| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the sotalol-4160 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADAM22 | ADAM metallopeptidase domain 22 |
| ADGRE3 | adhesion G protein-coupled receptor E3 |
| APBA2 | amyloid beta (A4) precursor protein-binding, family A, member 2 |
| AQP3 | aquaporin 3 (Gill blood group) |
| ARHGAP28 | Rho GTPase activating protein 28 |
| ARHGEF4 | Rho guanine nucleotide exchange factor (GEF) 4 |
| ATP2B2 | ATPase, Ca++ transporting, plasma membrane 2 |
| BRF1 | BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit |
| CASP4 | caspase 4, apoptosis-related cysteine peptidase |
| CCR5 | chemokine (C-C motif) receptor 5 (gene/pseudogene) |
| CD1C | CD1c molecule |
| CD1E | CD1e molecule |
| CDH2 | cadherin 2, type 1, N-cadherin (neuronal) |
| CDK6 | cyclin-dependent kinase 6 |
| CFAP69 | cilia and flagella associated protein 69 |
| CFDP1 | craniofacial development protein 1 |
| CIB2 | calcium and integrin binding family member 2 |
| CNKSR2 | connector enhancer of kinase suppressor of Ras 2 |
| CNTNAP2 | contactin associated protein-like 2 |
| COL3A1 | collagen, type III, alpha 1 |
| COL5A2 | collagen, type V, alpha 2 |
| CORO2B | coronin, actin binding protein, 2B |
| CRHR1 | corticotropin releasing hormone receptor 1 |
| CST8 | cystatin 8 (cystatin-related epididymal specific) |
| DMPK | dystrophia myotonica-protein kinase |
| DNAH7 | dynein, axonemal, heavy chain 7 |
| EPS8L3 | EPS8-like 3 |
| FABP3 | fatty acid binding protein 3, muscle and heart |
| FUT4 | fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific) |
| GABBR2 | gamma-aminobutyric acid (GABA) B receptor, 2 |
| GIF | gastric intrinsic factor (vitamin B synthesis) |
| GPR22 | G protein-coupled receptor 22 |
| GRIK5 | glutamate receptor, ionotropic, kainate 5 |
| GRIP2 | glutamate receptor interacting protein 2 |
| GTPBP1 | GTP binding protein 1 |
| HAB1 | B1 for mucin |
| HDAC9 | histone deacetylase 9 |
| HIST1H1B | histone cluster 1, H1b |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like |
| HS3ST1 | heparan sulfate (glucosamine) 3-O-sulfotransferase 1 |
| HSD17B3 | hydroxysteroid (17-beta) dehydrogenase 3 |
| IFNA14 | interferon, alpha 14 |
| IL12RB2 | interleukin 12 receptor, beta 2 |
| IRF4 | interferon regulatory factor 4 |
| KCNS1 | potassium voltage-gated channel, modifier subfamily S, member 1 |
| KIR2DS1 | killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 1 |
| KLF1 | Kruppel-like factor 1 (erythroid) |
| KRT24 | keratin 24, type I |
| KRT33A | keratin 33A, type I |
| KSR1 | kinase suppressor of ras 1 |
| LINC00341 | long intergenic non-protein coding RNA 341 |
| LPL | lipoprotein lipase |
| LRRC37BP1 | leucine rich repeat containing 37B pseudogene 1 |
| LYL1 | lymphoblastic leukemia associated hematopoiesis regulator 1 |
| MAGEC3 | melanoma antigen family C3 |
| MAP2K7 | mitogen-activated protein kinase kinase 7 |
| MAPK8IP3 | mitogen-activated protein kinase 8 interacting protein 3 |
| MGEA5 | meningioma expressed antigen 5 (hyaluronidase) |
| MIER2 | mesoderm induction early response 1, family member 2 |
| MMP25 | matrix metallopeptidase 25 |
| MR1 | major histocompatibility complex, class I-related |
