.8559
CAB39L calcium binding protein 39-like 3.84414
LXN latexin 3.83752
PRKAG2 protein kinase, AMP-activated, gamma 2 non-catalytic subunit 3.8316
UPK1A uroplakin 1A 3.82886
GALNT14 polypeptide N-acetylgalactosaminyltransferase 14 3.82775
IKZF4 IKAROS family zinc finger 4 (Eos) 3.82673
CLIP3 CAP-GLY domain containing linker protein 3 3.82653
DSCR4 Down syndrome critical region 4 3.82055
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2 3.81899
MYL7 myosin, light chain 7, regulatory 3.81849
TMEM151B transmembrane protein 151B 3.81366
PIGR polymeric immunoglobulin receptor 3.81324
NRXN2 neurexin 2 3.80633
CCDC40 coiled-coil domain containing 40 3.80613
CRYBB2 crystallin, beta B2 3.78787
FCN1 ficolin (collagen/fibrinogen domain containing) 1 3.78155
ADAMTSL2 ADAMTS-like 2 3.77856
PSMD9 proteasome (prosome, macropain) 26S subunit, non-ATPase, 9 3.77632
CASP10 caspase 10, apoptosis-related cysteine peptidase 3.77357
HTR5A 5-hydroxytryptamine (serotonin) receptor 5A, G protein-coupled 3.76561
POU5F1B POU class 5 homeobox 1B 3.7649
PABPC3 poly(A) binding protein, cytoplasmic 3 3.7642
DFFB DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase) 3.76075
ABHD2 abhydrolase domain containing 2 3.7487
DAZL deleted in azoospermia-like 3.74628
CCL15 chemokine (C-C motif) ligand 15 3.73827
SLC2A9 solute carrier family 2 (facilitated glucose transporter), member 9 3.73183
PSKH1 protein serine kinase H1 3.73168
ADD2 adducin 2 (beta) 3.72549
SIX5 SIX homeobox 5 3.7171
ABLIM1 actin binding LIM protein 1 3.71285
CHRNE cholinergic receptor, nicotinic, epsilon (muscle) 3.70665
COQ6 coenzyme Q6 monooxygenase 3.70378
CDH22 cadherin 22, type 2 3.69993
BAG4 BCL2-associated athanogene 4 3.69323
KCNH4 potassium channel, voltage gated eag related subfamily H, member 4 3.68808
PRPSAP2 phosphoribosyl pyrophosphate synthetase-associated protein 2 3.67706
DNAAF8 dynein axonemal assembly factor 8 3.67294
KIAA1614 KIAA1614 3.67148
PRR7 proline rich 7 (synaptic) 3.67145
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1 3.6642
TSPAN12 tetraspanin 12 3.66064
DOCK3 dedicator of cytokinesis 3 3.65887
OSM oncostatin M 3.65849
TENM1 teneurin transmembrane protein 1 3.65834
TACR3 tachykinin receptor 3 3.65693
AUNIP aurora kinase A and ninein interacting protein 3.6417
IL12RB1 interleukin 12 receptor, beta 1 3.6357
B3GNT4 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4 3.63508
FOS FBJ murine osteosarcoma viral oncogene homolog 3.63095
KLHL1 kelch-like family member 1 3.62964
RAB35 RAB35, member RAS oncogene family 3.62741
DMBT1 deleted in malignant brain tumors 1 3.62225
MRPL44 mitochondrial ribosomal protein L44 3.62133
MACROH2A2 macroH2A.2 histone 3.61493
RBM17 RNA binding motif protein 17 3.61468
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 3.6133
PAK6 p21 protein (Cdc42/Rac)-activated kinase 6 3.61129
MORN1 MORN repeat containing 1 3.60974
TRAT1 T cell receptor associated transmembrane adaptor 1 3.60872
MYOC myocilin, trabecular meshwork inducible glucocorticoid response 3.6037
VRTN vertebrae development associated 3.60363
KCNA10 potassium channel, voltage gated shaker related subfamily A, member 10 3.59292
MFF mitochondrial fission factor 3.58769
MYH10 myosin, heavy chain 10, non-muscle 3.58422
ZNF571 zinc finger protein 571 3.58188
ERBB4 erb-b2 receptor tyrosine kinase 4 3.57068
RABGAP1L RAB GTPase activating protein 1-like 3.56468
DENR density-regulated protein 3.56174
GADD45G growth arrest and DNA-damage-inducible, gamma 3.5573
ZSCAN9 zinc finger and SCAN domain containing 9 3.54221
CDK18 cyclin-dependent kinase 18 3.54204
CRTAC1 cartilage acidic protein 1 3.54067
RPS4X ribosomal protein S4, X-linked 3.53933
