solution Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
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Genes

355 genes co-occuring with the biological term solution in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase
ABRACL ABRA C-terminal like
ACO1 aconitase 1, soluble
ACTN1 actinin, alpha 1
AGER advanced glycosylation end product-specific receptor
AIRE autoimmune regulator
ALB albumin
AMELX amelogenin, X-linked
ANP32A acidic (leucine-rich) nuclear phosphoprotein 32 family, member A
ANXA2 annexin A2
APLF aprataxin and PNKP like factor
APOA1 apolipoprotein A-I
APOBEC3G apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G
APOE apolipoprotein E
APOH apolipoprotein H (beta-2-glycoprotein I)
APP amyloid beta (A4) precursor protein
ARF1 ADP-ribosylation factor 1
ARID3A AT rich interactive domain 3A (BRIGHT-like)
ARIH1 ariadne RBR E3 ubiquitin protein ligase 1
ATOX1 antioxidant 1 copper chaperone
ATP2B1 ATPase, Ca++ transporting, plasma membrane 1
ATP7A ATPase, Cu++ transporting, alpha polypeptide
ATP7B ATPase, Cu++ transporting, beta polypeptide
ATXN7 ataxin 7
ATXN7L3 ataxin 7-like 3
B2M beta-2-microglobulin
BAD BCL2-associated agonist of cell death
BAK1 BCL2-antagonist/killer 1
BCL2L1 BCL2-like 1
BCR breakpoint cluster region
BID BH3 interacting domain death agonist
BMP2 bone morphogenetic protein 2
BMPR1A bone morphogenetic protein receptor, type IA
BRCA1 breast cancer 1, early onset
BRD2 bromodomain containing 2
BRD4 bromodomain containing 4
BTC betacellulin
CAD carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
CALM1 calmodulin 1 (phosphorylase kinase, delta)
CAMP cathelicidin antimicrobial peptide
CARTPT CART prepropeptide
CAST calpastatin
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CBY1 chibby homolog 1 (Drosophila)
CCS copper chaperone for superoxide dismutase
CD247 CD247 molecule
CD2AP CD2-associated protein
CD4 CD4 molecule
CD44 CD44 molecule (Indian blood group)
CD5 CD5 molecule
CD8A CD8a molecule
CD99 CD99 molecule
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CETN2 centrin, EF-hand protein, 2
CFH complement factor H
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
CHURC1 churchill domain containing 1
CIB1 calcium and integrin binding 1 (calmyrin)
CLIC1 chloride intracellular channel 1
CNR1 cannabinoid receptor 1 (brain)
COL1A1 collagen, type I, alpha 1
COMMD1 copper metabolism (Murr1) domain containing 1
COPZ2 coatomer protein complex, subunit zeta 2
CP ceruloplasmin (ferroxidase)
CPA2 carboxypeptidase A2 (pancreatic)
CR1 complement component (3b/4b) receptor 1 (Knops blood group)
CR2 complement component (3d/Epstein Barr virus) receptor 2
CREBBP CREB binding protein
CRK v-crk avian sarcoma virus CT10 oncogene homolog
CRY2 cryptochrome circadian clock 2
CTDP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
CXCL5 chemokine (C-X-C motif) ligand 5
CXCL8 chemokine (C-X-C motif) ligand 8
CXCR1 chemokine (C-X-C motif) receptor 1
DBT dihydrolipoamide branched chain transacylase E2
DCN decorin
DDX50 DEAD (Asp-Glu-Ala-Asp) box polypeptide 50
DEFB1 defensin, beta 1
DEFB103B defensin, beta 103B
DEFB4A defensin, beta 4A
DEK DEK proto-oncogene
DFFA DNA fragmentation factor, 45kDa, alpha polypeptide
DHFR dihydrofolate reductase
DLAT dihydrolipoamide S-acetyltransferase
DMD dystrophin
DNAJC24 DnaJ (Hsp40) homolog, subfamily C, member 24
DOCK1 dedicator of cytokinesis 1
DPF3 D4, zinc and double PHD fingers, family 3
DPH3 diphthamide biosynthesis 3
DYSF dysferlin