| MS4A1 | membrane-spanning 4-domains, subfamily A, member 1 |
| MYH14 | myosin, heavy chain 14, non-muscle |
| MYL4 | myosin, light chain 4, alkali; atrial, embryonic |
| MYOZ3 | myozenin 3 |
| NANOG | Nanog homeobox |
| OMD | osteomodulin |
| PAPOLG | poly(A) polymerase gamma |
| PDE10A | phosphodiesterase 10A |
| PKNOX2 | PBX/knotted 1 homeobox 2 |
| PODNL1 | podocan-like 1 |
| POFUT1 | protein O-fucosyltransferase 1 |
| POU1F1 | POU class 1 homeobox 1 |
| PTCH1 | patched 1 |
| PTCRA | pre T-cell antigen receptor alpha |
| RAB40A | RAB40A, member RAS oncogene family |
| RABGAP1 | RAB GTPase activating protein 1 |
| RAMP2 | receptor (G protein-coupled) activity modifying protein 2 |
| RGS4 | regulator of G-protein signaling 4 |
| RPL35A | ribosomal protein L35a |
| RUNDC3A | RUN domain containing 3A |
| RUNX1T1 | runt-related transcription factor 1; translocated to, 1 (cyclin D-related) |
| SH2D3A | SH2 domain containing 3A |
| SIGLEC8 | sialic acid binding Ig-like lectin 8 |
| SIPA1 | signal-induced proliferation-associated 1 |
| SLC35G2 | solute carrier family 35, member G2 |
| STXBP5L | syntaxin binding protein 5-like |
| TBR1 | T-box, brain, 1 |
| TDRD12 | tudor domain containing 12 |
| TMPRSS11D | transmembrane protease, serine 11D |
| TNS2 | tensin 2 |
| TPM3 | tropomyosin 3 |
| TRGV5 | T cell receptor gamma variable 5 |
| TTC9 | tetratricopeptide repeat domain 9 |
| USP22 | ubiquitin specific peptidase 22 |
| WSCD1 | WSC domain containing 1 |
| ZBED4 | zinc finger, BED-type containing 4 |
| ZER1 | zyg-11 related, cell cycle regulator |
| ZMIZ2 | zinc finger, MIZ-type containing 2 |
| Symbol | Name |
|---|---|
| ACTG2 | actin, gamma 2, smooth muscle, enteric |
| ADAP2 | ArfGAP with dual PH domains 2 |
| AHNAK2 | AHNAK nucleoprotein 2 |
| ALOX12P2 | arachidonate 12-lipoxygenase pseudogene 2 |
| ALS2CL | ALS2 C-terminal like |
| AP1S1 | adaptor-related protein complex 1, sigma 1 subunit |
| ARHGDIB | Rho GDP dissociation inhibitor (GDI) beta |
| ASIC3 | acid sensing (proton gated) ion channel 3 |
| ATP6V1B1 | ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B1 |
| CAMK1 | calcium/calmodulin-dependent protein kinase I |
| CCBL1 | cysteine conjugate-beta lyase, cytoplasmic |
| CCDC85C | coiled-coil domain containing 85C |
| CCRN4L | CCR4 carbon catabolite repression 4-like (S. cerevisiae) |
| CD3D | CD3d molecule, delta (CD3-TCR complex) |
| CEP170B | centrosomal protein 170B |
| CRY2 | cryptochrome circadian clock 2 |
| DBR1 | debranching RNA lariats 1 |
| DDIT3 | DNA-damage-inducible transcript 3 |
| DNAJA4 | DnaJ (Hsp40) homolog, subfamily A, member 4 |
| EPX | eosinophil peroxidase |
| ETNK2 | ethanolamine kinase 2 |
| FAAH | fatty acid amide hydrolase |
| FAM186A | family with sequence similarity 186, member A |
| FBXO4 | F-box protein 4 |
| FGF23 | fibroblast growth factor 23 |
| FLJ22184 | |
| GFI1 | growth factor independent 1 transcription repressor |
| GNG4 | guanine nucleotide binding protein (G protein), gamma 4 |
| GPR27 | G protein-coupled receptor 27 |
| GRAMD1C | GRAM domain containing 1C |
| HDAC11 | histone deacetylase 11 |
| HIST1H2AI | histone cluster 1, H2ai |
| HIST1H3E | histone cluster 1, H3e |
| HOXA4 | homeobox A4 |
