sparteine-2134 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the sparteine-2134 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ALS2CL ALS2 C-terminal like
APOM apolipoprotein M
ATF7 activating transcription factor 7
ATG10 autophagy related 10
AURKA aurora kinase A
BAZ2A bromodomain adjacent to zinc finger domain, 2A
BIN1 bridging integrator 1
BMP2 bone morphogenetic protein 2
C4ORF19 chromosome 4 open reading frame 19
CA1 carbonic anhydrase I
CAMKK2 calcium/calmodulin-dependent protein kinase kinase 2, beta
CAMSAP1 calmodulin regulated spectrin-associated protein 1
CAMSAP2 calmodulin regulated spectrin-associated protein family, member 2
CBR3 carbonyl reductase 3
CCL20 chemokine (C-C motif) ligand 20
CEP68 centrosomal protein 68kDa
CMAHP cytidine monophospho-N-acetylneuraminic acid hydroxylase, pseudogene
COL4A2 collagen, type IV, alpha 2
COLQ collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase
CYHR1 cysteine/histidine-rich 1
DDR1-AS1 DDR1 antisense RNA 1 (head to head)
DEFA6 defensin, alpha 6, Paneth cell-specific
DGCR8 DGCR8 microprocessor complex subunit
EFNA5 ephrin-A5
FAM105A family with sequence similarity 105, member A
FANCA Fanconi anemia, complementation group A
FCAR Fc fragment of IgA receptor
FGF4 fibroblast growth factor 4
FLOT1 flotillin 1
FLRT1 fibronectin leucine rich transmembrane protein 1
GK glycerol kinase
GK3P glycerol kinase 3 pseudogene
GPATCH4 G patch domain containing 4
HIF1AN hypoxia inducible factor 1, alpha subunit inhibitor
HIST1H2BG histone cluster 1, H2bg
HOXA6 homeobox A6
ICA1 islet cell autoantigen 1, 69kDa
IGF2-AS IGF2 antisense RNA
IKZF4 IKAROS family zinc finger 4 (Eos)
IL17RC interleukin 17 receptor C
IL36G interleukin 36, gamma
IL5RA interleukin 5 receptor, alpha
KCTD2 potassium channel tetramerization domain containing 2
LMF1 lipase maturation factor 1
LOC257152 uncharacterized LOC257152
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
MAGEA5 melanoma antigen family A5
MAP4K1 mitogen-activated protein kinase kinase kinase kinase 1
MEF2C myocyte enhancer factor 2C
MEFV Mediterranean fever
MET MET proto-oncogene, receptor tyrosine kinase
MMP26 matrix metallopeptidase 26
MS4A4A membrane-spanning 4-domains, subfamily A, member 4A
NARFL nuclear prelamin A recognition factor-like
NDUFA2 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2, 8kDa
NEBL nebulette
NF2 neurofibromin 2 (merlin)
NUMA1 nuclear mitotic apparatus protein 1
OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa
OPTN optineurin
OR2S2 olfactory receptor, family 2, subfamily S, member 2 (gene/pseudogene)
OR7A10 olfactory receptor, family 7, subfamily A, member 10
PALLD palladin, cytoskeletal associated protein
PEX26 peroxisomal biogenesis factor 26
PHLDA1 pleckstrin homology-like domain, family A, member 1
POU2F2 POU class 2 homeobox 2
PQLC2 PQ loop repeat containing 2
PRKAR2A protein kinase, cAMP-dependent, regulatory, type II, alpha
PTPN13 protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase)
PVRL2 poliovirus receptor-related 2 (herpesvirus entry mediator B)
PYCRL pyrroline-5-carboxylate reductase-like
RAB6A RAB6A, member RAS oncogene family
RAPGEFL1 Rap guanine nucleotide exchange factor (GEF)-like 1
RECQL5 RecQ protein-like 5
RUNX1 runt-related transcription factor 1
SAMD4A sterile alpha motif domain containing 4A
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SGCD sarcoglycan, delta (35kDa dystrophin-associated glycoprotein)
SIRPB1 signal-regulatory protein beta 1
SLC22A17 solute carrier family 22, member 17
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
SNAP25 synaptosomal-associated protein, 25kDa
SP140 SP140 nuclear body protein
SPOCK2 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
SPTB spectrin, beta, erythrocytic
STX2 syntaxin 2
SYT2 synaptotagmin II
TAAR3 trace amine associated receptor 3 (gene/pseudogene)
TAP2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
TAPT1 transmembrane anterior posterior transformation 1
TIMELESS timeless circadian clock
TJAP1 tight junction associated protein 1 (peripheral)
TMEM144 transmembrane protein 144
TNFRSF10D tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain
TSPYL2 TSPY-like 2
TULP1 tubby like protein 1
UBR4 ubiquitin protein ligase E3 component n-recognin 4
VPS13B vacuolar protein sorting 13 homolog B (yeast)
ZKSCAN8 zinc finger with KRAB and SCAN domains 8

decreased expression

