| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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198 genes differentially expressed following the sparteine-2134 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ALS2CL | ALS2 C-terminal like |
| APOM | apolipoprotein M |
| ATF7 | activating transcription factor 7 |
| ATG10 | autophagy related 10 |
| AURKA | aurora kinase A |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A |
| BIN1 | bridging integrator 1 |
| BMP2 | bone morphogenetic protein 2 |
| C4ORF19 | chromosome 4 open reading frame 19 |
| CA1 | carbonic anhydrase I |
| CAMKK2 | calcium/calmodulin-dependent protein kinase kinase 2, beta |
| CAMSAP1 | calmodulin regulated spectrin-associated protein 1 |
| CAMSAP2 | calmodulin regulated spectrin-associated protein family, member 2 |
| CBR3 | carbonyl reductase 3 |
| CCL20 | chemokine (C-C motif) ligand 20 |
| CEP68 | centrosomal protein 68kDa |
| CMAHP | cytidine monophospho-N-acetylneuraminic acid hydroxylase, pseudogene |
| COL4A2 | collagen, type IV, alpha 2 |
| COLQ | collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase |
| CYHR1 | cysteine/histidine-rich 1 |
| DDR1-AS1 | DDR1 antisense RNA 1 (head to head) |
| DEFA6 | defensin, alpha 6, Paneth cell-specific |
| DGCR8 | DGCR8 microprocessor complex subunit |
| EFNA5 | ephrin-A5 |
| FAM105A | family with sequence similarity 105, member A |
| FANCA | Fanconi anemia, complementation group A |
| FCAR | Fc fragment of IgA receptor |
| FGF4 | fibroblast growth factor 4 |
| FLOT1 | flotillin 1 |
| FLRT1 | fibronectin leucine rich transmembrane protein 1 |
| GK | glycerol kinase |
| GK3P | glycerol kinase 3 pseudogene |
| GPATCH4 | G patch domain containing 4 |
| HIF1AN | hypoxia inducible factor 1, alpha subunit inhibitor |
| HIST1H2BG | histone cluster 1, H2bg |
| HOXA6 | homeobox A6 |
| ICA1 | islet cell autoantigen 1, 69kDa |
| IGF2-AS | IGF2 antisense RNA |
| IKZF4 | IKAROS family zinc finger 4 (Eos) |
| IL17RC | interleukin 17 receptor C |
| IL36G | interleukin 36, gamma |
| IL5RA | interleukin 5 receptor, alpha |
| KCTD2 | potassium channel tetramerization domain containing 2 |
| LMF1 | lipase maturation factor 1 |
| LOC257152 | uncharacterized LOC257152 |
| LSM14B | LSM14B, SCD6 homolog B (S. cerevisiae) |
| MAGEA5 | melanoma antigen family A5 |
| MAP4K1 | mitogen-activated protein kinase kinase kinase kinase 1 |
| MEF2C | myocyte enhancer factor 2C |
| MEFV | Mediterranean fever |
| MET | MET proto-oncogene, receptor tyrosine kinase |
| MMP26 | matrix metallopeptidase 26 |
| MS4A4A | membrane-spanning 4-domains, subfamily A, member 4A |
| NARFL | nuclear prelamin A recognition factor-like |
| NDUFA2 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2, 8kDa |
| NEBL | nebulette |
| NF2 | neurofibromin 2 (merlin) |
| NUMA1 | nuclear mitotic apparatus protein 1 |
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa |
| OPTN | optineurin |
| OR2S2 | olfactory receptor, family 2, subfamily S, member 2 (gene/pseudogene) |
| OR7A10 | olfactory receptor, family 7, subfamily A, member 10 |
| PALLD | palladin, cytoskeletal associated protein |
| PEX26 | peroxisomal biogenesis factor 26 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 |
| POU2F2 | POU class 2 homeobox 2 |
| PQLC2 | PQ loop repeat containing 2 |