EEF1B2P2 eukaryotic translation elongation factor 1 beta 2 pseudogene 2
EGF epidermal growth factor
EHD1 EH-domain containing 1
EIF4B eukaryotic translation initiation factor 4B
EIF5 eukaryotic translation initiation factor 5
ELAVL1 ELAV like RNA binding protein 1
ELN elastin
ENG endoglin
EP300 E1A binding protein p300
EPHA2 EPH receptor A2
ETFA electron-transfer-flavoprotein, alpha polypeptide
F11 coagulation factor XI
F12 coagulation factor XII (Hageman factor)
F7 coagulation factor VII (serum prothrombin conversion accelerator)
F8 coagulation factor VIII, procoagulant component
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FADD Fas (TNFRSF6)-associated via death domain
FAS Fas cell surface death receptor
FEZ1 fasciculation and elongation protein zeta 1 (zygin I)
FGF2 fibroblast growth factor 2 (basic)
FN1 fibronectin 1
GABARAP GABA(A) receptor-associated protein
GC group-specific component (vitamin D binding protein)
GCG glucagon
GGPS1 geranylgeranyl diphosphate synthase 1
GH1 growth hormone 1
GIP gastric inhibitory polypeptide
GLRX2 glutaredoxin 2
GNB2L1 guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1
GP1BA glycoprotein Ib (platelet), alpha polypeptide
GRB7 growth factor receptor-bound protein 7
GRN granulin
GSTT1 glutathione S-transferase theta 1
GTF2E1 general transcription factor IIE, polypeptide 1, alpha 56kDa
GTF2E2 general transcription factor IIE, polypeptide 2, beta 34kDa
GTF2F1 general transcription factor IIF, polypeptide 1, 74kDa
GTF2H2 general transcription factor IIH, polypeptide 2, 44kDa
GTF2H5 general transcription factor IIH, polypeptide 5
HAMP hepcidin antimicrobial peptide
HAPLN1 hyaluronan and proteoglycan link protein 1
HBA1 hemoglobin, alpha 1
HCK HCK proto-oncogene, Src family tyrosine kinase
HFE hemochromatosis
HHEX hematopoietically expressed homeobox
HIST4H4 histone cluster 4, H4
HMOX1 heme oxygenase 1
HNRNPF heterogeneous nuclear ribonucleoprotein F
HPX hemopexin
HRAS Harvey rat sarcoma viral oncogene homolog
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1
HSPA8 heat shock 70kDa protein 8
HSPB1 heat shock 27kDa protein 1
HSPB6 heat shock protein, alpha-crystallin-related, B6
HSPD1 heat shock 60kDa protein 1 (chaperonin)
HTT huntingtin
IAPP islet amyloid polypeptide
ICAM1 intercellular adhesion molecule 1
IFNB1 interferon, beta 1, fibroblast
IGF1 insulin-like growth factor 1 (somatomedin C)
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
IGHA1 immunoglobulin heavy constant alpha 1
IGHMBP2 immunoglobulin mu binding protein 2
IL1B interleukin 1, beta
IL1RAP interleukin 1 receptor accessory protein
IL33 interleukin 33
INSL3 insulin-like 3 (Leydig cell)
IRS1 insulin receptor substrate 1
ITGA2B integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
ITGAV integrin, alpha V
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
JAG1 jagged 1
KAT2B K(lysine) acetyltransferase 2B
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1
KCTD5 potassium channel tetramerization domain containing 5
KIRREL kin of IRRE like (Drosophila)
KLF1 Kruppel-like factor 1 (erythroid)
KMT2A lysine (K)-specific methyltransferase 2A
KMT2E lysine (K)-specific methyltransferase 2E
L3MBTL2 l(3)mbt-like 2 (Drosophila)
LALBA lactalbumin, alpha-
LAMC1 laminin, gamma 1 (formerly LAMB2)
LCK LCK proto-oncogene, Src family tyrosine kinase
LCN1 lipocalin 1
LGALS8 lectin, galactoside-binding, soluble, 8
LIN7C lin-7 homolog C (C. elegans)
LMNA lamin A/C
LTF lactotransferrin
MAD2L2 MAD2 mitotic arrest deficient-like 2 (yeast)
MALT1 MALT1 paracaspase