Symbol Name
A2M alpha-2-macroglobulin
ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain
AEN apoptosis enhancing nuclease
ANKH ANKH inorganic pyrophosphate transport regulator
APOBEC2 apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2
ASPN asporin
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2
BCL2L2 BCL2-like 2
BTF3P12 basic transcription factor 3 pseudogene 12
C17ORF80 chromosome 17 open reading frame 80
C1RL complement component 1, r subcomponent-like
C6ORF47 chromosome 6 open reading frame 47
CCDC85C coiled-coil domain containing 85C
CD34 CD34 molecule
CDK3 cyclin-dependent kinase 3
CDKL3 cyclin-dependent kinase-like 3
CES3 carboxylesterase 3
CFP complement factor properdin
CIC capicua transcriptional repressor
CIDEB cell death-inducing DFFA-like effector b
CILP cartilage intermediate layer protein, nucleotide pyrophosphohydrolase
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1
CXORF56 chromosome X open reading frame 56
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
DGKG diacylglycerol kinase, gamma 90kDa
FBP1 fructose-1,6-bisphosphatase 1
FICD FIC domain containing
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
GABRR2 gamma-aminobutyric acid (GABA) A receptor, rho 2
GNG7 guanine nucleotide binding protein (G protein), gamma 7
GNL3LP1 guanine nucleotide binding protein-like 3 (nucleolar)-like pseudogene 1
GPATCH2 G patch domain containing 2
HIST1H2AE histone cluster 1, H2ae
HIST1H2BI histone cluster 1, H2bi
HOXC8 homeobox C8
IDI2-AS1 IDI2 antisense RNA 1
IPPK inositol 1,3,4,5,6-pentakisphosphate 2-kinase
KCNMB3 potassium channel subfamily M regulatory beta subunit 3
KCNMB4 potassium channel subfamily M regulatory beta subunit 4
KHDRBS3 KH domain containing, RNA binding, signal transduction associated 3
KRT8P12 keratin 8 pseudogene 12
LOC729164 hCG1732469
LY6E lymphocyte antigen 6 complex, locus E
LY6G6C lymphocyte antigen 6 complex, locus G6C
LZTS3 leucine zipper, putative tumor suppressor family member 3
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MAPKBP1 mitogen-activated protein kinase binding protein 1
MCC mutated in colorectal cancers
MOB3B MOB kinase activator 3B
MTHFSD methenyltetrahydrofolate synthetase domain containing
MYOZ3 myozenin 3
NECAB3 N-terminal EF-hand calcium binding protein 3
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NHEJ1 nonhomologous end-joining factor 1
NRGN neurogranin (protein kinase C substrate, RC3)
NTSR1 neurotensin receptor 1 (high affinity)
OXCT2 3-oxoacid CoA transferase 2
PARP12 poly (ADP-ribose) polymerase family, member 12
PCOLCE2 procollagen C-endopeptidase enhancer 2
PDLIM2 PDZ and LIM domain 2 (mystique)
PGGT1B protein geranylgeranyltransferase type I, beta subunit
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta
PLTP phospholipid transfer protein
PRR7 proline rich 7 (synaptic)
PRSS53 protease, serine, 53
RASAL1 RAS protein activator like 1 (GAP1 like)
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RNF122 ring finger protein 122
RRNAD1 ribosomal RNA adenine dimethylase domain containing 1
SCGB2A2 secretoglobin, family 2A, member 2
SCUBE3 signal peptide, CUB domain, EGF-like 3
SHARPIN SHANK-associated RH domain interactor
SIL1 SIL1 nucleotide exchange factor
SLC22A14 solute carrier family 22, member 14
SLC2A8 solute carrier family 2 (facilitated glucose transporter), member 8
SOX12 SRY (sex determining region Y)-box 12
SPINK2 serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor)
SPINT1 serine peptidase inhibitor, Kunitz type 1
STX5 syntaxin 5
SV2A synaptic vesicle glycoprotein 2A
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
THBS3 thrombospondin 3
TMEM180 transmembrane protein 180
TMEM212 transmembrane protein 212
TMEM53 transmembrane protein 53
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A
TOLLIP toll interacting protein
TRAF2 TNF receptor-associated factor 2
TRPC4AP transient receptor potential cation channel, subfamily C, member 4 associated protein
TTC23 tetratricopeptide repeat domain 23
TTC26 tetratricopeptide repeat domain 26
WNT10B wingless-type MMTV integration site family, member 10B
ZBTB25 zinc finger and BTB domain containing 25
ZDHHC14 zinc finger, DHHC-type containing 14
ZKSCAN3 zinc finger with KRAB and SCAN domains 3
ZNF10 zinc finger protein 10
ZNF749 zinc finger protein 749
ZSCAN31 zinc finger and SCAN domain containing 31