sost-related sclerosing bone dysplasia Gene Set

Dataset DISEASES Text-mining Gene-Disease Assocation Evidence Scores
Category disease or phenotype associations
Type disease
Description A hyperostosis that has_material_basis_in a mutation in the SOST gene which results_in overgrowth of endosteal bone producing dense and wide bones throughout the body especially located_in skull. (Human Disease Ontology, DOID_0080036)
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Genes

51 genes co-occuring with the disease sost-related sclerosing bone dysplasia in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
SOST sclerostin 3.00358
LRP5 low density lipoprotein receptor-related protein 5 2.0859
LRP6 low density lipoprotein receptor-related protein 6 1.68226
MEF2C myocyte enhancer factor 2C 1.18884
SRP9P1 signal recognition particle 9 pseudogene 1 1.16221
SRP9 signal recognition particle 9kDa 1.16221
MEOX1 mesenchyme homeobox 1 1.08118
GPHA2 glycoprotein hormone alpha 2 1.06354
WNT3A wingless-type MMTV integration site family, member 3A 1.03367
KREMEN1 kringle containing transmembrane protein 1 1.00879
NOG noggin 0.979689
SP7 Sp7 transcription factor 0.97254
SOSTDC1 sclerostin domain containing 1 0.928346
DKK1 dickkopf WNT signaling pathway inhibitor 1 0.928346
WNT1 wingless-type MMTV integration site family, member 1 0.925865
YIPF2 Yip1 domain family, member 2 0.918848
PTGER2 prostaglandin E receptor 2 (subtype EP2), 53kDa 0.819206
CHRD chordin 0.734217
BMP6 bone morphogenetic protein 6 0.727738
WNT7B wingless-type MMTV integration site family, member 7B 0.673518
LRP4 low density lipoprotein receptor-related protein 4 0.667152
RUNX2 runt-related transcription factor 2 0.639463
MEF2A myocyte enhancer factor 2A 0.633169
DOK7 docking protein 7 0.625319
ADAM28 ADAM metallopeptidase domain 28 0.623359
BMP1 bone morphogenetic protein 1 0.594843
DLX5 distal-less homeobox 5 0.589001
BGLAP bone gamma-carboxyglutamate (gla) protein 0.580439
YIPF1 Yip1 domain family, member 1 0.579661
RAPSN receptor-associated protein of the synapse 0.566831
GREM1 gremlin 1, DAN family BMP antagonist 0.5645
LOXL2 lysyl oxidase-like 2 0.522659
MYEF2 myelin expression factor 2 0.501909
COL1A1 collagen, type I, alpha 1 0.470332
GREM2 gremlin 2, DAN family BMP antagonist 0.442418
LDLR low density lipoprotein receptor 0.426265
COL1A2 collagen, type I, alpha 2 0.395235
ALPPL2 alkaline phosphatase, placental-like 2 0.384822
ALPP alkaline phosphatase, placental 0.384451
ALPL alkaline phosphatase, liver/bone/kidney 0.384079
FGF8 fibroblast growth factor 8 (androgen-induced) 0.378885
TRPV4 transient receptor potential cation channel, subfamily V, member 4 0.378143
MSX2 msh homeobox 2 0.368518
AXIN2 axin 2 0.362978
PTH parathyroid hormone 0.348614
GLI3 GLI family zinc finger 3 0.337608
PHEX phosphate regulating endopeptidase homolog, X-linked 0.336144
LEF1 lymphoid enhancer-binding factor 1 0.318635
BMP7 bone morphogenetic protein 7 0.192657
SOX9 SRY (sex determining region Y)-box 9 0.170299
MUSK muscle, skeletal, receptor tyrosine kinase 0.169091
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