Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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199 genes differentially expressed following the spaglumic acid-2962 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
AGPAT3 | 1-acylglycerol-3-phosphate O-acyltransferase 3 |
AHSP | alpha hemoglobin stabilizing protein |
ALDH1L1 | aldehyde dehydrogenase 1 family, member L1 |
ALDH3A2 | aldehyde dehydrogenase 3 family, member A2 |
AREG | amphiregulin |
ARMC9 | armadillo repeat containing 9 |
ASPHD1 | aspartate beta-hydroxylase domain containing 1 |
B3GALNT1 | beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group) |
B4GALT2 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2 |
BIK | BCL2-interacting killer (apoptosis-inducing) |
BTN3A1 | butyrophilin, subfamily 3, member A1 |
C6ORF106 | chromosome 6 open reading frame 106 |
CD37 | CD37 molecule |
CDC25C | cell division cycle 25C |
CDC42EP4 | CDC42 effector protein (Rho GTPase binding) 4 |
CEP41 | centrosomal protein 41kDa |
CLCF1 | cardiotrophin-like cytokine factor 1 |
CNNM4 | cyclin and CBS domain divalent metal cation transport mediator 4 |
CNTNAP1 | contactin associated protein 1 |
COLQ | collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase |
COX6A2 | cytochrome c oxidase subunit VIa polypeptide 2 |
CREM | cAMP responsive element modulator |
CUL2 | cullin 2 |
CYP2D6 | cytochrome P450, family 2, subfamily D, polypeptide 6 |
DDX28 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 28 |
DEAF1 | DEAF1 transcription factor |
DGCR11 | DiGeorge syndrome critical region gene 11 (non-protein coding) |
DHODH | dihydroorotate dehydrogenase (quinone) |
DZIP3 | DAZ interacting zinc finger protein 3 |
EFR3B | EFR3 homolog B (S. cerevisiae) |
ERN2 | endoplasmic reticulum to nucleus signaling 2 |
FAM50B | family with sequence similarity 50, member B |
FBXO22 | F-box protein 22 |
FGF18 | fibroblast growth factor 18 |
GPR182 | G protein-coupled receptor 182 |
GRIP2 | glutamate receptor interacting protein 2 |
GRM1 | glutamate receptor, metabotropic 1 |
GRSF1 | G-rich RNA sequence binding factor 1 |
GSK3A | glycogen synthase kinase 3 alpha |
HCFC1R1 | host cell factor C1 regulator 1 (XPO1 dependent) |
HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) |
ICOSLG | inducible T-cell co-stimulator ligand |
IQCE | IQ motif containing E |
JADE3 | jade family PHD finger 3 |
KAT8 | K(lysine) acetyltransferase 8 |
LATS1 | large tumor suppressor kinase 1 |
LDHC | lactate dehydrogenase C |
LYRM9 | LYR motif containing 9 |
MAPRE2 | microtubule-associated protein, RP/EB family, member 2 |
MEOX2 | mesenchyme homeobox 2 |
MFN2 | mitofusin 2 |
MYBPC3 | myosin binding protein C, cardiac |
MYL4 | myosin, light chain 4, alkali; atrial, embryonic |
MYOZ1 | myozenin 1 |
NCAPH2 | non-SMC condensin II complex, subunit H2 |
NFKBIB | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta |
NOX1 | NADPH oxidase 1 |
NQO1 | NAD(P)H dehydrogenase, quinone 1 |
OAZ3 | ornithine decarboxylase antizyme 3 |
PAPOLG | poly(A) polymerase gamma |
PDE12 | phosphodiesterase 12 |
PDLIM2 | PDZ and LIM domain 2 (mystique) |
PDLIM7 | PDZ and LIM domain 7 (enigma) |
PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) |
PRDM10 | PR domain containing 10 |
PRR4 | proline rich 4 (lacrimal) |
PYGB | phosphorylase, glycogen; brain |
QTRT1 | queuine tRNA-ribosyltransferase 1 |
RAD51B | RAD51 paralog B |
RAD52 | RAD52 homolog (S. cerevisiae) |
RBFOX2 | RNA binding protein, fox-1 homolog (C. elegans) 2 |
RGS19 | regulator of G-protein signaling 19 |
RHOD | ras homolog family member D |
RUNX1 | runt-related transcription factor 1 |
SLAMF7 | SLAM family member 7 |
SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 |
SLC29A3 | solute carrier family 29 (equilibrative nucleoside transporter), member 3 |
SLC35F6 | solute carrier family 35, member F6 |
SNCA | synuclein, alpha (non A4 component of amyloid precursor) |
SNX13 | sorting nexin 13 |
SPDEF | SAM pointed domain containing ETS transcription factor |
SPTAN1 | spectrin, alpha, non-erythrocytic 1 |
SSTR4 | somatostatin receptor 4 |
ST3GAL4 | ST3 beta-galactoside alpha-2,3-sialyltransferase 4 |
ST6GAL1 | ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 |
TBKBP1 | TBK1 binding protein 1 |
TBX5 | T-box 5 |
TGFB3 | transforming growth factor, beta 3 |
TMCO3 | transmembrane and coiled-coil domains 3 |
UCN | urocortin |
ULK2 | unc-51 like autophagy activating kinase 2 |
WFDC2 | WAP four-disulfide core domain 2 |
WWC1 | WW and C2 domain containing 1 |
ZBTB33 | zinc finger and BTB domain containing 33 |
ZER1 | zyg-11 related, cell cycle regulator |
ZFYVE9 | zinc finger, FYVE domain containing 9 |