DONSON downstream neighbor of SON 3.53613
PDK1 pyruvate dehydrogenase kinase, isozyme 1 3.53562
REEP2 receptor accessory protein 2 3.53338
SNW1 SNW domain containing 1 3.52702
KHK ketohexokinase (fructokinase) 3.51877
CD9 CD9 molecule 3.51483
CACNG5 calcium channel, voltage-dependent, gamma subunit 5 3.51479
CCT5 chaperonin containing TCP1, subunit 5 (epsilon) 3.51136
SOX2 SRY (sex determining region Y)-box 2 3.51023
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B 3.50811
AGER advanced glycosylation end product-specific receptor 3.5017
IL27RA interleukin 27 receptor, alpha 3.49806
CCDC25 coiled-coil domain containing 25 3.49685
CTIF CBP80/20-dependent translation initiation factor 3.49106
FBXW2 F-box and WD repeat domain containing 2 3.48708
SFXN3 sideroflexin 3 3.48604
CHRND cholinergic receptor, nicotinic, delta (muscle) 3.46454
TUBA8 tubulin, alpha 8 3.46397
QPCT glutaminyl-peptide cyclotransferase 3.46113
GLYAT glycine-N-acyltransferase 3.46074
MYL3 myosin, light chain 3, alkali; ventricular, skeletal, slow 3.45879
PGM3 phosphoglucomutase 3 3.45813
SLC22A2 solute carrier family 22 (organic cation transporter), member 2 3.45546
IL24 interleukin 24 3.44799
GATA3 GATA binding protein 3 3.44516
ZNF529 zinc finger protein 529 3.43833
MAP1LC3C microtubule-associated protein 1 light chain 3 gamma 3.4374
TMEM132A transmembrane protein 132A 3.42189
MAP3K4 mitogen-activated protein kinase kinase kinase 4 3.41493
GPD1 glycerol-3-phosphate dehydrogenase 1 (soluble) 3.4117
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5 3.40976
TMEM140 transmembrane protein 140 3.40973
MTMR10 myotubularin related protein 10 3.40805
SEMA6B sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B 3.40748
EOGT EGF domain-specific O-linked N-acetylglucosamine (GlcNAc) transferase 3.40672
ACTR8 ARP8 actin-related protein 8 homolog (yeast) 3.40588
MPDZ multiple PDZ domain protein 3.40314
CUBN cubilin (intrinsic factor-cobalamin receptor) 3.39784
SYNE2 spectrin repeat containing, nuclear envelope 2 3.39768
S100A5 S100 calcium binding protein A5 3.3953
ERMP1 endoplasmic reticulum metallopeptidase 1 3.3913
ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain 3.39122
MAP4 microtubule-associated protein 4 3.39001
SPINK2 serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) 3.38899
KYNU kynureninase 3.38494
MGAT1 mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase 3.38327
BCAN brevican 3.38264
ZNF506 zinc finger protein 506 3.37995
CDC42SE1 CDC42 small effector 1 3.37918
CCL24 chemokine (C-C motif) ligand 24 3.37906
NKX2-8 NK2 homeobox 8 3.37585
IGF2BP1 insulin-like growth factor 2 mRNA binding protein 1 3.37554
MYT1 myelin transcription factor 1 3.3754
HBQ1 hemoglobin, theta 1 3.37271
SLC47A1 solute carrier family 47 (multidrug and toxin extrusion), member 1 3.37183
MICB MHC class I polypeptide-related sequence B 3.37145
NAT8B N-acetyltransferase 8B (GCN5-related, putative, gene/pseudogene) 3.36993
SH3BP2 SH3-domain binding protein 2 3.36603
CXCR4 chemokine (C-X-C motif) receptor 4 3.36446
OSBPL3 oxysterol binding protein-like 3 3.36186
TMEM156 transmembrane protein 156 3.35985
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 3.35863
SERINC3 serine incorporator 3 3.35735
ROBO4 roundabout, axon guidance receptor, homolog 4 (Drosophila) 3.35238
RNPEPL1 arginyl aminopeptidase (aminopeptidase B)-like 1 3.34262
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast) 3.3403
ALG3 ALG3, alpha-1,3- mannosyltransferase 3.33014
BCL7B B-cell CLL/lymphoma 7B 3.33
APOBEC3F apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3F 3.32733
C1RL complement component 1, r subcomponent-like 3.31871
