solasodine-4305 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

194 genes differentially expressed following the solasodine-4305 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADGRG1 adhesion G protein-coupled receptor G1
AIM1L absent in melanoma 1-like
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha
ARTN artemin
ATN1 atrophin 1
ATP11A ATPase, class VI, type 11A
ATP2B4 ATPase, Ca++ transporting, plasma membrane 4
ATRNL1 attractin-like 1
AZGP1 alpha-2-glycoprotein 1, zinc-binding
CALCA calcitonin-related polypeptide alpha
CBS cystathionine-beta-synthase
CCL21 chemokine (C-C motif) ligand 21
CD300C CD300c molecule
CFLAR CASP8 and FADD-like apoptosis regulator
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal)
CLMN calmin (calponin-like, transmembrane)
CMA1 chymase 1, mast cell
CSN3 casein kappa
CTDSPL CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like
CTIF CBP80/20-dependent translation initiation factor
CYP4F12 cytochrome P450, family 4, subfamily F, polypeptide 12
DCN decorin
DMC1 DNA meiotic recombinase 1
DPYSL4 dihydropyrimidinase-like 4
EXPH5 exophilin 5
F13A1 coagulation factor XIII, A1 polypeptide
FCN1 ficolin (collagen/fibrinogen domain containing) 1
FCN2 ficolin (collagen/fibrinogen domain containing lectin) 2
FGL2 fibrinogen-like 2
FUT2 fucosyltransferase 2 (secretor status included)
FUT6 fucosyltransferase 6 (alpha (1,3) fucosyltransferase)
GDF5 growth differentiation factor 5
GHRHR growth hormone releasing hormone receptor
GNL3LP1 guanine nucleotide binding protein-like 3 (nucleolar)-like pseudogene 1
GPR6 G protein-coupled receptor 6
HCAR3 hydroxycarboxylic acid receptor 3
HOPX HOP homeobox
HOXB3 homeobox B3
ID2B inhibitor of DNA binding 2B, dominant negative helix-loop-helix protein (pseudogene)
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
IGF1R insulin-like growth factor 1 receptor
IL11 interleukin 11
INSL4 insulin-like 4 (placenta)
IQSEC2 IQ motif and Sec7 domain 2
IRF2BP1 interferon regulatory factor 2 binding protein 1
JUND jun D proto-oncogene
KDSR 3-ketodihydrosphingosine reductase
LCN1 lipocalin 1
LEPR leptin receptor
LINC00216 long intergenic non-protein coding RNA 216
LMO3 LIM domain only 3 (rhombotin-like 2)
MAP2K7 mitogen-activated protein kinase kinase 7
MAPRE3 microtubule-associated protein, RP/EB family, member 3
MOG myelin oligodendrocyte glycoprotein
MYF5 myogenic factor 5
MYLPF myosin light chain, phosphorylatable, fast skeletal muscle
NCLN nicalin
NCR3 natural cytotoxicity triggering receptor 3
NEUROD6 neuronal differentiation 6
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NPTX2 neuronal pentraxin II
NRXN3 neurexin 3
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
OR2F2 olfactory receptor, family 2, subfamily F, member 2
PKNOX2 PBX/knotted 1 homeobox 2
PLCH2 phospholipase C, eta 2
PLK3 polo-like kinase 3
PLVAP plasmalemma vesicle associated protein
PNMAL1 paraneoplastic Ma antigen family-like 1
PRIM2 primase, DNA, polypeptide 2 (58kDa)
PRKCDBP protein kinase C, delta binding protein
PROL1 proline rich, lacrimal 1
PRPH2 peripherin 2 (retinal degeneration, slow)
PTCH2 patched 2
PTGDS prostaglandin D2 synthase 21kDa (brain)
PYGO1 pygopus family PHD finger 1
RECQL5 RecQ protein-like 5
REPS1 RALBP1 associated Eps domain containing 1
RHAG Rh-associated glycoprotein
SIGLEC5 sialic acid binding Ig-like lectin 5
SLAMF8 SLAM family member 8
SLC9A3R2 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2
SMAD6 SMAD family member 6
SMARCD1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1
SMG7-AS1 SMG7 antisense RNA 1
SPINK5 serine peptidase inhibitor, Kazal type 5
SSTR5 somatostatin receptor 5
SYN3 synapsin III
TMEM74B transmembrane protein 74B
TNS1 tensin 1
TRIL TLR4 interactor with leucine-rich repeats
TRIM3 tripartite motif containing 3
TTC38 tetratricopeptide repeat domain 38
UCP1 uncoupling protein 1 (mitochondrial, proton carrier)
WNT16 wingless-type MMTV integration site family, member 16
ZBTB7A zinc finger and BTB domain containing 7A
ZIM2 zinc finger, imprinted 2

