sox10 Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description SRY (sex determining region Y)-box 10|This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional activator after forming a protein complex with other proteins. This protein acts as a nucleocytoplasmic shuttle protein and is important for neural crest and peripheral nervous system development. Mutations in this gene are associated with Waardenburg-Shah and Waardenburg-Hirschsprung disease. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 6663)
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Genes

27 genes co-occuring with the biological term sox10 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ASCL1 achaete-scute family bHLH transcription factor 1
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
DHH desert hedgehog
EDN3 endothelin 3
EDNRB endothelin receptor type B
EPAS1 endothelial PAS domain protein 1
GJB1 gap junction protein, beta 1, 32kDa
GNAQ guanine nucleotide binding protein (G protein), q polypeptide
MIA melanoma inhibitory activity
MITF microphthalmia-associated transcription factor
NES nestin
NF2 neurofibromin 2 (merlin)
NKX2-2 NK2 homeobox 2
NMI N-myc (and STAT) interactor
PAX3 paired box 3
PMP22 peripheral myelin protein 22
POMC proopiomelanocortin
POU3F2 POU class 3 homeobox 2
SF3B1 splicing factor 3b, subunit 1, 155kDa
SHH sonic hedgehog
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
SNAI2 snail family zinc finger 2
SOX10 SRY (sex determining region Y)-box 10
SOX9 SRY (sex determining region Y)-box 9
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box)
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
VWA5A von Willebrand factor A domain containing 5A