solasodine-6025 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

194 genes differentially expressed following the solasodine-6025 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
A4GNT alpha-1,4-N-acetylglucosaminyltransferase
AADAC arylacetamide deacetylase
ADGRB2 adhesion G protein-coupled receptor B2
ADRA1A adrenoceptor alpha 1A
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
ARHGEF28 Rho guanine nucleotide exchange factor (GEF) 28
ATN1 atrophin 1
BIN1 bridging integrator 1
CAMKV CaM kinase-like vesicle-associated
CD52 CD52 molecule
CD70 CD70 molecule
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
CEND1 cell cycle exit and neuronal differentiation 1
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CIZ1 CDKN1A interacting zinc finger protein 1
CNTNAP2 contactin associated protein-like 2
COL5A2 collagen, type V, alpha 2
CR1 complement component (3b/4b) receptor 1 (Knops blood group)
CUL3 cullin 3
CXCR4 chemokine (C-X-C motif) receptor 4
DUX1 double homeobox 1
E2F2 E2F transcription factor 2
EDA ectodysplasin A
ELL2 elongation factor, RNA polymerase II, 2
EPX eosinophil peroxidase
ERAP1 endoplasmic reticulum aminopeptidase 1
ERC2-IT1 ERC2 intronic transcript 1
FCER1A Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide
FCGR2C Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene)
FUT6 fucosyltransferase 6 (alpha (1,3) fucosyltransferase)
GIMAP6 GTPase, IMAP family member 6
GRIN2A glutamate receptor, ionotropic, N-methyl D-aspartate 2A
GSK3A glycogen synthase kinase 3 alpha
HBB hemoglobin, beta
HEMK1 HemK methyltransferase family member 1
HLF hepatic leukemia factor
HNF1A HNF1 homeobox A
HNRNPD heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa)
HRASLS HRAS-like suppressor
IFNW1 interferon, omega 1
IL23A interleukin 23, alpha subunit p19
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KHDRBS2 KH domain containing, RNA binding, signal transduction associated 2
LAMB4 laminin, beta 4
LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
LILRB4 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 4
LRCH4 leucine-rich repeats and calponin homology (CH) domain containing 4
LRRN3 leucine rich repeat neuronal 3
MAGEA6 melanoma antigen family A6
MATN1 matrilin 1, cartilage matrix protein
MMP19 matrix metallopeptidase 19
MNDA myeloid cell nuclear differentiation antigen
MPL MPL proto-oncogene, thrombopoietin receptor
MUC5AC mucin 5AC, oligomeric mucus/gel-forming
MZF1 myeloid zinc finger 1
NAG18 NAG18 mRNA
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NEB nebulin
NEUROG2 neurogenin 2
NIPAL3 NIPA-like domain containing 3
NLRP3 NLR family, pyrin domain containing 3
NPHS1 nephrosis 1, congenital, Finnish type (nephrin)
NR2E3 nuclear receptor subfamily 2, group E, member 3
NTS neurotensin
PART1 prostate androgen-regulated transcript 1 (non-protein coding)
PIEZO2 piezo-type mechanosensitive ion channel component 2
PLA2G4C phospholipase A2, group IVC (cytosolic, calcium-independent)
PRDM10 PR domain containing 10
PTPRM protein tyrosine phosphatase, receptor type, M
RCE1 Ras converting CAAX endopeptidase 1
RGS12 regulator of G-protein signaling 12
RHBG Rh family, B glycoprotein (gene/pseudogene)
RNF126P1 ring finger protein 126 pseudogene 1
RNPEPL1 arginyl aminopeptidase (aminopeptidase B)-like 1
RORC RAR-related orphan receptor C
RPL23AP32 ribosomal protein L23a pseudogene 32
RTN2 reticulon 2
S100A1 S100 calcium binding protein A1
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1
SLC1A7 solute carrier family 1 (glutamate transporter), member 7
SLC48A1 solute carrier family 48 (heme transporter), member 1
SPTLC3 serine palmitoyltransferase, long chain base subunit 3
SRD5A2 steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2)
SSX1 synovial sarcoma, X breakpoint 1
STMN2 stathmin 2
TBC1D1 TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1
THAP3 THAP domain containing, apoptosis associated protein 3
TKTL1 transketolase-like 1
TM4SF4 transmembrane 4 L six family member 4
TM4SF5 transmembrane 4 L six family member 5
TNP2 transition protein 2 (during histone to protamine replacement)
TRAK1 trafficking protein, kinesin binding 1
TSC22D4 TSC22 domain family, member 4
UTS2 urotensin 2
ZFP2 ZFP2 zinc finger protein
ZNF215 zinc finger protein 215