RPL37 ribosomal protein L37 3.31869
UPK3A uroplakin 3A 3.31859
MCC mutated in colorectal cancers 3.31627
BCAS1 breast carcinoma amplified sequence 1 3.30908
STX18 syntaxin 18 3.30642
TRIP13 thyroid hormone receptor interactor 13 3.30485
EIF3F eukaryotic translation initiation factor 3, subunit F 3.30036
HTATIP2 HIV-1 Tat interactive protein 2, 30kDa 3.2973
GSTT1 glutathione S-transferase theta 1 3.29643
NCALD neurocalcin delta 3.29002
HCP5 HLA complex P5 (non-protein coding) 3.28939
SLC24A2 solute carrier family 24 (sodium/potassium/calcium exchanger), member 2 3.28746
RPS14 ribosomal protein S14 3.28024
FGR FGR proto-oncogene, Src family tyrosine kinase 3.27823
NLGN3 neuroligin 3 3.27495
NAGA N-acetylgalactosaminidase, alpha- 3.2737
HS3ST1 heparan sulfate (glucosamine) 3-O-sulfotransferase 1 3.27336
CPNE7 copine VII 3.26898
TSPYL1 TSPY-like 1 3.26614
KCNJ15 potassium channel, inwardly rectifying subfamily J, member 15 3.26342
MPHOSPH9 M-phase phosphoprotein 9 3.26288
SNAPC1 small nuclear RNA activating complex, polypeptide 1, 43kDa 3.26028
RPL27A ribosomal protein L27a 3.25631
TDRD12 tudor domain containing 12 3.25538
CTSS cathepsin S 3.25014
PLCB2 phospholipase C, beta 2 3.24905
PPIEL peptidylprolyl isomerase E-like pseudogene 3.24387
BCL6 B-cell CLL/lymphoma 6 3.24339
NALF2 NALCN channel auxiliary factor 2 3.23192
PPIL2 peptidylprolyl isomerase (cyclophilin)-like 2 3.23093
IFT54 intraflagellar transport 54 3.22511
NPPB natriuretic peptide B 3.22109
KRTAP5-9 keratin associated protein 5-9 3.22092
APC2 adenomatosis polyposis coli 2 3.21603
CDH15 cadherin 15, type 1, M-cadherin (myotubule) 3.21564
SPAG6 sperm associated antigen 6 3.21056
GEMIN7 gem (nuclear organelle) associated protein 7 3.20275
RPL24 ribosomal protein L24 3.20218
NR1H4 nuclear receptor subfamily 1, group H, member 4 3.20185
EHHADH enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase 3.19381
TRMT44 tRNA methyltransferase 44 homolog (S. cerevisiae) 3.19029
ZNF184 zinc finger protein 184 3.18681
MAN2B2 mannosidase, alpha, class 2B, member 2 3.18566
TREM1 triggering receptor expressed on myeloid cells 1 3.18414
IRF6 interferon regulatory factor 6 3.18046
DISC1 disrupted in schizophrenia 1 3.17874
KRI1 KRI1 homolog (S. cerevisiae) 3.17824
DESI1 desumoylating isopeptidase 1 3.17814
DLL3 delta-like 3 (Drosophila) 3.17737
COL4A4 collagen, type IV, alpha 4 3.17166
MAGEA8 melanoma antigen family A8 3.17079
GNG4 guanine nucleotide binding protein (G protein), gamma 4 3.17019
CYP2W1 cytochrome P450, family 2, subfamily W, polypeptide 1 3.16836
KCNG2 potassium channel, voltage gated modifier subfamily G, member 2 3.16643
TBCE tubulin folding cofactor E 3.16093
SDHAF1 succinate dehydrogenase complex assembly factor 1 3.16092
KRT3 keratin 3, type II 3.15666
HAO2 hydroxyacid oxidase 2 (long chain) 3.15382
SLC34A2 solute carrier family 34 (type II sodium/phosphate cotransporter), member 2 3.15248
EAF2 ELL associated factor 2 3.14458
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9 3.14143
FIBP fibroblast growth factor (acidic) intracellular binding protein 3.14045
CSDC2 cold shock domain containing C2, RNA binding 3.13105
CYP4F2 cytochrome P450, family 4, subfamily F, polypeptide 2 3.12977
EIF2B1 eukaryotic translation initiation factor 2B, subunit 1 alpha, 26kDa 3.12969
ST3GAL1 ST3 beta-galactoside alpha-2,3-sialyltransferase 1 3.12951
ICA1 islet cell autoantigen 1, 69kDa 3.12522
BHMT betaine--homocysteine S-methyltransferase 3.12224
GDF5 growth differentiation factor 5 3.12042
ALPI alkaline phosphatase, intestinal 3.12004
HTR1F 5-hydroxytryptamine (serotonin) receptor 1F, G protein-coupled 3.1197
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1 3.11746
