somatic hypermutation of immunoglobulin genes Gene Set

Dataset	GO Biological Process Annotations 2025
Category	structural or functional annotations
Type	biological process
Description	Mutations occurring somatically that result in amino acid changes in the rearranged V regions of immunoglobulins. (Gene Ontology, GO_0016446)
External Link	http://amigo.geneontology.org/amigo/term/GO:0016446
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Genes

9 genes participating in the somatic hypermutation of immunoglobulin genes biological process from the curated GO Biological Process Annotations 2025 dataset.

Symbol	Name
AICDA	activation-induced cytidine deaminase
HMCES	5-hydroxymethylcytosine (hmC) binding, ES cell-specific
MCM3AP	minichromosome maintenance complex component 3 associated protein
MLH1	mutL homolog 1
MSH6	mutS homolog 6
PMS2	PMS2 postmeiotic segregation increased 2 (S. cerevisiae)
POLK	polymerase (DNA directed) kappa
POLL	polymerase (DNA directed), lambda
SAMHD1	SAM domain and HD domain 1