| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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194 genes differentially expressed following the sotalol-2918 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCA2 | ATP-binding cassette, sub-family A (ABC1), member 2 |
| AMPD3 | adenosine monophosphate deaminase 3 |
| ANGPT4 | angiopoietin 4 |
| APOC1 | apolipoprotein C-I |
| APOL2 | apolipoprotein L, 2 |
| ARSA | arylsulfatase A |
| ATP13A2 | ATPase type 13A2 |
| ATP9A | ATPase, class II, type 9A |
| CACNB1 | calcium channel, voltage-dependent, beta 1 subunit |
| CAMK4 | calcium/calmodulin-dependent protein kinase IV |
| CCDC9 | coiled-coil domain containing 9 |
| CD1A | CD1a molecule |
| CD6 | CD6 molecule |
| CDKN2A | cyclin-dependent kinase inhibitor 2A |
| CDON | cell adhesion associated, oncogene regulated |
| CECR1 | cat eye syndrome chromosome region, candidate 1 |
| CLCF1 | cardiotrophin-like cytokine factor 1 |
| CLEC4A | C-type lectin domain family 4, member A |
| COL6A1 | collagen, type VI, alpha 1 |
| CRABP2 | cellular retinoic acid binding protein 2 |
| CRAT | carnitine O-acetyltransferase |
| CXCR3 | chemokine (C-X-C motif) receptor 3 |
| DNMT3A | DNA (cytosine-5-)-methyltransferase 3 alpha |
| DOCK6 | dedicator of cytokinesis 6 |
| EXOSC2 | exosome component 2 |
| EXTL3 | exostosin-like glycosyltransferase 3 |
| FCGR3B | Fc fragment of IgG, low affinity IIIb, receptor (CD16b) |
| FUT7 | fucosyltransferase 7 (alpha (1,3) fucosyltransferase) |
| FXYD7 | FXYD domain containing ion transport regulator 7 |
| GCNT3 | glucosaminyl (N-acetyl) transferase 3, mucin type |
| GGA3 | golgi-associated, gamma adaptin ear containing, ARF binding protein 3 |
| GLP1R | glucagon-like peptide 1 receptor |
| GRPR | gastrin-releasing peptide receptor |
| HDC | histidine decarboxylase |
| HEG1 | heart development protein with EGF-like domains 1 |
| HEMK1 | HemK methyltransferase family member 1 |
| HIGD2A | HIG1 hypoxia inducible domain family, member 2A |
| HLA-DPB1 | major histocompatibility complex, class II, DP beta 1 |
| HOXA11 | homeobox A11 |
| HOXD1 | homeobox D1 |
| HSD11B1 | hydroxysteroid (11-beta) dehydrogenase 1 |
| IDH3G | isocitrate dehydrogenase 3 (NAD+) gamma |
| IGFBP5 | insulin-like growth factor binding protein 5 |
| IGHM | immunoglobulin heavy constant mu |
| IL11 | interleukin 11 |
| INE1 | inactivation escape 1 (non-protein coding) |
| LAMA5 | laminin, alpha 5 |
| LEFTY1 | left-right determination factor 1 |
| LRFN4 | leucine rich repeat and fibronectin type III domain containing 4 |
| MAPK8IP1 | mitogen-activated protein kinase 8 interacting protein 1 |
| MDFI | MyoD family inhibitor |
| MLPH | melanophilin |
| MUC3A | mucin 3A, cell surface associated |
| MUC6 | mucin 6, oligomeric mucus/gel-forming |
| MYLPF | myosin light chain, phosphorylatable, fast skeletal muscle |
| NEBL | nebulette |
| NFKBIB | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta |
| NOP14-AS1 | NOP14 antisense RNA 1 |
| NPFFR1 | neuropeptide FF receptor 1 |
| OVGP1 | oviductal glycoprotein 1, 120kDa |
| PACS1 | phosphofurin acidic cluster sorting protein 1 |
| PCDHGA10 | protocadherin gamma subfamily A, 10 |
| PEX10 | peroxisomal biogenesis factor 10 |