MAP2K6 mitogen-activated protein kinase kinase 6
MAPT microtubule-associated protein tau
MBNL2 muscleblind-like splicing regulator 2
MBP myelin basic protein
MC4R melanocortin 4 receptor
MCL1 myeloid cell leukemia 1
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MED25 mediator complex subunit 25
MFGE8 milk fat globule-EGF factor 8 protein
MIA melanoma inhibitory activity
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor)
MKI67 marker of proliferation Ki-67
MLLT4 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4
MMP1 matrix metallopeptidase 1
MMP13 matrix metallopeptidase 13
MMP2 matrix metallopeptidase 2
MOG myelin oligodendrocyte glycoprotein
MSMB microseminoprotein, beta-
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MUC5B mucin 5B, oligomeric mucus/gel-forming
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYD88 myeloid differentiation primary response 88
MYOF myoferlin
MYOT myotilin
N4BP2 NEDD4 binding protein 2
NDUFA2 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2, 8kDa
NEK6 NIMA-related kinase 6
NHP2L1 NHP2 non-histone chromosome protein 2-like 1 (S. cerevisiae)
NIFK nucleolar protein interacting with the FHA domain of MKI67
NLRC5 NLR family, CARD domain containing 5
NOD1 nucleotide-binding oligomerization domain containing 1
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin)
NRXN1 neurexin 1
NUDT1 nudix (nucleoside diphosphate linked moiety X)-type motif 1
NUP210 nucleoporin 210kDa
OARD1 O-acyl-ADP-ribose deacylase 1
OST4 oligosaccharyltransferase 4 homolog (S. cerevisiae)
PCNA proliferating cell nuclear antigen
PDIA2 protein disulfide isomerase family A, member 2
PEA15 phosphoprotein enriched in astrocytes 15
PGLYRP1 peptidoglycan recognition protein 1
PHPT1 phosphohistidine phosphatase 1
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1
PITX2 paired-like homeodomain 2
PLEK pleckstrin
PLG plasminogen
PLXNB1 plexin B1
PMCH pro-melanin-concentrating hormone
PNLIP pancreatic lipase
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit
POLI polymerase (DNA directed) iota
POLL polymerase (DNA directed), lambda
POLR2F polymerase (RNA) II (DNA directed) polypeptide F
PPARG peroxisome proliferator-activated receptor gamma
PPIL1 peptidylprolyl isomerase (cyclophilin)-like 1
PPP1R11 protein phosphatase 1, regulatory (inhibitor) subunit 11
PPP1R12A protein phosphatase 1, regulatory subunit 12A
PPP1R7 protein phosphatase 1, regulatory subunit 7
PPP5C protein phosphatase 5, catalytic subunit
PRG4 proteoglycan 4
PRKDC protein kinase, DNA-activated, catalytic polypeptide
PRL prolactin
PRPF18 pre-mRNA processing factor 18
PSMD2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2
PTBP1 polypyrimidine tract binding protein 1
PTGER2 prostaglandin E receptor 2 (subtype EP2), 53kDa
PTGIS prostaglandin I2 (prostacyclin) synthase
PTK6 protein tyrosine kinase 6
PTP4A3 protein tyrosine phosphatase type IVA, member 3
PTPN13 protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase)
PTPN4 protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte)
PTPRK protein tyrosine phosphatase, receptor type, K
PUF60 poly-U binding splicing factor 60KDa
QRFP pyroglutamylated RFamide peptide
RACGAP1 Rac GTPase activating protein 1
RAD23A RAD23 homolog A (S. cerevisiae)
RAD23B RAD23 homolog B (S. cerevisiae)
RBCK1 RanBP-type and C3HC4-type zinc finger containing 1
REG4 regenerating islet-derived family, member 4
REV1 REV1, polymerase (DNA directed)
RLN3 relaxin 3
RNF111 ring finger protein 111