| PRKAR2A | protein kinase, cAMP-dependent, regulatory, type II, alpha |
| PTPN13 | protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) |
| PVRL2 | poliovirus receptor-related 2 (herpesvirus entry mediator B) |
| PYCRL | pyrroline-5-carboxylate reductase-like |
| RAB6A | RAB6A, member RAS oncogene family |
| RAPGEFL1 | Rap guanine nucleotide exchange factor (GEF)-like 1 |
| RECQL5 | RecQ protein-like 5 |
| RUNX1 | runt-related transcription factor 1 |
| SAMD4A | sterile alpha motif domain containing 4A |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 |
| SGCD | sarcoglycan, delta (35kDa dystrophin-associated glycoprotein) |
| SIRPB1 | signal-regulatory protein beta 1 |
| SLC22A17 | solute carrier family 22, member 17 |
| SLC25A23 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23 |
| SNAP25 | synaptosomal-associated protein, 25kDa |
| SP140 | SP140 nuclear body protein |
| SPOCK2 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2 |
| SPTB | spectrin, beta, erythrocytic |
| STX2 | syntaxin 2 |
| SYT2 | synaptotagmin II |
| TAAR3 | trace amine associated receptor 3 (gene/pseudogene) |
| TAP2 | transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) |
| TAPT1 | transmembrane anterior posterior transformation 1 |
| TIMELESS | timeless circadian clock |
| TJAP1 | tight junction associated protein 1 (peripheral) |
| TMEM144 | transmembrane protein 144 |
| TNFRSF10D | tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain |
| TSPYL2 | TSPY-like 2 |
| TULP1 | tubby like protein 1 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) |
| ZKSCAN8 | zinc finger with KRAB and SCAN domains 8 |
| Symbol | Name |
|---|---|
| A2M | alpha-2-macroglobulin |
| ACADS | acyl-CoA dehydrogenase, C-2 to C-3 short chain |
| AEN | apoptosis enhancing nuclease |
| ANKH | ANKH inorganic pyrophosphate transport regulator |
| APOBEC2 | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2 |
| ASPN | asporin |
| ATP8B2 | ATPase, aminophospholipid transporter, class I, type 8B, member 2 |
| BCL2L2 | BCL2-like 2 |
| BTF3P12 | basic transcription factor 3 pseudogene 12 |
| C17ORF80 | chromosome 17 open reading frame 80 |
| C1RL | complement component 1, r subcomponent-like |
| C6ORF47 | chromosome 6 open reading frame 47 |
| CCDC85C | coiled-coil domain containing 85C |
| CD34 | CD34 molecule |
| CDK3 | cyclin-dependent kinase 3 |
| CDKL3 | cyclin-dependent kinase-like 3 |
| CES3 | carboxylesterase 3 |
| CFP | complement factor properdin |
| CIC | capicua transcriptional repressor |
| CIDEB | cell death-inducing DFFA-like effector b |
| CILP | cartilage intermediate layer protein, nucleotide pyrophosphohydrolase |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 |
| CXORF56 | chromosome X open reading frame 56 |
| CYP17A1 | cytochrome P450, family 17, subfamily A, polypeptide 1 |
| DGKG | diacylglycerol kinase, gamma 90kDa |
| FBP1 | fructose-1,6-bisphosphatase 1 |
| FICD | FIC domain containing |
| GABRB2 | gamma-aminobutyric acid (GABA) A receptor, beta 2 |
| GABRR2 | gamma-aminobutyric acid (GABA) A receptor, rho 2 |
| GNG7 | guanine nucleotide binding protein (G protein), gamma 7 |
| GNL3LP1 | guanine nucleotide binding protein-like 3 (nucleolar)-like pseudogene 1 |
| GPATCH2 | G patch domain containing 2 |
| HIST1H2AE | histone cluster 1, H2ae |
| HIST1H2BI | histone cluster 1, H2bi |