GGTLC1 gamma-glutamyltransferase light chain 1 3.11144
C5ORF22 chromosome 5 open reading frame 22 3.11079
DNASE2B deoxyribonuclease II beta 3.10972
LINC02249 long intergenic non-protein coding RNA 2249 3.10399
ZNF440 zinc finger protein 440 3.10348
NONO non-POU domain containing, octamer-binding 3.10197
TBC1D29P TBC1 domain family member 29, pseudogene 3.10164
COTL1 coactosin-like F-actin binding protein 1 3.09846
PRKAA2 protein kinase, AMP-activated, alpha 2 catalytic subunit 3.09724
POU5F1P3 POU class 5 homeobox 1 pseudogene 3 3.09599
TMEM177 transmembrane protein 177 3.09501
ANKZF1 ankyrin repeat and zinc finger domain containing 1 3.09027
HPD 4-hydroxyphenylpyruvate dioxygenase 3.09021
APOM apolipoprotein M 3.08966
HLA-F-AS1 HLA-F antisense RNA 1 3.08437
MYRIP myosin VIIA and Rab interacting protein 3.08368
CAMK2B calcium/calmodulin-dependent protein kinase II beta 3.08319
ASB13 ankyrin repeat and SOCS box containing 13 3.0807
PRLH prolactin releasing hormone 3.06906
EPO erythropoietin 3.06314
TCP1 t-complex 1 3.06209
B3GAT1 beta-1,3-glucuronyltransferase 1 3.0599
SLC22A8 solute carrier family 22 (organic anion transporter), member 8 3.05734
BCS1L BC1 (ubiquinol-cytochrome c reductase) synthesis-like 3.052
CPEB1 cytoplasmic polyadenylation element binding protein 1 3.04406
UBE2G1 ubiquitin-conjugating enzyme E2G 1 3.04142
DTX4 deltex 4, E3 ubiquitin ligase 3.04
RPS13 ribosomal protein S13 3.03916
EPOR erythropoietin receptor 3.03188
C9 complement component 9 3.03114
KCNC4 potassium channel, voltage gated Shaw related subfamily C, member 4 3.03096
UNC119B unc-119 homolog B (C. elegans) 3.02969
GPR176 G protein-coupled receptor 176 3.02946
RHOB ras homolog family member B 3.02737
POLR3F polymerase (RNA) III (DNA directed) polypeptide F, 39 kDa 3.02189
PPM1B protein phosphatase, Mg2+/Mn2+ dependent, 1B 3.02142
FNDC4 fibronectin type III domain containing 4 3.01808
APAF1 apoptotic peptidase activating factor 1 3.01437
SLC14A1 solute carrier family 14 (urea transporter), member 1 (Kidd blood group) 3.01219
S1PR2 sphingosine-1-phosphate receptor 2 3.01007
KCNAB3 potassium channel, voltage gated subfamily A regulatory beta subunit 3 3.0087
ENTPD2 ectonucleoside triphosphate diphosphohydrolase 2 3.00861
KIF25 kinesin family member 25 3.00525
NQO2 NAD(P)H dehydrogenase, quinone 2 3.00329
GLDC glycine dehydrogenase (decarboxylating) 3.00183

decreased expression

Symbol Name Standardized Value
BCL2 B-cell CLL/lymphoma 2 -7.68636
C2CD5 C2 calcium-dependent domain containing 5 -6.68807
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 -6.55142
CAND1 cullin-associated and neddylation-dissociated 1 -5.94054
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) -5.79721
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta -5.47826
PRDM5 PR domain containing 5 -5.43873
PNLIPRP1 pancreatic lipase-related protein 1 -5.36003
CLCN7 chloride channel, voltage-sensitive 7 -5.32962
DSG1 desmoglein 1 -5.2202
MYLK myosin light chain kinase -5.18056
TBL1X transducin (beta)-like 1X-linked -5.17864
NPRL2 nitrogen permease regulator-like 2 (S. cerevisiae) -5.173
KITLG KIT ligand -5.05093
EGF epidermal growth factor -5.05032
USP12P1 ubiquitin specific peptidase 12 pseudogene 1 -4.99258
CLDN14 claudin 14 -4.9792
LINC00474 long intergenic non-protein coding RNA 474 -4.95152
DUSP3 dual specificity phosphatase 3 -4.9397
INPP5A inositol polyphosphate-5-phosphatase, 40kDa -4.8769
IL13RA1 interleukin 13 receptor, alpha 1 -4.85183
ZNF580 zinc finger protein 580 -4.84899
RPS4Y1 ribosomal protein S4, Y-linked 1 -4.84822
SELENBP1 selenium binding protein 1 -4.81381
