solasodine-3749 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the solasodine-3749 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
A4GALT alpha 1,4-galactosyltransferase
ACO2 aconitase 2, mitochondrial
ACRV1 acrosomal vesicle protein 1
ADAMTS13 ADAM metallopeptidase with thrombospondin type 1 motif, 13
AFF1 AF4/FMR2 family, member 1
AFF4 AF4/FMR2 family, member 4
ALOXE3 arachidonate lipoxygenase 3
ALX3 ALX homeobox 3
ANKLE2 ankyrin repeat and LEM domain containing 2
AQP3 aquaporin 3 (Gill blood group)
BBC3 BCL2 binding component 3
BST1 bone marrow stromal cell antigen 1
CCL8 chemokine (C-C motif) ligand 8
CD101 CD101 molecule
CD6 CD6 molecule
CFB complement factor B
CHIA chitinase, acidic
COL1A2 collagen, type I, alpha 2
COL4A3 collagen, type IV, alpha 3 (Goodpasture antigen)
CPN2 carboxypeptidase N, polypeptide 2
CRISP2 cysteine-rich secretory protein 2
CYBA cytochrome b-245, alpha polypeptide
CYLC1 cylicin, basic protein of sperm head cytoskeleton 1
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6
DCN decorin
DEFA4 defensin, alpha 4, corticostatin
DNAAF1 dynein, axonemal, assembly factor 1
DNAJC16 DnaJ (Hsp40) homolog, subfamily C, member 16
DPF1 D4, zinc and double PHD fingers family 1
DPY19L1 dpy-19-like 1 (C. elegans)
DSCAM Down syndrome cell adhesion molecule
EPHB1 EPH receptor B1
EPS8L1 EPS8-like 1
ERC2 ELKS/RAB6-interacting/CAST family member 2
EXOC6B exocyst complex component 6B
EYA4 EYA transcriptional coactivator and phosphatase 4
FRMD4B FERM domain containing 4B
FTCD formimidoyltransferase cyclodeaminase
FZD1 frizzled class receptor 1
GDF5 growth differentiation factor 5
GGT1 gamma-glutamyltransferase 1
GJA9 gap junction protein, alpha 9, 59kDa
GPR135 G protein-coupled receptor 135
HEMK1 HemK methyltransferase family member 1
HRASLS2 HRAS-like suppressor 2
IDS iduronate 2-sulfatase
IL36A interleukin 36, alpha
IRF8 interferon regulatory factor 8
ITGA8 integrin, alpha 8
ITGB4 integrin, beta 4
JAK3 Janus kinase 3
KALRN kalirin, RhoGEF kinase
KANSL3 KAT8 regulatory NSL complex subunit 3
KCND3 potassium channel, voltage gated Shal related subfamily D, member 3
KCNN2 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2
KLF9 Kruppel-like factor 9
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1
MEG3 maternally expressed 3 (non-protein coding)
MFAP2 microfibrillar-associated protein 2
MLANA melan-A
MYL3 myosin, light chain 3, alkali; ventricular, skeletal, slow
NR4A3 nuclear receptor subfamily 4, group A, member 3
NUP188 nucleoporin 188kDa
OR2B6 olfactory receptor, family 2, subfamily B, member 6
PAWR PRKC, apoptosis, WT1, regulator
PBX2 pre-B-cell leukemia homeobox 2
PCDH11X protocadherin 11 X-linked
PCDHGA10 protocadherin gamma subfamily A, 10
PDIA2 protein disulfide isomerase family A, member 2
PRKACA protein kinase, cAMP-dependent, catalytic, alpha
PSG11 pregnancy specific beta-1-glycoprotein 11
PSG4 pregnancy specific beta-1-glycoprotein 4
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
PYY peptide YY
RAB3D RAB3D, member RAS oncogene family
RAB6A RAB6A, member RAS oncogene family
RB1 retinoblastoma 1
RHAG Rh-associated glycoprotein
RPL7 ribosomal protein L7
SAG S-antigen; retina and pineal gland (arrestin)
SDS serine dehydratase
SERPINB13 serpin peptidase inhibitor, clade B (ovalbumin), member 13
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3
SFTPB surfactant protein B
SLC44A1 solute carrier family 44 (choline transporter), member 1
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4
SMO smoothened, frizzled class receptor
SOCS7 suppressor of cytokine signaling 7
SP110 SP110 nuclear body protein
SULT4A1 sulfotransferase family 4A, member 1
TAGLN3 transgelin 3
TCL6 T-cell leukemia/lymphoma 6 (non-protein coding)
TNKS tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase
TNPO2 transportin 2
TRA T cell receptor alpha locus
TRD T cell receptor delta locus
TRIM15 tripartite motif containing 15
TYMP thymidine phosphorylase
USP22 ubiquitin specific peptidase 22

decreased expression

Symbol Name
