| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the sotalol-4079 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 |
| ACOX1 | acyl-CoA oxidase 1, palmitoyl |
| ACTA1 | actin, alpha 1, skeletal muscle |
| AIM1L | absent in melanoma 1-like |
| AOAH | acyloxyacyl hydrolase (neutrophil) |
| APP | amyloid beta (A4) precursor protein |
| ARHGAP26 | Rho GTPase activating protein 26 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) |
| ATP11A | ATPase, class VI, type 11A |
| ATP8A2 | ATPase, aminophospholipid transporter, class I, type 8A, member 2 |
| BRINP2 | bone morphogenetic protein/retinoic acid inducible neural-specific 2 |
| C11ORF1 | chromosome 11 open reading frame 1 |
| CAMK4 | calcium/calmodulin-dependent protein kinase IV |
| CATSPERG | catsper channel auxiliary subunit gamma |
| CD101 | CD101 molecule |
| CFAP74 | cilia and flagella associated protein 74 |
| CLSTN3 | calsyntenin 3 |
| COMT | catechol-O-methyltransferase |
| CSF1R | colony stimulating factor 1 receptor |
| CSRP3 | cysteine and glycine-rich protein 3 (cardiac LIM protein) |
| DCAF11 | DDB1 and CUL4 associated factor 11 |
| DTNA | dystrobrevin, alpha |
| DTNB | dystrobrevin, beta |
| EDN2 | endothelin 2 |
| ELSPBP1 | epididymal sperm binding protein 1 |
| EPHA3 | EPH receptor A3 |
| FCAR | Fc fragment of IgA receptor |
| FGF4 | fibroblast growth factor 4 |
| FGL2 | fibrinogen-like 2 |
| FLT4 | fms-related tyrosine kinase 4 |
| FRMD4B | FERM domain containing 4B |
| G3BP1 | GTPase activating protein (SH3 domain) binding protein 1 |
| GNG4 | guanine nucleotide binding protein (G protein), gamma 4 |
| GPLD1 | glycosylphosphatidylinositol specific phospholipase D1 |
| GPR37L1 | G protein-coupled receptor 37 like 1 |
| HIST1H2BL | histone cluster 1, H2bl |
| HOXD1 | homeobox D1 |
| HOXD13 | homeobox D13 |
| HTR7 | 5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled |
| IDI2-AS1 | IDI2 antisense RNA 1 |
| IFNA8 | interferon, alpha 8 |
| IL12RB1 | interleukin 12 receptor, beta 1 |
| IL32 | interleukin 32 |
| IL33R | interleukin 33 receptor |
| IRX4 | iroquois homeobox 4 |
| ITGB4 | integrin, beta 4 |
| KCNJ13 | potassium channel, inwardly rectifying subfamily J, member 13 |
| KCNJ3 | potassium channel, inwardly rectifying subfamily J, member 3 |
| KCNK12 | potassium channel, two pore domain subfamily K, member 12 |
| KHK | ketohexokinase (fructokinase) |
| LINC00652 | long intergenic non-protein coding RNA 652 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 |
| MAN2A2 | mannosidase, alpha, class 2A, member 2 |
| MAU2 | MAU2 sister chromatid cohesion factor |
| MMRN1 | multimerin 1 |
| MPL | MPL proto-oncogene, thrombopoietin receptor |
| MYCL | v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog |
| MYO1B | myosin IB |
| N4BP2L2-IT2 | N4BPL2 intronic transcript 2 |
| NCR1 | natural cytotoxicity triggering receptor 1 |
| NF1 | neurofibromin 1 |
| NTNG1 | netrin G1 |
| OGFR | opioid growth factor receptor |
| PCYT1A | phosphate cytidylyltransferase 1, choline, alpha |
| PDE12 | phosphodiesterase 12 |
| PDE4D | phosphodiesterase 4D, cAMP-specific |