decreased expression

Symbol Name
ACSF2 acyl-CoA synthetase family member 2
ACTL8 actin-like 8
ADGRA3 adhesion G protein-coupled receptor A3
ADM adrenomedullin
AKR1C2 aldo-keto reductase family 1, member C2
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta
ARTN artemin
ASAP1-IT1 ASAP1 intronic transcript 1
ASB7 ankyrin repeat and SOCS box containing 7
ASPHD1 aspartate beta-hydroxylase domain containing 1
BBS7 Bardet-Biedl syndrome 7
BCL9 B-cell CLL/lymphoma 9
BPHL biphenyl hydrolase-like (serine hydrolase)
C7ORF43 chromosome 7 open reading frame 43
CA5BP1 carbonic anhydrase VB pseudogene 1
CDK3 cyclin-dependent kinase 3
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CHKB choline kinase beta
CHML choroideremia-like (Rab escort protein 2)
CLDN15 claudin 15
CXCL12 chemokine (C-X-C motif) ligand 12
CXORF56 chromosome X open reading frame 56
E2F6 E2F transcription factor 6
EGR3 early growth response 3
EHMT1 euchromatic histone-lysine N-methyltransferase 1
EPHA2 EPH receptor A2
F3 coagulation factor III (thromboplastin, tissue factor)
FYCO1 FYVE and coiled-coil domain containing 1
GCHFR GTP cyclohydrolase I feedback regulator
GLCE glucuronic acid epimerase
GPR19 G protein-coupled receptor 19
HIST1H2AG histone cluster 1, H2ag
HIST1H2AI histone cluster 1, H2ai
HIST1H4D histone cluster 1, H4d
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HS3ST3A1 heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1
HSPBAP1 HSPB (heat shock 27kDa) associated protein 1
IER3 immediate early response 3
IL15RA interleukin 15 receptor, alpha
INO80D INO80 complex subunit D
LINS lines homolog (Drosophila)
MAN1A1 mannosidase, alpha, class 1A, member 1
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
METTL16 methyltransferase like 16
MINOS1P1 mitochondrial inner membrane organizing system 1 pseudogene 1
MPP6 membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6)
MPPED2 metallophosphoesterase domain containing 2
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
MTCL1 microtubule crosslinking factor 1
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1
MYO1D myosin ID
NAA38 N(alpha)-acetyltransferase 38, NatC auxiliary subunit
NDST2 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2
NOD1 nucleotide-binding oligomerization domain containing 1
NOL10 nucleolar protein 10
NOL12 nucleolar protein 12
NPIPB3 nuclear pore complex interacting protein family, member B3
NPL N-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase)
NPY1R neuropeptide Y receptor Y1
PCDHA9 protocadherin alpha 9
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta)
POLR3D polymerase (RNA) III (DNA directed) polypeptide D, 44kDa
POMT2 protein-O-mannosyltransferase 2
PRKX protein kinase, X-linked
PROS1 protein S (alpha)
PRPH peripherin
RAD51AP1 RAD51 associated protein 1
RALGPS2 Ral GEF with PH domain and SH3 binding motif 2
RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated)
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
RHOBTB1 Rho-related BTB domain containing 1
RNF121 ring finger protein 121
RPIA ribose 5-phosphate isomerase A
SEC24B SEC24 family member B
SGK1 serum/glucocorticoid regulated kinase 1
SLC41A3 solute carrier family 41, member 3
SLC6A14 solute carrier family 6 (amino acid transporter), member 14
SPAG4 sperm associated antigen 4
STRA6 stimulated by retinoic acid 6
STRN striatin, calmodulin binding protein
SYBU syntabulin (syntaxin-interacting)
TDRD1 tudor domain containing 1
TGDS TDP-glucose 4,6-dehydratase
THNSL1 threonine synthase-like 1 (S. cerevisiae)
TICAM1 toll-like receptor adaptor molecule 1
TPST2 tyrosylprotein sulfotransferase 2
TTF2 transcription termination factor, RNA polymerase II
USB1 U6 snRNA biogenesis 1
WDR3 WD repeat domain 3
ZBTB3 zinc finger and BTB domain containing 3
ZNF184 zinc finger protein 184
ZNF189 zinc finger protein 189
ZNF239 zinc finger protein 239
ZNF34 zinc finger protein 34
ZNF468 zinc finger protein 468
ZNF480 zinc finger protein 480
ZNF767P zinc finger family member 767, pseudogene
ZNHIT2 zinc finger, HIT-type containing 2