ABHD17B abhydrolase domain containing 17B
ADAP2 ArfGAP with dual PH domains 2
ALDH3A1 aldehyde dehydrogenase 3 family, member A1
ARMC4 armadillo repeat containing 4
ASIC3 acid sensing (proton gated) ion channel 3
ATAD5 ATPase family, AAA domain containing 5
BAHCC1 BAH domain and coiled-coil containing 1
BDKRB1 bradykinin receptor B1
BEND5 BEN domain containing 5
C17ORF53 chromosome 17 open reading frame 53
C17ORF70 chromosome 17 open reading frame 70
C22ORF29 chromosome 22 open reading frame 29
CAMKMT calmodulin-lysine N-methyltransferase
CARD8 caspase recruitment domain family, member 8
CD70 CD70 molecule
CDH7 cadherin 7, type 2
CDK6 cyclin-dependent kinase 6
CFAP45 cilia and flagella associated protein 45
CORO1A coronin, actin binding protein, 1A
CPZ carboxypeptidase Z
DDIT4 DNA-damage-inducible transcript 4
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding)
DHRS9 dehydrogenase/reductase (SDR family) member 9
DNAH7 dynein, axonemal, heavy chain 7
DPF3 D4, zinc and double PHD fingers, family 3
ELSPBP1 epididymal sperm binding protein 1
ERMP1 endoplasmic reticulum metallopeptidase 1
ETNK2 ethanolamine kinase 2
ETV6 ets variant 6
FBRS fibrosin
FBXL7 F-box and leucine-rich repeat protein 7
FBXO2 F-box protein 2
FGF23 fibroblast growth factor 23
GABBR1 gamma-aminobutyric acid (GABA) B receptor, 1
GAS8 growth arrest-specific 8
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GNG7 guanine nucleotide binding protein (G protein), gamma 7
GSDMD gasdermin D
GTF2A1 general transcription factor IIA, 1, 19/37kDa
HAUS2 HAUS augmin-like complex, subunit 2
HERC3 HECT and RLD domain containing E3 ubiquitin protein ligase 3
HIST1H1D histone cluster 1, H1d
HIST1H4C histone cluster 1, H4c
IFIT2 interferon-induced protein with tetratricopeptide repeats 2
IL11RA interleukin 11 receptor, alpha
IRF2BP1 interferon regulatory factor 2 binding protein 1
ITPKA inositol-trisphosphate 3-kinase A
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2
KDM8 lysine (K)-specific demethylase 8
KIAA1107 KIAA1107
KRT8P12 keratin 8 pseudogene 12
LIN7B lin-7 homolog B (C. elegans)
LMCD1 LIM and cysteine-rich domains 1
LRFN4 leucine rich repeat and fibronectin type III domain containing 4
LRRC37A3 leucine rich repeat containing 37, member A3
LZTR1 leucine-zipper-like transcription regulator 1
ME3 malic enzyme 3, NADP(+)-dependent, mitochondrial
METTL16 methyltransferase like 16
MGC12488
MMP2 matrix metallopeptidase 2
MMP3 matrix metallopeptidase 3
MNX1 motor neuron and pancreas homeobox 1
NPFFR1 neuropeptide FF receptor 1
NPY1R neuropeptide Y receptor Y1
ODF2 outer dense fiber of sperm tails 2
OR7E156P olfactory receptor, family 7, subfamily E, member 156 pseudogene
PLA2G15 phospholipase A2, group XV
PRSS8 protease, serine, 8
R3HCC1L R3H domain and coiled-coil containing 1-like
RAB11FIP1 RAB11 family interacting protein 1 (class I)
RHOBTB2 Rho-related BTB domain containing 2
RNF125 ring finger protein 125, E3 ubiquitin protein ligase
RPGRIP1L RPGRIP1-like
S100A3 S100 calcium binding protein A3
SAYSD1 SAYSVFN motif domain containing 1
SCG2 secretogranin II
SCN8A sodium channel, voltage gated, type VIII alpha subunit
SELL selectin L
SLC29A3 solute carrier family 29 (equilibrative nucleoside transporter), member 3
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1
SLC46A3 solute carrier family 46, member 3
SLITRK5 SLIT and NTRK-like family, member 5
SMARCD3 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
SMG1 SMG1 phosphatidylinositol 3-kinase-related kinase
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
TAOK1 TAO kinase 1
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TEP1 telomerase-associated protein 1
TNS2 tensin 2
TPCN1 two pore segment channel 1
TRAIP TRAF interacting protein
TSPAN2 tetraspanin 2
UBQLN4 ubiquilin 4
VEZT vezatin, adherens junctions transmembrane protein
VLDLR very low density lipoprotein receptor
ZNF268 zinc finger protein 268
ZNF573 zinc finger protein 573
ZNF639 zinc finger protein 639
ZNF721 zinc finger protein 721
ZNF8 zinc finger protein 8