| HOXC8 | homeobox C8 |
| IDI2-AS1 | IDI2 antisense RNA 1 |
| IPPK | inositol 1,3,4,5,6-pentakisphosphate 2-kinase |
| KCNMB3 | potassium channel subfamily M regulatory beta subunit 3 |
| KCNMB4 | potassium channel subfamily M regulatory beta subunit 4 |
| KHDRBS3 | KH domain containing, RNA binding, signal transduction associated 3 |
| KRT8P12 | keratin 8 pseudogene 12 |
| LOC729164 | hCG1732469 |
| LY6E | lymphocyte antigen 6 complex, locus E |
| LY6G6C | lymphocyte antigen 6 complex, locus G6C |
| LZTS3 | leucine zipper, putative tumor suppressor family member 3 |
| MAP3K1 | mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase |
| MAPKBP1 | mitogen-activated protein kinase binding protein 1 |
| MCC | mutated in colorectal cancers |
| MOB3B | MOB kinase activator 3B |
| MTHFSD | methenyltetrahydrofolate synthetase domain containing |
| MYOZ3 | myozenin 3 |
| NECAB3 | N-terminal EF-hand calcium binding protein 3 |
| NFKBIL1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 |
| NHEJ1 | nonhomologous end-joining factor 1 |
| NRGN | neurogranin (protein kinase C substrate, RC3) |
| NTSR1 | neurotensin receptor 1 (high affinity) |
| OXCT2 | 3-oxoacid CoA transferase 2 |
| PARP12 | poly (ADP-ribose) polymerase family, member 12 |
| PCOLCE2 | procollagen C-endopeptidase enhancer 2 |
| PDLIM2 | PDZ and LIM domain 2 (mystique) |
| PGGT1B | protein geranylgeranyltransferase type I, beta subunit |
| PIK3C2B | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta |
| PLTP | phospholipid transfer protein |
| PRR7 | proline rich 7 (synaptic) |
| PRSS53 | protease, serine, 53 |
| RASAL1 | RAS protein activator like 1 (GAP1 like) |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B |
| RNF122 | ring finger protein 122 |
| RRNAD1 | ribosomal RNA adenine dimethylase domain containing 1 |
| SCGB2A2 | secretoglobin, family 2A, member 2 |
| SCUBE3 | signal peptide, CUB domain, EGF-like 3 |
| SHARPIN | SHANK-associated RH domain interactor |
| SIL1 | SIL1 nucleotide exchange factor |
| SLC22A14 | solute carrier family 22, member 14 |
| SLC2A8 | solute carrier family 2 (facilitated glucose transporter), member 8 |
| SOX12 | SRY (sex determining region Y)-box 12 |
| SPINK2 | serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) |
| SPINT1 | serine peptidase inhibitor, Kunitz type 1 |
| STX5 | syntaxin 5 |
| SV2A | synaptic vesicle glycoprotein 2A |
| TAB1 | TGF-beta activated kinase 1/MAP3K7 binding protein 1 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa |
| THBS3 | thrombospondin 3 |
| TMEM180 | transmembrane protein 180 |
| TMEM212 | transmembrane protein 212 |
| TMEM53 | transmembrane protein 53 |
| TNFRSF12A | tumor necrosis factor receptor superfamily, member 12A |
| TOLLIP | toll interacting protein |
| TRAF2 | TNF receptor-associated factor 2 |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein |
| TTC23 | tetratricopeptide repeat domain 23 |
| TTC26 | tetratricopeptide repeat domain 26 |
| WNT10B | wingless-type MMTV integration site family, member 10B |
| ZBTB25 | zinc finger and BTB domain containing 25 |
| ZDHHC14 | zinc finger, DHHC-type containing 14 |
| ZKSCAN3 | zinc finger with KRAB and SCAN domains 3 |
| ZNF10 | zinc finger protein 10 |
| ZNF749 | zinc finger protein 749 |
| ZSCAN31 | zinc finger and SCAN domain containing 31 |