solasodine-3830 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the solasodine-3830 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
A4GALT alpha 1,4-galactosyltransferase
ACVR1B activin A receptor, type IB
ADAMTS7 ADAM metallopeptidase with thrombospondin type 1 motif, 7
AIPL1 aryl hydrocarbon receptor interacting protein-like 1
AKT2 v-akt murine thymoma viral oncogene homolog 2
ASAP3 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
ASPH aspartate beta-hydroxylase
B9D1 B9 protein domain 1
BCL2L10 BCL2-like 10 (apoptosis facilitator)
BCL6 B-cell CLL/lymphoma 6
C1QL1 complement component 1, q subcomponent-like 1
CACNB2 calcium channel, voltage-dependent, beta 2 subunit
CAMSAP1 calmodulin regulated spectrin-associated protein 1
CASP1 caspase 1, apoptosis-related cysteine peptidase
CASP2 caspase 2, apoptosis-related cysteine peptidase
CBX2 chromobox homolog 2
CCDC64 coiled-coil domain containing 64
CD34 CD34 molecule
CEACAM3 carcinoembryonic antigen-related cell adhesion molecule 3
CILP cartilage intermediate layer protein, nucleotide pyrophosphohydrolase
COL6A1 collagen, type VI, alpha 1
CPEB3 cytoplasmic polyadenylation element binding protein 3
CPN1 carboxypeptidase N, polypeptide 1
CPNE7 copine VII
CTNS cystinosin, lysosomal cystine transporter
CUZD1 CUB and zona pellucida-like domains 1
DAPK3 death-associated protein kinase 3
DCN decorin
DHX34 DEAH (Asp-Glu-Ala-His) box polypeptide 34
DOCK6 dedicator of cytokinesis 6
EMC3 ER membrane protein complex subunit 3
EPB41 erythrocyte membrane protein band 4.1
ERCC2 excision repair cross-complementation group 2
FADS2 fatty acid desaturase 2
FGF2 fibroblast growth factor 2 (basic)
FN1 fibronectin 1
GOLGA8A golgin A8 family, member A
GPLD1 glycosylphosphatidylinositol specific phospholipase D1
GPR135 G protein-coupled receptor 135
GPR176 G protein-coupled receptor 176
HCN4 hyperpolarization activated cyclic nucleotide gated potassium channel 4
HERC4 HECT and RLD domain containing E3 ubiquitin protein ligase 4
HFE hemochromatosis
IGHG1 immunoglobulin heavy constant gamma 1 (G1m marker)
IGLL3P immunoglobulin lambda-like polypeptide 3, pseudogene
INPP4A inositol polyphosphate-4-phosphatase, type I, 107kDa
IRF4 interferon regulatory factor 4
JADE2 jade family PHD finger 2
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1
KLF13 Kruppel-like factor 13
KLHL22 kelch-like family member 22
KMT2A lysine (K)-specific methyltransferase 2A
LAMP1 lysosomal-associated membrane protein 1
LATS1 large tumor suppressor kinase 1
LDB3 LIM domain binding 3
LSS lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)
MAPK14 mitogen-activated protein kinase 14
MAPRE3 microtubule-associated protein, RP/EB family, member 3
MCAM melanoma cell adhesion molecule
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MFN2 mitofusin 2
NDN necdin, melanoma antigen (MAGE) family member
NEURL1 neuralized E3 ubiquitin protein ligase 1
NPR1 natriuretic peptide receptor 1
OSGIN2 oxidative stress induced growth inhibitor family member 2
PAIP2B poly(A) binding protein interacting protein 2B
POM121 POM121 transmembrane nucleoporin
PON1 paraoxonase 1
PQLC2 PQ loop repeat containing 2
PSG3 pregnancy specific beta-1-glycoprotein 3
PSMB9 proteasome (prosome, macropain) subunit, beta type, 9
PTAFR platelet-activating factor receptor
RASAL2 RAS protein activator like 2
RCAN3 RCAN family member 3
RPLP2 ribosomal protein, large, P2
RUNX1 runt-related transcription factor 1
RXRB retinoid X receptor, beta
SELL selectin L
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SH2D1A SH2 domain containing 1A
SLC12A3 solute carrier family 12 (sodium/chloride transporter), member 3
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
SLC9A7 solute carrier family 9, subfamily A (NHE7, cation proton antiporter 7), member 7
SNCG synuclein, gamma (breast cancer-specific protein 1)
SORBS2 sorbin and SH3 domain containing 2
SP1 Sp1 transcription factor
SPTLC2 serine palmitoyltransferase, long chain base subunit 2
ST8SIA4 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4
T T, brachyury homolog (mouse)
TCF3 transcription factor 3
TIMP3 TIMP metallopeptidase inhibitor 3
TM4SF4 transmembrane 4 L six family member 4
TNIK TRAF2 and NCK interacting kinase
TSC22D3 TSC22 domain family, member 3