RNR2 RNA, ribosomal cluster 2
RNU12-2P RNA, U12 small nuclear 2, pseudogene
RPLP2 ribosomal protein, large, P2
RXRA retinoid X receptor, alpha
S100A14 S100 calcium binding protein A14
S100A4 S100 calcium binding protein A4
S100A5 S100 calcium binding protein A5
S100A9 S100 calcium binding protein A9
S100B S100 calcium binding protein B
SBDS Shwachman-Bodian-Diamond syndrome
SCN5A sodium channel, voltage gated, type V alpha subunit
SCT secretin
SEMG1 semenogelin I
SEPT8 septin 8
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SERPIND1 serpin peptidase inhibitor, clade D (heparin cofactor), member 1
SETD2 SET domain containing 2
SF3B1 splicing factor 3b, subunit 1, 155kDa
SFTPC surfactant protein C
SH3KBP1 SH3-domain kinase binding protein 1
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
SLC2A4 solute carrier family 2 (facilitated glucose transporter), member 4
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SOD1 superoxide dismutase 1, soluble
SOX4 SRY (sex determining region Y)-box 4
SPAST spastin
SPP1 secreted phosphoprotein 1
SPTA1 spectrin, alpha, erythrocytic 1
SQSTM1 sequestosome 1
STAM2 signal transducing adaptor molecule (SH3 domain and ITAM motif) 2
STAT1 signal transducer and activator of transcription 1, 91kDa
STC1 stanniocalcin 1
SVIL supervillin
SVIP small VCP/p97-interacting protein
SYVN1 synovial apoptosis inhibitor 1, synoviolin
TADA2A transcriptional adaptor 2A
TBP TATA box binding protein
TERC telomerase RNA component
TFF3 trefoil factor 3 (intestinal)
TH tyrosine hydroxylase
THBS1 thrombospondin 1
THRB thyroid hormone receptor, beta
TJP1 tight junction protein 1
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A
TNFRSF21 tumor necrosis factor receptor superfamily, member 21
TNFSF13B tumor necrosis factor (ligand) superfamily, member 13b
TNFSF18 tumor necrosis factor (ligand) superfamily, member 18
TOP1 topoisomerase (DNA) I
TP53 tumor protein p53
TP63 tumor protein p63
TREM1 triggering receptor expressed on myeloid cells 1
TSG101 tumor susceptibility 101
TSN translin
TXNDC12 thioredoxin domain containing 12 (endoplasmic reticulum)
TXNL1 thioredoxin-like 1
U2AF1 U2 small nuclear RNA auxiliary factor 1
U2AF2 U2 small nuclear RNA auxiliary factor 2
UBA3 ubiquitin-like modifier activating enzyme 3
UBE2E1 ubiquitin-conjugating enzyme E2E 1
UBE2G2 ubiquitin-conjugating enzyme E2G 2
UBL7 ubiquitin-like 7
UBLCP1 ubiquitin-like domain containing CTD phosphatase 1
UBQLN1 ubiquilin 1
UBQLN2 ubiquilin 2
UBR5 ubiquitin protein ligase E3 component n-recognin 5
UBTD2 ubiquitin domain containing 2
UBTF upstream binding transcription factor, RNA polymerase I
UFM1 ubiquitin-fold modifier 1
USP16 ubiquitin specific peptidase 16
USP33 ubiquitin specific peptidase 33
UTS2R urotensin 2 receptor
UXS1 UDP-glucuronate decarboxylase 1
VASP vasodilator-stimulated phosphoprotein
VCAM1 vascular cell adhesion molecule 1
VCAN versican
VCP valosin containing protein
VDAC1 voltage-dependent anion channel 1
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
VEGFA vascular endothelial growth factor A
VPS4A vacuolar protein sorting 4 homolog A (S. cerevisiae)
VRK1 vaccinia related kinase 1
VSNL1 visinin-like 1
VTN vitronectin
VWF von Willebrand factor
WRN Werner syndrome, RecQ helicase-like
XCL1 chemokine (C motif) ligand 1
YWHAG tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma
ZBP1 Z-DNA binding protein 1
ZBTB17 zinc finger and BTB domain containing 17
ZBTB32 zinc finger and BTB domain containing 32
ZFP36 ZFP36 ring finger protein