KCNJ8 potassium channel, inwardly rectifying subfamily J, member 8 -4.80911
GP6 glycoprotein VI (platelet) -4.80474
ASXL1 additional sex combs like transcriptional regulator 1 -4.7442
CDK6 cyclin-dependent kinase 6 -4.68468
WAC WW domain containing adaptor with coiled-coil -4.68412
PROSER1 proline and serine rich 1 -4.66588
PTGER3 prostaglandin E receptor 3 (subtype EP3) -4.66514
C3ORF52 chromosome 3 open reading frame 52 -4.64261
KLHL21 kelch-like family member 21 -4.64246
NDUFB4 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 4, 15kDa -4.6171
ABCC9 ATP-binding cassette, sub-family C (CFTR/MRP), member 9 -4.57771
SMTN smoothelin -4.57271
GABRA2 gamma-aminobutyric acid (GABA) A receptor, alpha 2 -4.56878
MTNR1A melatonin receptor 1A -4.55108
EOLA2-DT EOLA2 divergent transcript -4.54767
FRS2 fibroblast growth factor receptor substrate 2 -4.52909
ANXA9 annexin A9 -4.50816
ARID1A AT rich interactive domain 1A (SWI-like) -4.50403
CPA1 carboxypeptidase A1 (pancreatic) -4.48519
IDE insulin-degrading enzyme -4.42543
CHRNB3 cholinergic receptor, nicotinic, beta 3 (neuronal) -4.39773
PENK proenkephalin -4.37241
GAN gigaxonin -4.36978
TRPM1 transient receptor potential cation channel, subfamily M, member 1 -4.34898
NME3 NME/NM23 nucleoside diphosphate kinase 3 -4.34001
MEIS2 Meis homeobox 2 -4.33017
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) -4.32628
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced -4.31503
AMFR autocrine motility factor receptor, E3 ubiquitin protein ligase -4.27916
AKAP17A A kinase (PRKA) anchor protein 17A -4.26344
TGFBR1 transforming growth factor, beta receptor 1 -4.25021
GABPB1 GA binding protein transcription factor, beta subunit 1 -4.25006
TMEM87A transmembrane protein 87A -4.24949
BMPR1A bone morphogenetic protein receptor, type IA -4.24268
HINT1 histidine triad nucleotide binding protein 1 -4.24182
SMURF1 SMAD specific E3 ubiquitin protein ligase 1 -4.23285
WDR6 WD repeat domain 6 -4.2318
PLCXD1 phosphatidylinositol-specific phospholipase C, X domain containing 1 -4.23107
IGFBP2 insulin-like growth factor binding protein 2, 36kDa -4.21066
BTRC beta-transducin repeat containing E3 ubiquitin protein ligase -4.2101
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic -4.20455
LATS1 large tumor suppressor kinase 1 -4.18966
CFD complement factor D (adipsin) -4.1722
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) -4.16104
NLGN4Y neuroligin 4, Y-linked -4.15947
DSC1 desmocollin 1 -4.14834
SLC66A2 solute carrier family 66 member 2 -4.14659
GFRA1 GDNF family receptor alpha 1 -4.14291
IFNB1 interferon, beta 1, fibroblast -4.1376
MACF1 microtubule-actin crosslinking factor 1 -4.13497
XPO6 exportin 6 -4.12722
MTMR4 myotubularin related protein 4 -4.11547
SLC35C2 solute carrier family 35 (GDP-fucose transporter), member C2 -4.09763
MED13 mediator complex subunit 13 -4.0932
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha -4.07978
PRKCA protein kinase C, alpha -4.0764
RPL10 ribosomal protein L10 -4.07412
SYTL2 synaptotagmin-like 2 -4.07181
APOLD1 apolipoprotein L domain containing 1 -4.03835
UBE2I ubiquitin-conjugating enzyme E2I -4.03833
PPP4R4 protein phosphatase 4, regulatory subunit 4 -4.03691
DOCK1 dedicator of cytokinesis 1 -4.01455
NR5A2 nuclear receptor subfamily 5, group A, member 2 -4.00794
FMOD fibromodulin -4.00525
RASA1 RAS p21 protein activator (GTPase activating protein) 1 -3.96822
RAB11FIP2 RAB11 family interacting protein 2 (class I) -3.96196
PPP2R2D protein phosphatase 2, regulatory subunit B, delta -3.95006
PNLIPRP2 pancreatic lipase-related protein 2 -3.93423
IDS iduronate 2-sulfatase -3.93363
KHNYN KH and NYN domain containing -3.92246
IFNA14 interferon, alpha 14 -3.91715