| PIEZO2 | piezo-type mechanosensitive ion channel component 2 |
| PKD1 | polycystic kidney disease 1 (autosomal dominant) |
| PLSCR3 | phospholipid scramblase 3 |
| PMCHL1 | pro-melanin-concentrating hormone-like 1, pseudogene |
| PPP2R3A | protein phosphatase 2, regulatory subunit B'', alpha |
| PROL1 | proline rich, lacrimal 1 |
| RASGRP2 | RAS guanyl releasing protein 2 (calcium and DAG-regulated) |
| RNF17 | ring finger protein 17 |
| RNF39 | ring finger protein 39 |
| RPL7 | ribosomal protein L7 |
| RSPH14 | radial spoke head 14 homolog (Chlamydomonas) |
| SCARB2 | scavenger receptor class B, member 2 |
| SERPINB3 | serpin peptidase inhibitor, clade B (ovalbumin), member 3 |
| SLAMF8 | SLAM family member 8 |
| SLC4A8 | solute carrier family 4, sodium bicarbonate cotransporter, member 8 |
| SPDEF | SAM pointed domain containing ETS transcription factor |
| STAT4 | signal transducer and activator of transcription 4 |
| TAPBP | TAP binding protein (tapasin) |
| TAPBPL | TAP binding protein-like |
| TBC1D2 | TBC1 domain family, member 2 |
| TBCD | tubulin folding cofactor D |
| TBX6 | T-box 6 |
| TCF20 | transcription factor 20 (AR1) |
| TFAP2C | transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma) |
| TK2 | thymidine kinase 2, mitochondrial |
| TNK1 | tyrosine kinase, non-receptor, 1 |
| TRAF4 | TNF receptor-associated factor 4 |
| USP12 | ubiquitin specific peptidase 12 |
| UTY | ubiquitously transcribed tetratricopeptide repeat containing, Y-linked |
| VIPR2 | vasoactive intestinal peptide receptor 2 |
| WISP1 | WNT1 inducible signaling pathway protein 1 |
| ZNF205 | zinc finger protein 205 |
| ZNF484 | zinc finger protein 484 |
| ZNF862 | zinc finger protein 862 |
| Symbol | Name |
|---|---|
| ABCA11P | ATP-binding cassette, sub-family A (ABC1), member 11, pseudogene |
| ACYP1 | acylphosphatase 1, erythrocyte (common) type |
| ANAPC2 | anaphase promoting complex subunit 2 |
| ANKS1A | ankyrin repeat and sterile alpha motif domain containing 1A |
| ANO10 | anoctamin 10 |
| AP4M1 | adaptor-related protein complex 4, mu 1 subunit |
| APPL2 | adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2 |
| BBS7 | Bardet-Biedl syndrome 7 |
| BPGM | 2,3-bisphosphoglycerate mutase |
| C12ORF49 | chromosome 12 open reading frame 49 |
| CASD1 | CAS1 domain containing 1 |
| CCNJ | cyclin J |
| CDK3 | cyclin-dependent kinase 3 |
| CDKN2D | cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4) |
| CHRNA5 | cholinergic receptor, nicotinic, alpha 5 (neuronal) |
| CISH | cytokine inducible SH2-containing protein |
| CREB3 | cAMP responsive element binding protein 3 |
| CRNKL1 | crooked neck pre-mRNA splicing factor 1 |
| CRYZ | crystallin, zeta (quinone reductase) |
| DDHD2 | DDHD domain containing 2 |
| DDX31 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 31 |
| DIXDC1 | DIX domain containing 1 |
| DNA2 | DNA replication helicase/nuclease 2 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 |
| DOLK | dolichol kinase |
| DTWD1 | DTW domain containing 1 |
| E2F6 | E2F transcription factor 6 |
| EMD | emerin |
| EPHX1 | epoxide hydrolase 1, microsomal (xenobiotic) |
| ERMAP | erythroblast membrane-associated protein (Scianna blood group) |
| FANCF | Fanconi anemia, complementation group F |