UBE3A ubiquitin protein ligase E3A
VEGFA vascular endothelial growth factor A
VPS13D vacuolar protein sorting 13 homolog D (S. cerevisiae)
XDH xanthine dehydrogenase
ZBTB20 zinc finger and BTB domain containing 20

decreased expression

Symbol Name
ACADSB acyl-CoA dehydrogenase, short/branched chain
ACTR8 ARP8 actin-related protein 8 homolog (yeast)
AMPD1 adenosine monophosphate deaminase 1
ANKH ANKH inorganic pyrophosphate transport regulator
ANKRD36 ankyrin repeat domain 36
ARHGDIG Rho GDP dissociation inhibitor (GDI) gamma
ARHGEF26 Rho guanine nucleotide exchange factor (GEF) 26
ASIC3 acid sensing (proton gated) ion channel 3
B3GNT4 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4
B4GALT2 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2
BIRC7 baculoviral IAP repeat containing 7
C10ORF95 chromosome 10 open reading frame 95
C11ORF80 chromosome 11 open reading frame 80
C1QTNF9B-AS1 C1QTNF9B antisense RNA 1
C2ORF54 chromosome 2 open reading frame 54
C4BPA complement component 4 binding protein, alpha
C8ORF44 chromosome 8 open reading frame 44
CAMK1 calcium/calmodulin-dependent protein kinase I
CENPC centromere protein C
CFAP44 cilia and flagella associated protein 44
CHST8 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8
CLN6 ceroid-lipofuscinosis, neuronal 6, late infantile, variant
CNR2 cannabinoid receptor 2 (macrophage)
COQ3 coenzyme Q3 methyltransferase
CORO7 coronin 7
CTDP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CUL9 cullin 9
DET1 de-etiolated homolog 1 (Arabidopsis)
DHRS3 dehydrogenase/reductase (SDR family) member 3
EFNA3 ephrin-A3
EGFL7 EGF-like-domain, multiple 7
EMID1 EMI domain containing 1
EXD3 exonuclease 3'-5' domain containing 3
F2R coagulation factor II (thrombin) receptor
F3 coagulation factor III (thromboplastin, tissue factor)
FBXL8 F-box and leucine-rich repeat protein 8
FGD1 FYVE, RhoGEF and PH domain containing 1
FGL1 fibrinogen-like 1
FLCN folliculin
FLJ22184
GAMT guanidinoacetate N-methyltransferase
GK3P glycerol kinase 3 pseudogene
GPR143 G protein-coupled receptor 143
GPT glutamic-pyruvate transaminase (alanine aminotransferase)
HIST1H1B histone cluster 1, H1b
HIST1H4C histone cluster 1, H4c
HOXB2 homeobox B2
IFNA14 interferon, alpha 14
IL22 interleukin 22
KANSL1L KAT8 regulatory NSL complex subunit 1-like
KDM5C lysine (K)-specific demethylase 5C
KIAA0319L KIAA0319-like
LAMP3 lysosomal-associated membrane protein 3
LHX1 LIM homeobox 1
LIME1 Lck interacting transmembrane adaptor 1
LMNB1 lamin B1
LZTS3 leucine zipper, putative tumor suppressor family member 3
MALL mal, T-cell differentiation protein-like
MEFV Mediterranean fever
MNX1 motor neuron and pancreas homeobox 1
MTA2 metastasis associated 1 family, member 2
MYO1F myosin IF
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NUDT18 nudix (nucleoside diphosphate linked moiety X)-type motif 18
PACS1 phosphofurin acidic cluster sorting protein 1
PIGN phosphatidylinositol glycan anchor biosynthesis, class N
PIGZ phosphatidylinositol glycan anchor biosynthesis, class Z
POLL polymerase (DNA directed), lambda
PRR4 proline rich 4 (lacrimal)
RAB3A RAB3A, member RAS oncogene family
RALGPS2 Ral GEF with PH domain and SH3 binding motif 2
RNF125 ring finger protein 125, E3 ubiquitin protein ligase
RPL13P5 ribosomal protein L13 pseudogene 5
RRNAD1 ribosomal RNA adenine dimethylase domain containing 1
SCGB2A2 secretoglobin, family 2A, member 2
SLC12A6 solute carrier family 12 (potassium/chloride transporter), member 6
SLC43A1 solute carrier family 43 (amino acid system L transporter), member 1
SNX15 sorting nexin 15
STX1A syntaxin 1A (brain)
SYNGR3 synaptogyrin 3
TEP1 telomerase-associated protein 1
TGFBR3 transforming growth factor, beta receptor III
TMC5 transmembrane channel-like 5
TNFSF13 tumor necrosis factor (ligand) superfamily, member 13
TPST2 tyrosylprotein sulfotransferase 2
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase
TRDMT1 tRNA aspartic acid methyltransferase 1
TRIM36 tripartite motif containing 36
VIPR1 vasoactive intestinal peptide receptor 1
XYLT1 xylosyltransferase I
XYLT2 xylosyltransferase II
ZMAT4 zinc finger, matrin-type 4
ZNF358 zinc finger protein 358
ZNF551 zinc finger protein 551
ZNF76 zinc finger protein 76
ZSCAN2 zinc finger and SCAN domain containing 2