sox9 Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description SRY (sex determining region Y)-box 9|The protein encoded by this gene recognizes the sequence CCTTGAG along with other members of the HMG-box class DNA-binding proteins. It acts during chondrocyte differentiation and, with steroidogenic factor 1, regulates transcription of the anti-Muellerian hormone (AMH) gene. Deficiencies lead to the skeletal malformation syndrome campomelic dysplasia, frequently with sex reversal. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 6662)
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Genes

107 genes co-occuring with the biological term sox9 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ACAN aggrecan
AMH anti-Mullerian hormone
AR androgen receptor
BEST1 bestrophin 1
BMP2 bone morphogenetic protein 2
CATSPER1 cation channel, sperm associated 1
CDH5 cadherin 5, type 2 (vascular endothelium)
CDX2 caudal type homeobox 2
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
COL27A1 collagen, type XXVII, alpha 1
COL2A1 collagen, type II, alpha 1
CREB1 cAMP responsive element binding protein 1
CREBBP CREB binding protein
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
DHH desert hedgehog
EGFR epidermal growth factor receptor
EP300 E1A binding protein p300
EPAS1 endothelial PAS domain protein 1
ERG v-ets avian erythroblastosis virus E26 oncogene homolog
ETV1 ets variant 1
FGF2 fibroblast growth factor 2 (basic)
FGF23 fibroblast growth factor 23
FGF9 fibroblast growth factor 9
FOXL2 forkhead box L2
FURIN furin (paired basic amino acid cleaving enzyme)
HAPLN1 hyaluronan and proteoglycan link protein 1
HES1 hes family bHLH transcription factor 1
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
IGFBP7 insulin-like growth factor binding protein 7
IL1B interleukin 1, beta
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2
KLF4 Kruppel-like factor 4 (gut)
LRP6 low density lipoprotein receptor-related protein 6
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MAPK14 mitogen-activated protein kinase 14
MED25 mediator complex subunit 25
MIR101-1 microRNA 101-1
MIR124-1 microRNA 124-1
MIR124-2 microRNA 124-2
MIR124-3 microRNA 124-3
MIR1247 microRNA 1247
MIR140 microRNA 140
MIR145 microRNA 145
MIR32 microRNA 32
MIR495 microRNA 495
MIR96 microRNA 96
MITF microphthalmia-associated transcription factor
MKI67 marker of proliferation Ki-67
MMP13 matrix metallopeptidase 13
MMP3 matrix metallopeptidase 3
MUC2 mucin 2, oligomeric mucus/gel-forming
MYOCD myocardin
NES nestin
NF1 neurofibromin 1
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NKX3-1 NK3 homeobox 1
NONO non-POU domain containing, octamer-binding
NOTCH1 notch 1
NR0B1 nuclear receptor subfamily 0, group B, member 1
NR5A1 nuclear receptor subfamily 5, group A, member 1
ONECUT1 one cut homeobox 1
OTX2 orthodenticle homeobox 2
PAX3 paired box 3
POU3F2 POU class 3 homeobox 2
PPARG peroxisome proliferator-activated receptor gamma
PRKCA protein kinase C, alpha
PRKG2 protein kinase, cGMP-dependent, type II
PTEN phosphatase and tensin homolog
PTGDS prostaglandin D2 synthase 21kDa (brain)
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
RALA v-ral simian leukemia viral oncogene homolog A (ras related)
RARA retinoic acid receptor, alpha
RARB retinoic acid receptor, beta
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
ROCK1 Rho-associated, coiled-coil containing protein kinase 1
RUNX2 runt-related transcription factor 2
SATB2 SATB homeobox 2
SDC4 syndecan 4
SHH sonic hedgehog
SIRT1 sirtuin 1
SLC39A11 solute carrier family 39, member 11
SMAD3 SMAD family member 3
SNAI2 snail family zinc finger 2
SOX1 SRY (sex determining region Y)-box 1
SOX10 SRY (sex determining region Y)-box 10
SOX2 SRY (sex determining region Y)-box 2
SOX5 SRY (sex determining region Y)-box 5
SOX6 SRY (sex determining region Y)-box 6
SOX9 SRY (sex determining region Y)-box 9
SP1 Sp1 transcription factor
SP7 Sp7 transcription factor
SPP1 secreted phosphoprotein 1
SPTAN1 spectrin, alpha, non-erythrocytic 1
SRY sex determining region Y
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box)
TGFB3 transforming growth factor, beta 3
TSHZ3 teashirt zinc finger homeobox 3
TUBB3 tubulin, beta 3 class III
TWIST1 twist family bHLH transcription factor 1
UBE2I ubiquitin-conjugating enzyme E2I
VPRBP Vpr (HIV-1) binding protein
WDR5 WD repeat domain 5
WT1 Wilms tumor 1
XPO4 exportin 4
YAP1 Yes-associated protein 1
ZNF219 zinc finger protein 219