| FKBP14 | FK506 binding protein 14, 22 kDa |
| GALNT12 | polypeptide N-acetylgalactosaminyltransferase 12 |
| GK3P | glycerol kinase 3 pseudogene |
| GPR85 | G protein-coupled receptor 85 |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| HIST1H2BN | histone cluster 1, H2bn |
| HMGB3 | high mobility group box 3 |
| HS1BP3 | HCLS1 binding protein 3 |
| HSPBP1 | HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1 |
| ICAM3 | intercellular adhesion molecule 3 |
| IFI6 | interferon, alpha-inducible protein 6 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 |
| IMPDH1 | IMP (inosine 5'-monophosphate) dehydrogenase 1 |
| INPP1 | inositol polyphosphate-1-phosphatase |
| KIAA0753 | KIAA0753 |
| KLF10 | Kruppel-like factor 10 |
| LINC00597 | long intergenic non-protein coding RNA 597 |
| LOC157562 | uncharacterized LOC157562 |
| LTB4R | leukotriene B4 receptor |
| MAFB | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B |
| MMACHC | methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria |
| MPDU1 | mannose-P-dolichol utilization defect 1 |
| MYD88 | myeloid differentiation primary response 88 |
| NFS1 | NFS1 cysteine desulfurase |
| NPIPB3 | nuclear pore complex interacting protein family, member B3 |
| NR1H3 | nuclear receptor subfamily 1, group H, member 3 |
| NT5C | 5', 3'-nucleotidase, cytosolic |
| ODF2 | outer dense fiber of sperm tails 2 |
| PDPR | pyruvate dehydrogenase phosphatase regulatory subunit |
| PECR | peroxisomal trans-2-enoyl-CoA reductase |
| PMCH | pro-melanin-concentrating hormone |
| PPARG | peroxisome proliferator-activated receptor gamma |
| PRRG1 | proline rich Gla (G-carboxyglutamic acid) 1 |
| PTGES2 | prostaglandin E synthase 2 |
| RBM7 | RNA binding motif protein 7 |
| RINT1 | RAD50 interactor 1 |
| RPAIN | RPA interacting protein |
| RPIA | ribose 5-phosphate isomerase A |
| RUFY2 | RUN and FYVE domain containing 2 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 |
| SGTA | small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha |
| SLC16A4 | solute carrier family 16, member 4 |
| SLC31A1 | solute carrier family 31 (copper transporter), member 1 |
| SOAT1 | sterol O-acyltransferase 1 |
| SPAG1 | sperm associated antigen 1 |
| SYF2 | SYF2 pre-mRNA-splicing factor |
| TAF6 | TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa |
| TCFL5 | transcription factor-like 5 (basic helix-loop-helix) |
| THOP1 | thimet oligopeptidase 1 |
| TIGAR | TP53 induced glycolysis regulatory phosphatase |
| TRAPPC11 | trafficking protein particle complex 11 |
| TTC26 | tetratricopeptide repeat domain 26 |
| UBE2S | ubiquitin-conjugating enzyme E2S |
| UNC93B1 | unc-93 homolog B1 (C. elegans) |
| VCPKMT | valosin containing protein lysine (K) methyltransferase |
| VPS39 | vacuolar protein sorting 39 homolog (S. cerevisiae) |
| VPS8 | vacuolar protein sorting 8 homolog (S. cerevisiae) |
| YEATS4 | YEATS domain containing 4 |
| ZCCHC2 | zinc finger, CCHC domain containing 2 |
| ZNF10 | zinc finger protein 10 |
| ZNF215 | zinc finger protein 215 |
| ZNF250 | zinc finger protein 250 |
| ZNF354A | zinc finger protein 354A |
| ZNF529 | zinc finger protein 529 |
| ZNF573 | zinc finger protein 573 |
| ZNF667 | zinc finger protein 667 |