| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the sotalol-7338 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACTR3B | ARP3 actin-related protein 3 homolog B (yeast) |
| ADAP1 | ArfGAP with dual PH domains 1 |
| ADRBK2 | adrenergic, beta, receptor kinase 2 |
| AMFR | autocrine motility factor receptor, E3 ubiquitin protein ligase |
| ANKRD2 | ankyrin repeat domain 2 (stretch responsive muscle) |
| ATAT1 | alpha tubulin acetyltransferase 1 |
| ATF7IP | activating transcription factor 7 interacting protein |
| ATXN2L | ataxin 2-like |
| BMP5 | bone morphogenetic protein 5 |
| C14ORF79 | chromosome 14 open reading frame 79 |
| CAMK2G | calcium/calmodulin-dependent protein kinase II gamma |
| CBL | Cbl proto-oncogene, E3 ubiquitin protein ligase |
| CCDC132 | coiled-coil domain containing 132 |
| CEP72 | centrosomal protein 72kDa |
| CFAP44 | cilia and flagella associated protein 44 |
| CFLAR | CASP8 and FADD-like apoptosis regulator |
| COL5A1 | collagen, type V, alpha 1 |
| COX5B | cytochrome c oxidase subunit Vb |
| CTNS | cystinosin, lysosomal cystine transporter |
| DEPDC5 | DEP domain containing 5 |
| DST | dystonin |
| DVL2 | dishevelled segment polarity protein 2 |
| DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 |
| FAM105A | family with sequence similarity 105, member A |
| FAM120C | family with sequence similarity 120C |
| FCF1 | FCF1 rRNA-processing protein |
| FGD1 | FYVE, RhoGEF and PH domain containing 1 |
| FLCN | folliculin |
| FNDC3A | fibronectin type III domain containing 3A |
| FXR2 | fragile X mental retardation, autosomal homolog 2 |
| FZD7 | frizzled class receptor 7 |
| GMEB1 | glucocorticoid modulatory element binding protein 1 |
| GOLGA2 | golgin A2 |
| GPR157 | G protein-coupled receptor 157 |
| GRIK5 | glutamate receptor, ionotropic, kainate 5 |
| HMGN5 | high mobility group nucleosome binding domain 5 |
| HPS4 | Hermansky-Pudlak syndrome 4 |
| HSPA1L | heat shock 70kDa protein 1-like |
| IFNA14 | interferon, alpha 14 |
| ITGB4 | integrin, beta 4 |
| KDM5A | lysine (K)-specific demethylase 5A |
| KIF1A | kinesin family member 1A |
| LGALS4 | lectin, galactoside-binding, soluble, 4 |
| LONRF3 | LON peptidase N-terminal domain and ring finger 3 |
| MMP16 | matrix metallopeptidase 16 (membrane-inserted) |
| N4BP2L2 | NEDD4 binding protein 2-like 2 |
| NEUROD4 | neuronal differentiation 4 |
| NF1 | neurofibromin 1 |
| NR2E3 | nuclear receptor subfamily 2, group E, member 3 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 |
| PCNXL4 | pecanex-like 4 (Drosophila) |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 |
| POFUT1 | protein O-fucosyltransferase 1 |
| POPDC3 | popeye domain containing 3 |
| PPAP2B | phosphatidic acid phosphatase type 2B |
| PVR | poliovirus receptor |
| R3HDM1 | R3H domain containing 1 |
| RAD23B | RAD23 homolog B (S. cerevisiae) |
| RASA3 | RAS p21 protein activator 3 |
| RBM19 | RNA binding motif protein 19 |
| S100A8 | S100 calcium binding protein A8 |
| SBF1 | SET binding factor 1 |
| SEC24D | SEC24 family member D |
| SFI1 | Sfi1 homolog, spindle assembly associated (yeast) |
| SLC16A10 | solute carrier family 16 (aromatic amino acid transporter), member 10 |
| SLC35D1 | solute carrier family 35 (UDP-GlcA/UDP-GalNAc transporter), member D1 |
| SLMO1 | slowmo homolog 1 (Drosophila) |
| SMAD1 | SMAD family member 1 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) |
| SSPN | sarcospan |
| ST5 | suppression of tumorigenicity 5 |
| STAM2 | signal transducing adaptor molecule (SH3 domain and ITAM motif) 2 |
| TADA3 | transcriptional adaptor 3 |
| TAF6L | TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa |
| TAOK2 | TAO kinase 2 |
| TAPBP | TAP binding protein (tapasin) |
| THBD | thrombomodulin |
| TIMELESS | timeless circadian clock |
| TNK1 | tyrosine kinase, non-receptor, 1 |
| TOP3A | topoisomerase (DNA) III alpha |
| TRIM3 | tripartite motif containing 3 |
| TRPC1 | transient receptor potential cation channel, subfamily C, member 1 |
| TTBK2 | tau tubulin kinase 2 |
| UBE2I | ubiquitin-conjugating enzyme E2I |
| UBE3A | ubiquitin protein ligase E3A |
| UBXN1 | UBX domain protein 1 |
| UPK3A | uroplakin 3A |
| USP24 | ubiquitin specific peptidase 24 |
| UTRN | utrophin |
| VDAC3 | voltage-dependent anion channel 3 |
| VPS13A | vacuolar protein sorting 13 homolog A (S. cerevisiae) |
| ZMIZ2 | zinc finger, MIZ-type containing 2 |
| ZNF34 | zinc finger protein 34 |
| ZNF492 | zinc finger protein 492 |
| ZNF668 | zinc finger protein 668 |
| ZNF821 | zinc finger protein 821 |
| ZNRD1-AS1 | ZNRD1 antisense RNA 1 |
| ZZEF1 | zinc finger, ZZ-type with EF-hand domain 1 |
