son of sevenless homolog 1 (Drosophila)|This gene encodes a protein that is a guanine nucleotide exchange factor for RAS proteins, membrane proteins that bind guanine nucleotides and participate in signal transduction pathways. GTP binding activates and GTP hydrolysis inactivates RAS proteins. The product of this gene may regulate RAS proteins by facilitating the exchange of GTP for GDP. Mutations in this gene are associated with gingival fibromatosis 1 and Noonan syndrome type 4. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 6654)
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9 genes co-occuring with the biological term sos1 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.