| HOXC5 | homeobox C5 |
| IGSF1 | immunoglobulin superfamily, member 1 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) |
| ITIH2 | inter-alpha-trypsin inhibitor heavy chain 2 |
| KHDRBS3 | KH domain containing, RNA binding, signal transduction associated 3 |
| KIAA1024 | KIAA1024 |
| KLF3 | Kruppel-like factor 3 (basic) |
| LAMA3 | laminin, alpha 3 |
| LY6G6C | lymphocyte antigen 6 complex, locus G6C |
| MADCAM1 | mucosal vascular addressin cell adhesion molecule 1 |
| MED9 | mediator complex subunit 9 |
| MMP2 | matrix metallopeptidase 2 |
| MOB3B | MOB kinase activator 3B |
| MTCP1 | mature T-cell proliferation 1 |
| MVP | major vault protein |
| NACA2 | nascent polypeptide-associated complex alpha subunit 2 |
| NAT6 | N-acetyltransferase 6 (GCN5-related) |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) |
| NSUN6 | NOP2/Sun domain family, member 6 |
| NXPE3 | neurexophilin and PC-esterase domain family, member 3 |
| OLFML2A | olfactomedin-like 2A |
| OR2B6 | olfactory receptor, family 2, subfamily B, member 6 |
| PARG | poly (ADP-ribose) glycohydrolase |
| PDE8B | phosphodiesterase 8B |
| PLCD1 | phospholipase C, delta 1 |
| PLEKHA6 | pleckstrin homology domain containing, family A member 6 |
| POLM | polymerase (DNA directed), mu |
| POMT2 | protein-O-mannosyltransferase 2 |
| POPDC3 | popeye domain containing 3 |
| PSG4 | pregnancy specific beta-1-glycoprotein 4 |
| QPCTL | glutaminyl-peptide cyclotransferase-like |
| RASL11B | RAS-like, family 11, member B |
| RCBTB2 | regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2 |
| RHPN1-AS1 | RHPN1 antisense RNA 1 (head to head) |
| RNF126P1 | ring finger protein 126 pseudogene 1 |
| RNPEPL1 | arginyl aminopeptidase (aminopeptidase B)-like 1 |
| RUNDC3B | RUN domain containing 3B |
| SCN10A | sodium channel, voltage gated, type X alpha subunit |
| SEMA7A | semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group) |
| SETD1A | SET domain containing 1A |
| SLC34A2 | solute carrier family 34 (type II sodium/phosphate cotransporter), member 2 |
| SLC3A1 | solute carrier family 3 (amino acid transporter heavy chain), member 1 |
| SLC9A5 | solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5 |
| SLIT2 | slit homolog 2 (Drosophila) |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase |
| SMPD2 | sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase) |
| SNCAIP | synuclein, alpha interacting protein |
| STARD3 | StAR-related lipid transfer (START) domain containing 3 |
| TBC1D19 | TBC1 domain family, member 19 |
| THRAP3 | thyroid hormone receptor associated protein 3 |
| TMCC2 | transmembrane and coiled-coil domain family 2 |
| TMEM53 | transmembrane protein 53 |
| TOR4A | torsin family 4, member A |
| TRIM68 | tripartite motif containing 68 |
| TRPM2 | transient receptor potential cation channel, subfamily M, member 2 |
| TUBA3C | tubulin, alpha 3c |
| TYRP1 | tyrosinase-related protein 1 |
| UBE2NL | ubiquitin-conjugating enzyme E2N-like (gene/pseudogene) |
| UPK2 | uroplakin 2 |
| WDR76 | WD repeat domain 76 |
| WDR78 | WD repeat domain 78 |
| XDH | xanthine dehydrogenase |
| ZBTB48 | zinc finger and BTB domain containing 48 |
| ZNF506 | zinc finger protein 506 |