| Symbol | Name |
|---|---|
| ADCY7 | adenylate cyclase 7 |
| AFAP1 | actin filament associated protein 1 |
| AHDC1 | AT hook, DNA binding motif, containing 1 |
| ANO10 | anoctamin 10 |
| ARMC6 | armadillo repeat containing 6 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) |
| C11ORF30 | chromosome 11 open reading frame 30 |
| C11ORF80 | chromosome 11 open reading frame 80 |
| C1ORF106 | chromosome 1 open reading frame 106 |
| C1ORF35 | chromosome 1 open reading frame 35 |
| CA11 | carbonic anhydrase XI |
| CBX7 | chromobox homolog 7 |
| CCZ1B | CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae) |
| CENPQ | centromere protein Q |
| CHML | choroideremia-like (Rab escort protein 2) |
| CIDEC | cell death-inducing DFFA-like effector c |
| CLCF1 | cardiotrophin-like cytokine factor 1 |
| CLDN15 | claudin 15 |
| CLSTN2 | calsyntenin 2 |
| CNGB3 | cyclic nucleotide gated channel beta 3 |
| CPSF3L | cleavage and polyadenylation specific factor 3-like |
| CRYBB2P1 | crystallin, beta B2 pseudogene 1 |
| CTNNBIP1 | catenin, beta interacting protein 1 |
| DAPP1 | dual adaptor of phosphotyrosine and 3-phosphoinositides |
| DNALI1 | dynein, axonemal, light intermediate chain 1 |
| DYNC2H1 | dynein, cytoplasmic 2, heavy chain 1 |
| DYSF | dysferlin |
| EFHD2 | EF-hand domain family, member D2 |
| ESRP2 | epithelial splicing regulatory protein 2 |
| EXD3 | exonuclease 3'-5' domain containing 3 |
| F3 | coagulation factor III (thromboplastin, tissue factor) |
| FAM50B | family with sequence similarity 50, member B |
| FLJ22184 | |
| FRS2 | fibroblast growth factor receptor substrate 2 |
| FXN | frataxin |
| GBP2 | guanylate binding protein 2, interferon-inducible |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 |
| GPC3 | glypican 3 |
| GPX2 | glutathione peroxidase 2 |
| GRB7 | growth factor receptor-bound protein 7 |
| GSTCD | glutathione S-transferase, C-terminal domain containing |
| GSTT1 | glutathione S-transferase theta 1 |
| GYS1 | glycogen synthase 1 (muscle) |
| HIST1H3B | histone cluster 1, H3b |
| HIST1H4D | histone cluster 1, H4d |
| HTR1E | 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled |
| IFI6 | interferon, alpha-inducible protein 6 |
| IFNAR1 | interferon (alpha, beta and omega) receptor 1 |
| IFT81 | intraflagellar transport 81 |
| IL17RA | interleukin 17 receptor A |
| IRF2BP1 | interferon regulatory factor 2 binding protein 1 |
| JUNB | jun B proto-oncogene |
| KCNF1 | potassium channel, voltage gated modifier subfamily F, member 1 |
| KDM5C | lysine (K)-specific demethylase 5C |
| KIAA0754 | KIAA0754 |
| KLF3 | Kruppel-like factor 3 (basic) |
| LIN7A | lin-7 homolog A (C. elegans) |
| LINS | lines homolog (Drosophila) |
| LRIG1 | leucine-rich repeats and immunoglobulin-like domains 1 |
| LYPLA2P1 | lysophospholipase II pseudogene 1 |
| LZTS3 | leucine zipper, putative tumor suppressor family member 3 |
| MAPK8 | mitogen-activated protein kinase 8 |
| MAST3 | microtubule associated serine/threonine kinase 3 |
| MATK | megakaryocyte-associated tyrosine kinase |
| MCC | mutated in colorectal cancers |
| MED15 | mediator complex subunit 15 |
| MUL1 | mitochondrial E3 ubiquitin protein ligase 1 |
| NEK11 | NIMA-related kinase 11 |
| NPFFR1 | neuropeptide FF receptor 1 |
| NPY5R | neuropeptide Y receptor Y5 |
| NUP62CL | nucleoporin 62kDa C-terminal like |
| OLFML2A | olfactomedin-like 2A |
| OR7E156P | olfactory receptor, family 7, subfamily E, member 156 pseudogene |
| OXTR | oxytocin receptor |
| PCSK7 | proprotein convertase subtilisin/kexin type 7 |
| PLCXD1 | phosphatidylinositol-specific phospholipase C, X domain containing 1 |
| PLEKHO1 | pleckstrin homology domain containing, family O member 1 |
| RAB3A | RAB3A, member RAS oncogene family |
| RAPGEFL1 | Rap guanine nucleotide exchange factor (GEF)-like 1 |
| S100A4 | S100 calcium binding protein A4 |
| SEMA4D | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D |
| SERTAD3 | SERTA domain containing 3 |
| SETD8 | SET domain containing (lysine methyltransferase) 8 |
| SLC38A10 | solute carrier family 38, member 10 |
| SND1-IT1 | SND1 intronic transcript 1 |
| SPAG4 | sperm associated antigen 4 |
| SPIDR | scaffolding protein involved in DNA repair |
| TAF4B | TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa |
| TAOK1 | TAO kinase 1 |
| TMEM51 | transmembrane protein 51 |
| TMEM53 | transmembrane protein 53 |
| TRIM25 | tripartite motif containing 25 |
| UBE2O | ubiquitin-conjugating enzyme E2O |
| ULBP2 | UL16 binding protein 2 |
| USP5 | ubiquitin specific peptidase 5 (isopeptidase T) |
| VASH1 | vasohibin 1 |
| VIM | vimentin |
| WDR91 | WD repeat domain 91 |