UTY ubiquitously transcribed tetratricopeptide repeat containing, Y-linked -3.88428
NAGPA N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase -3.88281
SMARCA1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1 -3.87093
OLAH oleoyl-ACP hydrolase -3.86582
HSPD1 heat shock 60kDa protein 1 (chaperonin) -3.85642
AGO2 argonaute RISC catalytic component 2 -3.84921
LALBA lactalbumin, alpha- -3.82402
SLC6A16 solute carrier family 6, member 16 -3.81405
ARHGAP12 Rho GTPase activating protein 12 -3.80386
CCR7 chemokine (C-C motif) receptor 7 -3.79288
ETNK1 ethanolamine kinase 1 -3.78832
CD99 CD99 molecule -3.7871
GPR85 G protein-coupled receptor 85 -3.77167
TNFAIP8 tumor necrosis factor, alpha-induced protein 8 -3.76864
RAP2C RAP2C, member of RAS oncogene family -3.76675
GLI2 GLI family zinc finger 2 -3.7636
UBA6 ubiquitin-like modifier activating enzyme 6 -3.76356
ATN1 atrophin 1 -3.76157
CREBBP CREB binding protein -3.74425
USP36 ubiquitin specific peptidase 36 -3.73778
FAM162A family with sequence similarity 162, member A -3.7138
C1ORF68 chromosome 1 open reading frame 68 -3.7125
CARD14 caspase recruitment domain family, member 14 -3.70925
WBP1L WW domain binding protein 1-like -3.70902
CTRB2 chymotrypsinogen B2 -3.69781
PTGDR prostaglandin D2 receptor (DP) -3.69773
PNLIP pancreatic lipase -3.69413
RASAL2 RAS protein activator like 2 -3.6745
COX17 COX17 cytochrome c oxidase copper chaperone -3.67184
SLC16A7 solute carrier family 16 (monocarboxylate transporter), member 7 -3.66653
MSRB1 methionine sulfoxide reductase B1 -3.66482
RXYLT1 ribitol xylosyltransferase 1 -3.65949
PANX1 pannexin 1 -3.65258
EOLA1 endothelium and lymphocyte associated ASCH domain 1 -3.65045
DPM3 dolichyl-phosphate mannosyltransferase polypeptide 3 -3.63815
PLSCR2 phospholipid scramblase 2 -3.63686
IPPK inositol 1,3,4,5,6-pentakisphosphate 2-kinase -3.60771
WWP1 WW domain containing E3 ubiquitin protein ligase 1 -3.58819
SEPHS1 selenophosphate synthetase 1 -3.58435
CHM choroideremia (Rab escort protein 1) -3.58075
H3-3B H3.3 histone B -3.57804
CERS4 ceramide synthase 4 -3.5774
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box) -3.57655
MRPS15 mitochondrial ribosomal protein S15 -3.56812
PTEN phosphatase and tensin homolog -3.55901
KCNE2 potassium channel, voltage gated subfamily E regulatory beta subunit 2 -3.55177
PLEKHM2 pleckstrin homology domain containing, family M (with RUN domain) member 2 -3.55141
CNOT2 CCR4-NOT transcription complex, subunit 2 -3.55001
ZNF263 zinc finger protein 263 -3.54848
GML glycosylphosphatidylinositol anchored molecule like -3.54184
POPDC2 popeye domain containing 2 -3.53963
CRABP2 cellular retinoic acid binding protein 2 -3.52533
LGALSL lectin, galactoside-binding-like -3.521
PACSIN3 protein kinase C and casein kinase substrate in neurons 3 -3.51567
ARHGAP5 Rho GTPase activating protein 5 -3.51469
GPR6 G protein-coupled receptor 6 -3.50906
ZMPSTE24 zinc metallopeptidase STE24 -3.50183
CLOCK clock circadian regulator -3.49811
PRSS3 protease, serine, 3 -3.49797
KPNA1 karyopherin alpha 1 (importin alpha 5) -3.4919
HAND2-AS1 HAND2 antisense RNA 1 (head to head) -3.49036
HDAC1 histone deacetylase 1 -3.47286
ZNF710 zinc finger protein 710 -3.47203
PEX11A peroxisomal biogenesis factor 11 alpha -3.46304
HAND1 heart and neural crest derivatives expressed 1 -3.46301
MGMT O-6-methylguanine-DNA methyltransferase -3.45108
SHOC2 soc-2 suppressor of clear homolog (C. elegans) -3.44648
PTOV1 prostate tumor overexpressed 1 -3.44645
DNM1 dynamin 1 -3.44272
SCUBE2 signal peptide, CUB domain, EGF-like 2 -3.44236
MORC2 MORC family CW-type zinc finger 2 -3.44071
