somatic hypermutation of immunoglobulin genes Gene Set

Dataset GO Biological Process Annotations
Category structural or functional annotations
Type biological process
Description Mutations occurring somatically that result in amino acid changes in the rearranged V regions of immunoglobulins. (Gene Ontology, GO_0016446)
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11 genes participating in the somatic hypermutation of immunoglobulin genes biological process from the curated GO Biological Process Annotations dataset.

Symbol Name
AICDA activation-induced cytidine deaminase
EXO1 exonuclease 1
MLH1 mutL homolog 1
MSH2 mutS homolog 2
MSH6 mutS homolog 6
NUGGC nuclear GTPase, germinal center associated
PMS2 PMS2 postmeiotic segregation increased 2 (S. cerevisiae)
POLL polymerase (DNA directed), lambda
POLM polymerase (DNA directed), mu
POLQ polymerase (DNA directed), theta
UNG uracil-DNA glycosylase