| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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196 genes differentially expressed following the sparteine-4391 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACAA2 | acetyl-CoA acyltransferase 2 |
| ACAP1 | ArfGAP with coiled-coil, ankyrin repeat and PH domains 1 |
| AIM2 | absent in melanoma 2 |
| AKAP13 | A kinase (PRKA) anchor protein 13 |
| ANTXR1 | anthrax toxin receptor 1 |
| ARL4D | ADP-ribosylation factor-like 4D |
| ASIC1 | acid sensing (proton gated) ion channel 1 |
| BMP8B | bone morphogenetic protein 8b |
| C1ORF68 | chromosome 1 open reading frame 68 |
| C21ORF2 | chromosome 21 open reading frame 2 |
| C8A | complement component 8, alpha polypeptide |
| CD83 | CD83 molecule |
| CFHR4 | complement factor H-related 4 |
| CFLAR | CASP8 and FADD-like apoptosis regulator |
| CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) |
| CILP | cartilage intermediate layer protein, nucleotide pyrophosphohydrolase |
| CLDN11 | claudin 11 |
| COL6A1 | collagen, type VI, alpha 1 |
| CSF1 | colony stimulating factor 1 (macrophage) |
| CSF2 | colony stimulating factor 2 (granulocyte-macrophage) |
| CUX2 | cut-like homeobox 2 |
| DCN | decorin |
| DPP4 | dipeptidyl-peptidase 4 |
| EDN1 | endothelin 1 |
| EFHC2 | EF-hand domain (C-terminal) containing 2 |
| EXOSC2 | exosome component 2 |
| FMO3 | flavin containing monooxygenase 3 |
| FN1 | fibronectin 1 |
| FOXE1 | forkhead box E1 |
| FOXE3 | forkhead box E3 |
| FXYD5 | FXYD domain containing ion transport regulator 5 |
| GH1 | growth hormone 1 |
| GNG7 | guanine nucleotide binding protein (G protein), gamma 7 |
| GRIK5 | glutamate receptor, ionotropic, kainate 5 |
| GRM2 | glutamate receptor, metabotropic 2 |
| HBEGF | heparin-binding EGF-like growth factor |
| HEMK1 | HemK methyltransferase family member 1 |
| HFE | hemochromatosis |
| HIST1H2BN | histone cluster 1, H2bn |
| HIST1H4F | histone cluster 1, H4f |
| HPGD | hydroxyprostaglandin dehydrogenase 15-(NAD) |
| HSF2BP | heat shock transcription factor 2 binding protein |
| IGFBP5 | insulin-like growth factor binding protein 5 |
| IMPG2 | interphotoreceptor matrix proteoglycan 2 |
| ITGA7 | integrin, alpha 7 |
| ITM2C | integral membrane protein 2C |
| KANSL3 | KAT8 regulatory NSL complex subunit 3 |
| KCNH1 | potassium channel, voltage gated eag related subfamily H, member 1 |
| LEFTY1 | left-right determination factor 1 |
| LOC100286895 | cell division cycle 27 homolog pseudogene |
| LRRC37BP1 | leucine rich repeat containing 37B pseudogene 1 |
| MEF2D | myocyte enhancer factor 2D |
| MEG3 | maternally expressed 3 (non-protein coding) |
| MRC2 | mannose receptor, C type 2 |
| MYEF2 | myelin expression factor 2 |
| NPY | neuropeptide Y |
| NTF3 | neurotrophin 3 |
| OR1G1 | olfactory receptor, family 1, subfamily G, member 1 |
| PAK4 | p21 protein (Cdc42/Rac)-activated kinase 4 |
| PBX2 | pre-B-cell leukemia homeobox 2 |
| PCDH12 | protocadherin 12 |
| PILRA | paired immunoglobin-like type 2 receptor alpha |
| PLA2G6 | phospholipase A2, group VI (cytosolic, calcium-independent) |
| PNPLA3 | patatin-like phospholipase domain containing 3 |
| PON1 | paraoxonase 1 |
| PRODH2 | proline dehydrogenase (oxidase) 2 |
| PRTN3 | proteinase 3 |
| PTCRA | pre T-cell antigen receptor alpha |
| PTGER2 | prostaglandin E receptor 2 (subtype EP2), 53kDa |
| PTPRM | protein tyrosine phosphatase, receptor type, M |
| RASIP1 | Ras interacting protein 1 |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B |
| RHAG | Rh-associated glycoprotein |
| RIF1 | replication timing regulatory factor 1 |
| RIN3 | Ras and Rab interactor 3 |
| RPS28 | ribosomal protein S28 |
| SEC24D | SEC24 family member D |
| SGCD | sarcoglycan, delta (35kDa dystrophin-associated glycoprotein) |
| SH3BP2 | SH3-domain binding protein 2 |
| SLC30A3 | solute carrier family 30 (zinc transporter), member 3 |
| SNAP25 | synaptosomal-associated protein, 25kDa |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) |
| SOX2 | SRY (sex determining region Y)-box 2 |
| SPEG | SPEG complex locus |
| STK24 | serine/threonine kinase 24 |
| SYDE1 | synapse defective 1, Rho GTPase, homolog 1 (C. elegans) |
| TAF1 | TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa |
| TFDP3 | transcription factor Dp family, member 3 |
| TNPO2 | transportin 2 |
| TP53I11 | tumor protein p53 inducible protein 11 |
| TPP1 | tripeptidyl peptidase I |
| TRPM8 | transient receptor potential cation channel, subfamily M, member 8 |
| TTN | titin |
| TUBB2B | tubulin, beta 2B class IIb |
| VCAN | versican |
| VNN2 | vanin 2 |