| PHEX | phosphate regulating endopeptidase homolog, X-linked |
| PHF2 | PHD finger protein 2 |
| PLA2G3 | phospholipase A2, group III |
| PLCE1 | phospholipase C, epsilon 1 |
| PML | promyelocytic leukemia |
| PPP1R1A | protein phosphatase 1, regulatory (inhibitor) subunit 1A |
| PRKCQ | protein kinase C, theta |
| PRR5 | proline rich 5 (renal) |
| PSG4 | pregnancy specific beta-1-glycoprotein 4 |
| PTGDR2 | prostaglandin D2 receptor 2 |
| PTGDS | prostaglandin D2 synthase 21kDa (brain) |
| PURA | purine-rich element binding protein A |
| RGS12 | regulator of G-protein signaling 12 |
| RIMS2 | regulating synaptic membrane exocytosis 2 |
| RIN3 | Ras and Rab interactor 3 |
| RNF122 | ring finger protein 122 |
| RNF126P1 | ring finger protein 126 pseudogene 1 |
| SCN10A | sodium channel, voltage gated, type X alpha subunit |
| SP110 | SP110 nuclear body protein |
| STOML1 | stomatin (EPB72)-like 1 |
| SYK | spleen tyrosine kinase |
| TBX2 | T-box 2 |
| TDRD1 | tudor domain containing 1 |
| TFAP2B | transcription factor AP-2 beta (activating enhancer binding protein 2 beta) |
| TGFBR1 | transforming growth factor, beta receptor 1 |
| TMEM206 | transmembrane protein 206 |
| TNFRSF4 | tumor necrosis factor receptor superfamily, member 4 |
| TNIK | TRAF2 and NCK interacting kinase |
| TRPC2 | transient receptor potential cation channel, subfamily C, member 2, pseudogene |
| VGLL3 | vestigial-like family member 3 |
| VPS16 | vacuolar protein sorting 16 homolog (S. cerevisiae) |
| ZNF345 | zinc finger protein 345 |
| Symbol | Name |
|---|---|
| ADAM23 | ADAM metallopeptidase domain 23 |
| AKR1B10 | aldo-keto reductase family 1, member B10 (aldose reductase) |
| ALPK1 | alpha-kinase 1 |
| ARHGAP10 | Rho GTPase activating protein 10 |
| ASB7 | ankyrin repeat and SOCS box containing 7 |
| ATP8B2 | ATPase, aminophospholipid transporter, class I, type 8B, member 2 |
| ATPAF2 | ATP synthase mitochondrial F1 complex assembly factor 2 |
| BAGE | B melanoma antigen |
| BMP10 | bone morphogenetic protein 10 |
| BSPRY | B-box and SPRY domain containing |
| BTF3P11 | basic transcription factor 3 pseudogene 11 |
| C19ORF54 | chromosome 19 open reading frame 54 |
| CCDC132 | coiled-coil domain containing 132 |
| CCT6B | chaperonin containing TCP1, subunit 6B (zeta 2) |
| CD68 | CD68 molecule |
| CFAP69 | cilia and flagella associated protein 69 |
| CNN1 | calponin 1, basic, smooth muscle |
| CRISPLD2 | cysteine-rich secretory protein LCCL domain containing 2 |
| CTC1 | CTS telomere maintenance complex component 1 |
| DAGLA | diacylglycerol lipase, alpha |
| DLK2 | delta-like 2 homolog (Drosophila) |
| ELP6 | elongator acetyltransferase complex subunit 6 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 |
| EXOC6B | exocyst complex component 6B |
| FBXO22 | F-box protein 22 |
| FBXO31 | F-box protein 31 |
| GLS2 | glutaminase 2 (liver, mitochondrial) |
| GMPR | guanosine monophosphate reductase |
| GPC3 | glypican 3 |
| GRTP1 | growth hormone regulated TBC protein 1 |
| HOXA4 | homeobox A4 |
| HSPA1L | heat shock 70kDa protein 1-like |
| IBA57 | IBA57, iron-sulfur cluster assembly homolog (S. cerevisiae) |