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase) -3.43637
KIF24 kinesin family member 24 -3.43574
RNH1 ribonuclease/angiogenin inhibitor 1 -3.4286
GRAP2 GRB2-related adaptor protein 2 -3.42754
ARHGEF12 Rho guanine nucleotide exchange factor (GEF) 12 -3.42564
HOXD11 homeobox D11 -3.42498
PLVAP plasmalemma vesicle associated protein -3.42317
CHML choroideremia-like (Rab escort protein 2) -3.42217
NPHP1 nephronophthisis 1 (juvenile) -3.41674
CIAO3 cytosolic iron-sulfur assembly component 3 -3.41424
CYB5R2 cytochrome b5 reductase 2 -3.41146
MKI67 marker of proliferation Ki-67 -3.40258
BLVRB biliverdin reductase B -3.3984
CNOT1 CCR4-NOT transcription complex, subunit 1 -3.38937
AVL9 AVL9 homolog (S. cerevisiase) -3.38902
YME1L1 YME1-like 1 ATPase -3.38731
PRPH2 peripherin 2 (retinal degeneration, slow) -3.37628
CBX5 chromobox homolog 5 -3.37365
FBXO38 F-box protein 38 -3.37222
LMOD1 leiomodin 1 (smooth muscle) -3.36772
PARD3 par-3 family cell polarity regulator -3.36598
UGT2B15 UDP glucuronosyltransferase 2 family, polypeptide B15 -3.35639
MRAP melanocortin 2 receptor accessory protein -3.35248
VPS28 vacuolar protein sorting 28 homolog (S. cerevisiae) -3.3484
CD72 CD72 molecule -3.34738
GALT galactose-1-phosphate uridylyltransferase -3.34685
DAXX death-domain associated protein -3.34057
SLC25A28 solute carrier family 25 (mitochondrial iron transporter), member 28 -3.3361
NOD2 nucleotide-binding oligomerization domain containing 2 -3.33137
TDRD3 tudor domain containing 3 -3.33081
TTC39A tetratricopeptide repeat domain 39A -3.3242
F2RL2 coagulation factor II (thrombin) receptor-like 2 -3.31996
HOXA11 homeobox A11 -3.31937
MAPK8 mitogen-activated protein kinase 8 -3.31833
IMPA2 inositol(myo)-1(or 4)-monophosphatase 2 -3.31675
IFNA21 interferon, alpha 21 -3.31205
KIF5B kinesin family member 5B -3.30899
GALNT3 polypeptide N-acetylgalactosaminyltransferase 3 -3.30836
APOBEC3B apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B -3.30748
DEXI Dexi homolog (mouse) -3.30574
UBFD1 ubiquitin family domain containing 1 -3.30468
DYRK2 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2 -3.30391
SOX11 SRY (sex determining region Y)-box 11 -3.29647
CARM1 coactivator-associated arginine methyltransferase 1 -3.29642
SLC30A1 solute carrier family 30 (zinc transporter), member 1 -3.29049
NFATC2IP nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 interacting protein -3.28511
ECHDC3 enoyl CoA hydratase domain containing 3 -3.28335
SIRT3 sirtuin 3 -3.28219
DIO2 deiodinase, iodothyronine, type II -3.26942
TIAL1 TIA1 cytotoxic granule-associated RNA binding protein-like 1 -3.26851
MSRB2 methionine sulfoxide reductase B2 -3.26792
MLST8 MTOR associated protein, LST8 homolog (S. cerevisiae) -3.26668
HAPLN1 hyaluronan and proteoglycan link protein 1 -3.26511
OR1E1 olfactory receptor, family 1, subfamily E, member 1 -3.2627
PNISR PNN-interacting serine/arginine-rich protein -3.2586
HLA-DRB1 major histocompatibility complex, class II, DR beta 1 -3.25758
ASAP2 ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 -3.24789
TUBGCP4 tubulin, gamma complex associated protein 4 -3.2458
CPNE1 copine I -3.24561
ELOB elongin B -3.24511
METTL16 methyltransferase like 16 -3.23887
WDR45 WD repeat domain 45 -3.23869
LUC7L LUC7-like (S. cerevisiae) -3.23135
STARD13 StAR-related lipid transfer (START) domain containing 13 -3.21805
MRM3 mitochondrial rRNA methyltransferase 3 -3.20625
RHOD ras homolog family member D -3.206
TRRAP transformation/transcription domain-associated protein -3.20012
SERPINI2 serpin peptidase inhibitor, clade I (pancpin), member 2 -3.1951
GUCY2C guanylate cyclase 2C -3.19415
CETN2 centrin, EF-hand protein, 2 -3.18986