| VPS9D1 | VPS9 domain containing 1 |
| WFDC8 | WAP four-disulfide core domain 8 |
| ZNF362 | zinc finger protein 362 |
| Symbol | Name |
|---|---|
| ACYP2 | acylphosphatase 2, muscle type |
| AHNAK2 | AHNAK nucleoprotein 2 |
| ANKFY1 | ankyrin repeat and FYVE domain containing 1 |
| ANXA2P3 | annexin A2 pseudogene 3 |
| AP1S1 | adaptor-related protein complex 1, sigma 1 subunit |
| BGLAP | bone gamma-carboxyglutamate (gla) protein |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 |
| BTF3P12 | basic transcription factor 3 pseudogene 12 |
| C10ORF95 | chromosome 10 open reading frame 95 |
| C11ORF30 | chromosome 11 open reading frame 30 |
| C11ORF68 | chromosome 11 open reading frame 68 |
| C14ORF93 | chromosome 14 open reading frame 93 |
| C2ORF27A | chromosome 2 open reading frame 27A |
| CASD1 | CAS1 domain containing 1 |
| CBL | Cbl proto-oncogene, E3 ubiquitin protein ligase |
| CHKB | choline kinase beta |
| CNR2 | cannabinoid receptor 2 (macrophage) |
| CRIP1 | cysteine-rich protein 1 (intestinal) |
| DBF4B | DBF4 zinc finger B |
| DDX58 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 |
| DGKQ | diacylglycerol kinase, theta 110kDa |
| DIXDC1 | DIX domain containing 1 |
| EDAR | ectodysplasin A receptor |
| EGFL7 | EGF-like-domain, multiple 7 |
| ELOVL4 | ELOVL fatty acid elongase 4 |
| ERCC2 | excision repair cross-complementation group 2 |
| ETAA1 | Ewing tumor-associated antigen 1 |
| EXD3 | exonuclease 3'-5' domain containing 3 |
| F2R | coagulation factor II (thrombin) receptor |
| FAM204A | family with sequence similarity 204, member A |
| FBXO2 | F-box protein 2 |
| FBXO5 | F-box protein 5 |
| GEMIN8 | gem (nuclear organelle) associated protein 8 |
| GJA9 | gap junction protein, alpha 9, 59kDa |
| GNAZ | guanine nucleotide binding protein (G protein), alpha z polypeptide |
| GPR143 | G protein-coupled receptor 143 |
| HDAC11 | histone deacetylase 11 |
| HERC5 | HECT and RLD domain containing E3 ubiquitin protein ligase 5 |
| HHAT | hedgehog acyltransferase |
| HIRA | histone cell cycle regulator |
| HIST1H1D | histone cluster 1, H1d |
| HIST1H2BM | histone cluster 1, H2bm |
| HIST2H2AA3 | histone cluster 2, H2aa3 |
| HOXA4 | homeobox A4 |
| HOXC5 | homeobox C5 |
| IFI27 | interferon, alpha-inducible protein 27 |
| IFI6 | interferon, alpha-inducible protein 6 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 |
| IFT54 | intraflagellar transport 54 |
| IL12RB1 | interleukin 12 receptor, beta 1 |
| IL4R | interleukin 4 receptor |
| INF2 | inverted formin, FH2 and WH2 domain containing |
| INO80D | INO80 complex subunit D |
| INPP1 | inositol polyphosphate-1-phosphatase |
| KANSL1L | KAT8 regulatory NSL complex subunit 1-like |
| KCNK15 | potassium channel, two pore domain subfamily K, member 15 |
| KCNN1 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1 |
| KITLG | KIT ligand |
| KPNA5 | karyopherin alpha 5 (importin alpha 6) |
| LARP6 | La ribonucleoprotein domain family, member 6 |
| LHPP | phospholysine phosphohistidine inorganic pyrophosphate phosphatase |
| LIF | leukemia inhibitory factor |
| LIN7A | lin-7 homolog A (C. elegans) |
| LMNB1 | lamin B1 |
| MAP3K1 | mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase |
| MBNL3 | muscleblind-like splicing regulator 3 |
| MEFV | Mediterranean fever |
| NAT6 | N-acetyltransferase 6 (GCN5-related) |
| NIPAL2 | NIPA-like domain containing 2 |
| NPY1R | neuropeptide Y receptor Y1 |
| NUP62CL | nucleoporin 62kDa C-terminal like |
| NXPE3 | neurexophilin and PC-esterase domain family, member 3 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa |
| OSGIN1 | oxidative stress induced growth inhibitor 1 |
| PEX26 | peroxisomal biogenesis factor 26 |
| PRAMEF11 | PRAME family member 11 |
| PRR4 | proline rich 4 (lacrimal) |
| PVRL3 | poliovirus receptor-related 3 |
| RCAN3 | RCAN family member 3 |
| RGS19 | regulator of G-protein signaling 19 |
| SIX1 | SIX homeobox 1 |
| SLC2A11 | solute carrier family 2 (facilitated glucose transporter), member 11 |
| SNX16 | sorting nexin 16 |
| SP1 | Sp1 transcription factor |
| SRD5A3 | steroid 5 alpha-reductase 3 |
| TFAP4 | transcription factor AP-4 (activating enhancer binding protein 4) |
| THNSL1 | threonine synthase-like 1 (S. cerevisiae) |
| TMA16 | translation machinery associated 16 homolog (S. cerevisiae) |
| TMEM2 | transmembrane protein 2 |
| TRABD | TraB domain containing |
| TRIM36 | tripartite motif containing 36 |
| TSGA10 | testis specific, 10 |
| UPP1 | uridine phosphorylase 1 |
| VASH2 | vasohibin 2 |
| ZIC3 | Zic family member 3 |
| ZNF286A | zinc finger protein 286A |
| ZNF747 | zinc finger protein 747 |
