| Dataset | GeneRIF Biological Term Annotations |
| Category | structural or functional annotations |
| Type | biological term |
| Description | SRY (sex determining region Y)-box 8|This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional activator after forming a protein complex with other proteins. This protein may be involved in brain development and function. Haploinsufficiency for this protein may contribute to the mental retardation found in haemoglobin H-related mental retardation (ART-16 syndrome). [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 30812) |
| Similar Terms | |
| Downloads & Tools |
2 genes co-occuring with the biological term sox8 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.
