sox4 Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description SRY (sex determining region Y)-box 4|This intronless gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins, such as syndecan binding protein (syntenin). The protein may function in the apoptosis pathway leading to cell death as well as to tumorigenesis and may mediate downstream effects of parathyroid hormone (PTH) and PTH-related protein (PTHrP) in bone development. The solution structure has been resolved for the HMG-box of a similar mouse protein. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 6659)
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Genes

30 genes co-occuring with the biological term sox4 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
BBC3 BCL2 binding component 3
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CREB1 cAMP responsive element binding protein 1
CSNK2A1 casein kinase 2, alpha 1 polypeptide
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
DICER1 dicer 1, ribonuclease type III
EGFR epidermal growth factor receptor
ERG v-ets avian erythroblastosis virus E26 oncogene homolog
FOSL2 FOS-like antigen 2
GALNT1 polypeptide N-acetylgalactosaminyltransferase 1
GJA1 gap junction protein, alpha 1, 43kDa
HDAC8 histone deacetylase 8
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
JUP junction plakoglobin
MIR129-1 microRNA 129-1
MIR129-2 microRNA 129-2
MIR30A microRNA 30a
NCAM1 neural cell adhesion molecule 1
POU5F1 POU class 5 homeobox 1
SDCBP syndecan binding protein (syntenin)
SOX2 SRY (sex determining region Y)-box 2
SOX4 SRY (sex determining region Y)-box 4
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
SUMO1 small ubiquitin-like modifier 1
TBX3 T-box 3
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box)
TGFBI transforming growth factor, beta-induced, 68kDa
TP53 tumor protein p53
UBE2I ubiquitin-conjugating enzyme E2I