sorafenib Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
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Genes

69 genes co-occuring with the biological term sorafenib in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ABCC10 ATP-binding cassette, sub-family C (CFTR/MRP), member 10
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group)
AFP alpha-fetoprotein
AKT1 v-akt murine thymoma viral oncogene homolog 1
BAK1 BCL2-antagonist/killer 1
BBC3 BCL2 binding component 3
BCL2L1 BCL2-like 1
BCL2L11 BCL2-like 11 (apoptosis facilitator)
BRAF B-Raf proto-oncogene, serine/threonine kinase
CA9 carbonic anhydrase IX
CASP3 caspase 3, apoptosis-related cysteine peptidase
CASP7 caspase 7, apoptosis-related cysteine peptidase
CCNC cyclin C
CCND1 cyclin D1
CD44 CD44 molecule (Indian blood group)
CDK8 cyclin-dependent kinase 8
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CXCR4 chemokine (C-X-C motif) receptor 4
CYCS cytochrome c, somatic
CYP3A7 cytochrome P450, family 3, subfamily A, polypeptide 7
EGFR epidermal growth factor receptor
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3
EIF2S1 eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa
ELK1 ELK1, member of ETS oncogene family
EPAS1 endothelial PAS domain protein 1
ERBB2 erb-b2 receptor tyrosine kinase 2
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit
FAS Fas cell surface death receptor
FLT3 fms-related tyrosine kinase 3
FOS FBJ murine osteosarcoma viral oncogene homolog
GADD45B growth arrest and DNA-damage-inducible, beta
GSK3B glycogen synthase kinase 3 beta
HDAC9 histone deacetylase 9
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HRAS Harvey rat sarcoma viral oncogene homolog
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KRAS Kirsten rat sarcoma viral oncogene homolog
MAPK1 mitogen-activated protein kinase 1
MAPK14 mitogen-activated protein kinase 14
MAPK3 mitogen-activated protein kinase 3
MAPK8 mitogen-activated protein kinase 8
MCL1 myeloid cell leukemia 1
MIR193B microRNA 193b
MTOR mechanistic target of rapamycin (serine/threonine kinase)
NFE2L2 nuclear factor, erythroid 2-like 2
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
OPA1 optic atrophy 1 (autosomal dominant)
PARP1 poly (ADP-ribose) polymerase 1
PDGFB platelet-derived growth factor beta polypeptide
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PDGFRB platelet-derived growth factor receptor, beta polypeptide
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
RAF1 Raf-1 proto-oncogene, serine/threonine kinase
RB1 retinoblastoma 1
RET ret proto-oncogene
RRM1 ribonucleotide reductase M1
S100A4 S100 calcium binding protein A4
SLC22A1 solute carrier family 22 (organic cation transporter), member 1
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
TGFBR1 transforming growth factor, beta receptor 1
THBS1 thrombospondin 1
TP53 tumor protein p53
UGT1A1 UDP glucuronosyltransferase 1 family, polypeptide A1
UGT1A9 UDP glucuronosyltransferase 1 family, polypeptide A9
VEGFA vascular endothelial growth factor A
ZAK sterile alpha motif and leucine zipper containing kinase AZK