ZNF428 | zinc finger protein 428 |
ZNF510 | zinc finger protein 510 |
ZNF710 | zinc finger protein 710 |
ZNF783 | zinc finger family member 783 |
Symbol | Name |
---|---|
ANAPC2 | anaphase promoting complex subunit 2 |
ANKRD55 | ankyrin repeat domain 55 |
APPL2 | adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2 |
ARRB1 | arrestin, beta 1 |
ATP8B2 | ATPase, aminophospholipid transporter, class I, type 8B, member 2 |
BPGM | 2,3-bisphosphoglycerate mutase |
C1ORF56 | chromosome 1 open reading frame 56 |
C2CD2 | C2 calcium-dependent domain containing 2 |
CDKL3 | cyclin-dependent kinase-like 3 |
CEL | carboxyl ester lipase |
CES3 | carboxylesterase 3 |
CHMP6 | charged multivesicular body protein 6 |
CIC | capicua transcriptional repressor |
CKB | creatine kinase, brain |
CLGN | calmegin |
CTSK | cathepsin K |
DGAT1 | diacylglycerol O-acyltransferase 1 |
DUSP2 | dual specificity phosphatase 2 |
DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 |
EEF2KMT | eukaryotic elongation factor 2 lysine methyltransferase |
FHL3 | four and a half LIM domains 3 |
FKBP9 | FK506 binding protein 9, 63 kDa |
FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) |
GDAP1 | ganglioside induced differentiation associated protein 1 |
GNA12 | guanine nucleotide binding protein (G protein) alpha 12 |
GNL1 | guanine nucleotide binding protein-like 1 |
GNL3LP1 | guanine nucleotide binding protein-like 3 (nucleolar)-like pseudogene 1 |
GPNMB | glycoprotein (transmembrane) nmb |
HERC3 | HECT and RLD domain containing E3 ubiquitin protein ligase 3 |
HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 |
HHLA3 | HERV-H LTR-associating 3 |
HIST1H2BO | histone cluster 1, H2bo |
HIST1H4D | histone cluster 1, H4d |
HRAS | Harvey rat sarcoma viral oncogene homolog |
IFI30 | interferon, gamma-inducible protein 30 |
IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 |
IL4R | interleukin 4 receptor |
IPPK | inositol 1,3,4,5,6-pentakisphosphate 2-kinase |
JUNB | jun B proto-oncogene |
KCNMB3 | potassium channel subfamily M regulatory beta subunit 3 |
KIAA0754 | KIAA0754 |
KIF13B | kinesin family member 13B |
KLF2 | Kruppel-like factor 2 |
LILRA6 | leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6 |
LRP3 | low density lipoprotein receptor-related protein 3 |
LY96 | lymphocyte antigen 96 |
MAFB | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B |
MAP3K8 | mitogen-activated protein kinase kinase kinase 8 |
MAPKBP1 | mitogen-activated protein kinase binding protein 1 |
MMP2 | matrix metallopeptidase 2 |
MRPL44 | mitochondrial ribosomal protein L44 |
MX1 | MX dynamin-like GTPase 1 |
NAT6 | N-acetyltransferase 6 (GCN5-related) |
NBEAL2 | neurobeachin-like 2 |
NHEJ1 | nonhomologous end-joining factor 1 |
NT5C | 5', 3'-nucleotidase, cytosolic |
NT5M | 5',3'-nucleotidase, mitochondrial |
OTUD3 | OTU deubiquitinase 3 |
PIAS3 | protein inhibitor of activated STAT, 3 |
PKN1 | protein kinase N1 |
PNOC | prepronociceptin |
PPM1E | protein phosphatase, Mg2+/Mn2+ dependent, 1E |
PPM1H | protein phosphatase, Mg2+/Mn2+ dependent, 1H |
PROCR | protein C receptor, endothelial |
RAB13 | RAB13, member RAS oncogene family |
RABL6 | RAB, member RAS oncogene family-like 6 |
RPL23AP32 | ribosomal protein L23a pseudogene 32 |
RUSC2 | RUN and SH3 domain containing 2 |
SALL2 | spalt-like transcription factor 2 |
SGCE | sarcoglycan, epsilon |
SGMS1 | sphingomyelin synthase 1 |
SH2D3C | SH2 domain containing 3C |
SLC16A4 | solute carrier family 16, member 4 |
SLC39A1 | solute carrier family 39 (zinc transporter), member 1 |
SMUG1 | single-strand-selective monofunctional uracil-DNA glycosylase 1 |
SPAG4 | sperm associated antigen 4 |
SPIDR | scaffolding protein involved in DNA repair |
TAB1 | TGF-beta activated kinase 1/MAP3K7 binding protein 1 |
TGFBRAP1 | transforming growth factor, beta receptor associated protein 1 |
THBS4 | thrombospondin 4 |
THEM6 | thioesterase superfamily member 6 |
TOR4A | torsin family 4, member A |
TRAF6 | TNF receptor-associated factor 6, E3 ubiquitin protein ligase |
TRIM36 | tripartite motif containing 36 |
TRPS1 | trichorhinophalangeal syndrome I |
TUBA3C | tubulin, alpha 3c |
UBXN2B | UBX domain protein 2B |
UPP1 | uridine phosphorylase 1 |
YIPF3 | Yip1 domain family, member 3 |
ZBED1 | zinc finger, BED-type containing 1 |
ZCWPW1 | zinc finger, CW type with PWWP domain 1 |
ZNF10 | zinc finger protein 10 |
ZNF254 | zinc finger protein 254 |
ZNF506 | zinc finger protein 506 |
ZNF573 | zinc finger protein 573 |
ZNF592 | zinc finger protein 592 |
ZNF701 | zinc finger protein 701 |
ZNF862 | zinc finger protein 862 |
ZNHIT2 | zinc finger, HIT-type containing 2 |