| ICK | intestinal cell (MAK-like) kinase |
| IFI6 | interferon, alpha-inducible protein 6 |
| IFT140 | intraflagellar transport 140 |
| IRF2BP1 | interferon regulatory factor 2 binding protein 1 |
| KANSL1L | KAT8 regulatory NSL complex subunit 1-like |
| KCNS1 | potassium voltage-gated channel, modifier subfamily S, member 1 |
| KIAA1462 | KIAA1462 |
| KLF1 | Kruppel-like factor 1 (erythroid) |
| LHPP | phospholysine phosphohistidine inorganic pyrophosphate phosphatase |
| LIME1 | Lck interacting transmembrane adaptor 1 |
| LMO2 | LIM domain only 2 (rhombotin-like 1) |
| LOC202181 | SUMO-interacting motifs containing 1 pseudogene |
| LPAR4 | lysophosphatidic acid receptor 4 |
| LUM | lumican |
| MDFI | MyoD family inhibitor |
| MMP2 | matrix metallopeptidase 2 |
| MTCP1 | mature T-cell proliferation 1 |
| MYLK | myosin light chain kinase |
| NAT6 | N-acetyltransferase 6 (GCN5-related) |
| NDE1 | nudE neurodevelopment protein 1 |
| NINJ1 | ninjurin 1 |
| NPDC1 | neural proliferation, differentiation and control, 1 |
| NT5M | 5',3'-nucleotidase, mitochondrial |
| OR12D2 | olfactory receptor, family 12, subfamily D, member 2 (gene/pseudogene) |
| OSBP2 | oxysterol binding protein 2 |
| OXCT2 | 3-oxoacid CoA transferase 2 |
| P2RY1 | purinergic receptor P2Y, G-protein coupled, 1 |
| PARP3 | poly (ADP-ribose) polymerase family, member 3 |
| PCDHA5 | protocadherin alpha 5 |
| PDK4 | pyruvate dehydrogenase kinase, isozyme 4 |
| PITPNM1 | phosphatidylinositol transfer protein, membrane-associated 1 |
| PLXNB3 | plexin B3 |
| POM121 | POM121 transmembrane nucleoporin |
| PPL | periplakin |
| PRSS22 | protease, serine, 22 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) |
| RBFOX1 | RNA binding protein, fox-1 homolog (C. elegans) 1 |
| RIBC2 | RIB43A domain with coiled-coils 2 |
| RPAP1 | RNA polymerase II associated protein 1 |
| RPH3AL | rabphilin 3A-like (without C2 domains) |
| RPL23AP32 | ribosomal protein L23a pseudogene 32 |
| S1PR1 | sphingosine-1-phosphate receptor 1 |
| SCARA3 | scavenger receptor class A, member 3 |
| SCUBE3 | signal peptide, CUB domain, EGF-like 3 |
| SLC12A9 | solute carrier family 12, member 9 |
| SLC18A2 | solute carrier family 18 (vesicular monoamine transporter), member 2 |
| SLC22A18 | solute carrier family 22, member 18 |
| SPATA2L | spermatogenesis associated 2-like |
| STAG3L4 | stromal antigen 3-like 4 (pseudogene) |
| SYT17 | synaptotagmin XVII |
| SYTL2 | synaptotagmin-like 2 |
| TAF4B | TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa |
| TAGLN3 | transgelin 3 |
| THSD4 | thrombospondin, type I, domain containing 4 |
| TMEM120B | transmembrane protein 120B |
| TMEM209 | transmembrane protein 209 |
| TNFRSF14 | tumor necrosis factor receptor superfamily, member 14 |
| WDR25 | WD repeat domain 25 |
| WNT10B | wingless-type MMTV integration site family, member 10B |
| YY2 | YY2 transcription factor |
| ZNF230 | zinc finger protein 230 |
| ZNF268 | zinc finger protein 268 |
| ZNF675 | zinc finger protein 675 |
| ZNF768 | zinc finger protein 768 |
| ZNF816 | zinc finger protein 816 |
| ZSCAN2 | zinc finger and SCAN domain containing 2 |