decreased expression

Symbol Name
ACTR8 ARP8 actin-related protein 8 homolog (yeast)
AGO4 argonaute RISC catalytic component 4
ALPK1 alpha-kinase 1
ANXA10 annexin A10
ASAP1-IT1 ASAP1 intronic transcript 1
ATAD5 ATPase family, AAA domain containing 5
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1
BPGM 2,3-bisphosphoglycerate mutase
C3ORF52 chromosome 3 open reading frame 52
CARD8 caspase recruitment domain family, member 8
CHM choroideremia (Rab escort protein 1)
CHST12 carbohydrate (chondroitin 4) sulfotransferase 12
CLEC2B C-type lectin domain family 2, member B
CNIH3 cornichon family AMPA receptor auxiliary protein 3
CNNM1 cyclin and CBS domain divalent metal cation transport mediator 1
COL4A3BP collagen, type IV, alpha 3 (Goodpasture antigen) binding protein
CORT cortistatin
CREB5 cAMP responsive element binding protein 5
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides
DCAF16 DDB1 and CUL4 associated factor 16
DDX6 DEAD (Asp-Glu-Ala-Asp) box helicase 6
ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5
EPHX2 epoxide hydrolase 2, cytoplasmic
FAM169A family with sequence similarity 169, member A
FBXL7 F-box and leucine-rich repeat protein 7
FBXO5 F-box protein 5
FKBPL FK506 binding protein like
GNB1L guanine nucleotide binding protein (G protein), beta polypeptide 1-like
GPALPP1 GPALPP motifs containing 1
GRB2 growth factor receptor-bound protein 2
GUSBP3 glucuronidase, beta pseudogene 3
HIST1H1D histone cluster 1, H1d
HIST1H1E histone cluster 1, H1e
HIST1H2AI histone cluster 1, H2ai
HIST1H4C histone cluster 1, H4c
IER3IP1 immediate early response 3 interacting protein 1
IFI6 interferon, alpha-inducible protein 6
IFITM1 interferon induced transmembrane protein 1
IFT22 intraflagellar transport 22
KBTBD4 kelch repeat and BTB (POZ) domain containing 4
KIAA1551 KIAA1551
KRT15 keratin 15, type I
KRT4 keratin 4, type II
KRT75 keratin 75, type II
LIMS2 LIM and senescent cell antigen-like domains 2
LRRC37A4P leucine rich repeat containing 37, member A4, pseudogene
MANBA mannosidase, beta A, lysosomal
MRPL52 mitochondrial ribosomal protein L52
MTPAP mitochondrial poly(A) polymerase
MX1 MX dynamin-like GTPase 1
MXD3 MAX dimerization protein 3
MYL5 myosin, light chain 5, regulatory
NARFL nuclear prelamin A recognition factor-like
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NFIX nuclear factor I/X (CCAAT-binding transcription factor)
NINJ1 ninjurin 1
NLRX1 NLR family member X1
NUCB2 nucleobindin 2
NUTF2 nuclear transport factor 2
P3H4 prolyl 3-hydroxylase family member 4 (non-enzymatic)
PRKAB2 protein kinase, AMP-activated, beta 2 non-catalytic subunit
PRMT7 protein arginine methyltransferase 7
PROCR protein C receptor, endothelial
PRR14L proline rich 14-like
PTGFR prostaglandin F receptor (FP)
PXMP4 peroxisomal membrane protein 4, 24kDa
RABL6 RAB, member RAS oncogene family-like 6
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
RAI2 retinoic acid induced 2
RASSF8 Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
RBBP5 retinoblastoma binding protein 5
RSRC1 arginine/serine-rich coiled-coil 1
SAMD9 sterile alpha motif domain containing 9
SIX1 SIX homeobox 1
SMAD5 SMAD family member 5
SMG1 SMG1 phosphatidylinositol 3-kinase-related kinase
SPIN1 spindlin 1
SPRYD7 SPRY domain containing 7
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
TGFBRAP1 transforming growth factor, beta receptor associated protein 1
TMEM159 transmembrane protein 159
TTBK2 tau tubulin kinase 2
TUBA3D tubulin, alpha 3d
USP6 ubiquitin specific peptidase 6
WDR25 WD repeat domain 25
XPNPEP3 X-prolyl aminopeptidase 3, mitochondrial
ZBTB38 zinc finger and BTB domain containing 38
ZNF124 zinc finger protein 124
ZNF189 zinc finger protein 189
ZNF385D zinc finger protein 385D
ZNF529 zinc finger protein 529
ZNF606 zinc finger protein 606
ZNF668 zinc finger protein 668
ZNF702P zinc finger protein 702, pseudogene
ZNF767P zinc finger family member 767, pseudogene
ZNF8 zinc finger protein 8