sotalol Gene Set

Dataset Guide to Pharmacology Chemical Ligands of Receptors
Category physical interactions
Type ligand (chemical)
Description A sulfonamide that is N-phenylmethanesulfonamide in which the phenyl group is sustituted at position 4 by a 1-hydroxy-2-(isopropylamino)ethyl group. It has both beta-adrenoreceptor blocking (Vaughan Williams Class II) and cardiac action potential duration prolongation (Vaughan Williams Class III) antiarrhythmic properties. It is used (usually as the hydrochloride salt) for the management of ventricular and supraventricular arrhythmias. (Chemical Entities of Biological Interest Ontology, CHEBI_63622)
External Link http://www.guidetopharmacology.org/GRAC/LigandDisplayForward?ligandId=7297
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Genes

2 receptors of the sotalol ligand (chemical) from the curated Guide to Pharmacology Chemical Ligands of Receptors dataset.

Symbol Name
ADRB1 adrenoceptor beta 1
ADRB2 adrenoceptor beta 2, surface