ANKRD11 ankyrin repeat domain 11 -3.18149
WAPL WAPL cohesin release factor -3.17948
PRG3 proteoglycan 3 -3.17491
AFF4 AF4/FMR2 family, member 4 -3.17319
IFNA8 interferon, alpha 8 -3.16592
GBF1 golgi brefeldin A resistant guanine nucleotide exchange factor 1 -3.16317
ISL1 ISL LIM homeobox 1 -3.1622
FGF13 fibroblast growth factor 13 -3.16108
RUBCNL rubicon like autophagy enhancer -3.16083
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked -3.16045
SLC12A1 solute carrier family 12 (sodium/potassium/chloride transporter), member 1 -3.15967
HCFC1R1 host cell factor C1 regulator 1 (XPO1 dependent) -3.15839
FLT1 fms-related tyrosine kinase 1 -3.15784
WDFY3 WD repeat and FYVE domain containing 3 -3.15344
TSPAN5 tetraspanin 5 -3.15188
PHLPP2 PH domain and leucine rich repeat protein phosphatase 2 -3.13972
WNT4 wingless-type MMTV integration site family, member 4 -3.13967
SETBP1 SET binding protein 1 -3.13435
RCAN1 regulator of calcineurin 1 -3.13041
AQP8 aquaporin 8 -3.12515
PLAG1 pleiomorphic adenoma gene 1 -3.11783
CLMN calmin (calponin-like, transmembrane) -3.11704
LRPPRC leucine-rich pentatricopeptide repeat containing -3.11207
TRIM32 tripartite motif containing 32 -3.11055
TMEM248 transmembrane protein 248 -3.10752
TRPM4 transient receptor potential cation channel, subfamily M, member 4 -3.10658
PAGE4 P antigen family, member 4 (prostate associated) -3.10638
CALCOCO2 calcium binding and coiled-coil domain 2 -3.10546
GTF3C1 general transcription factor IIIC, polypeptide 1, alpha 220kDa -3.10455
WASF2 WAS protein family, member 2 -3.10239
RPA4 replication protein A4, 30kDa -3.10142
MCMBP minichromosome maintenance complex binding protein -3.10002
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme -3.09656
FCGRT Fc fragment of IgG, receptor, transporter, alpha -3.09565
SMARCC1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 -3.09401
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1 -3.09019
BRAF B-Raf proto-oncogene, serine/threonine kinase -3.08956
FOXK2 forkhead box K2 -3.07832
GSTK1 glutathione S-transferase kappa 1 -3.07767
GCG glucagon -3.07581
ASNS asparagine synthetase (glutamine-hydrolyzing) -3.07142
SHMT2 serine hydroxymethyltransferase 2 (mitochondrial) -3.07066
TFF1 trefoil factor 1 -3.06497
POF1B premature ovarian failure, 1B -3.05954
COL15A1 collagen, type XV, alpha 1 -3.05848
ROCK2 Rho-associated, coiled-coil containing protein kinase 2 -3.05776
USP7 ubiquitin specific peptidase 7 (herpes virus-associated) -3.05755
AMZ2 archaelysin family metallopeptidase 2 -3.05707
GABRE gamma-aminobutyric acid (GABA) A receptor, epsilon -3.05475
AZGP1 alpha-2-glycoprotein 1, zinc-binding -3.05037
LTB4R leukotriene B4 receptor -3.04234
TIAM1 T-cell lymphoma invasion and metastasis 1 -3.04163
BBIP1 BBSome interacting protein 1 -3.04041
RAG1 recombination activating gene 1 -3.03548
PLEKHA1 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1 -3.03511
CYP7B1 cytochrome P450, family 7, subfamily B, polypeptide 1 -3.03498
PRSS1 protease, serine, 1 (trypsin 1) -3.02905
UGT2B17 UDP glucuronosyltransferase 2 family, polypeptide B17 -3.02429
IL37 interleukin 37 -3.02281
SMAD5-AS1 SMAD5 antisense RNA 1 -3.0204
ABCA5 ATP-binding cassette, sub-family A (ABC1), member 5 -3.01748
RAD21L1 RAD21-like 1 (S. pombe) -3.01623
UNC5C unc-5 homolog C (C. elegans) -3.01397
SPINK5 serine peptidase inhibitor, Kazal type 5 -3.01276
JAK1 Janus kinase 1 -3.01211
LIPF lipase, gastric -3.01082
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) -3.00998
EFR3A EFR3 homolog A (S. cerevisiae) -3.0085
STAB1 stabilin 1 -3.00671
MXI1 MAX interactor 1, dimerization protein -3.0027
AEN apoptosis enhancing nuclease -3.00249