| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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195 genes differentially expressed following the sparteine-4568 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| A2M | alpha-2-macroglobulin |
| ABCC2 | ATP-binding cassette, sub-family C (CFTR/MRP), member 2 |
| ACTN2 | actinin, alpha 2 |
| ADAMTS7 | ADAM metallopeptidase with thrombospondin type 1 motif, 7 |
| ALDH1A2 | aldehyde dehydrogenase 1 family, member A2 |
| ARTN | artemin |
| ASPHD1 | aspartate beta-hydroxylase domain containing 1 |
| B4GALT1 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 |
| C11ORF63 | chromosome 11 open reading frame 63 |
| C17ORF59 | chromosome 17 open reading frame 59 |
| C1ORF21 | chromosome 1 open reading frame 21 |
| CACNA1I | calcium channel, voltage-dependent, T type, alpha 1I subunit |
| CADM3 | cell adhesion molecule 3 |
| CAMK4 | calcium/calmodulin-dependent protein kinase IV |
| CASP2 | caspase 2, apoptosis-related cysteine peptidase |
| CCDC181 | coiled-coil domain containing 181 |
| CD33 | CD33 molecule |
| CD86 | CD86 molecule |
| CFAP45 | cilia and flagella associated protein 45 |
| CLEC4A | C-type lectin domain family 4, member A |
| COMT | catechol-O-methyltransferase |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 |
| CYP3A4 | cytochrome P450, family 3, subfamily A, polypeptide 4 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 |
| DCTN1 | dynactin 1 |
| EDNRB | endothelin receptor type B |
| EDRF1 | erythroid differentiation regulatory factor 1 |
| EFCAB6 | EF-hand calcium binding domain 6 |
| ETV1 | ets variant 1 |
| FAM174B | family with sequence similarity 174, member B |
| FGF5 | fibroblast growth factor 5 |
| FRMD1 | FERM domain containing 1 |
| FRZB | frizzled-related protein |
| FUT7 | fucosyltransferase 7 (alpha (1,3) fucosyltransferase) |
| GGT1 | gamma-glutamyltransferase 1 |
| GJA9 | gap junction protein, alpha 9, 59kDa |
| GK2 | glycerol kinase 2 |
| GLS2 | glutaminase 2 (liver, mitochondrial) |
| GNG7 | guanine nucleotide binding protein (G protein), gamma 7 |
| GPR17 | G protein-coupled receptor 17 |
| GPSM3 | G-protein signaling modulator 3 |
| GREM2 | gremlin 2, DAN family BMP antagonist |
| HIST1H1E | histone cluster 1, H1e |
| HIST1H2AL | histone cluster 1, H2al |
| HLA-DRB4 | major histocompatibility complex, class II, DR beta 4 |
| HOXD9 | homeobox D9 |
| HSPB3 | heat shock 27kDa protein 3 |
| ICA1 | islet cell autoantigen 1, 69kDa |
| IFT140 | intraflagellar transport 140 |
| IL1RN | interleukin 1 receptor antagonist |
| IL36RN | interleukin 36 receptor antagonist |
| ING4 | inhibitor of growth family, member 4 |
| KCNAB1 | potassium channel, voltage gated subfamily A regulatory beta subunit 1 |
| KRT14 | keratin 14, type I |
| KRT34 | keratin 34, type I |
| LMOD1 | leiomodin 1 (smooth muscle) |
| LOC440895 | two pore channel 3 pseudogene |
| LRRK1 | leucine-rich repeat kinase 1 |
| MMP25 | matrix metallopeptidase 25 |
| MTHFR | methylenetetrahydrofolate reductase (NAD(P)H) |
| MUC4 | mucin 4, cell surface associated |
| N4BP1 | NEDD4 binding protein 1 |
| NHLH2 | nescient helix loop helix 2 |
| OR10H1 | olfactory receptor, family 10, subfamily H, member 1 |
| OR52A1 | olfactory receptor, family 52, subfamily A, member 1 |
| P2RY1 | purinergic receptor P2Y, G-protein coupled, 1 |
| PCDH12 | protocadherin 12 |
| PCDHB17P | protocadherin beta 17 pseudogene |
| PDGFB | platelet-derived growth factor beta polypeptide |
| PICALM | phosphatidylinositol binding clathrin assembly protein |
| PKNOX1 | PBX/knotted 1 homeobox 1 |
| POU5F1B | POU class 5 homeobox 1B |
| PPP1R7 | protein phosphatase 1, regulatory subunit 7 |
| PQLC2 | PQ loop repeat containing 2 |
| RABGAP1L | RAB GTPase activating protein 1-like |
| RANBP1 | RAN binding protein 1 |
| RIMBP2 | RIMS binding protein 2 |
| RNF6 | ring finger protein (C3H2C3 type) 6 |
| RPL10L | ribosomal protein L10-like |
| RS1 | retinoschisin 1 |
| SAA3P | serum amyloid A3 pseudogene |
| SCN11A | sodium channel, voltage gated, type XI alpha subunit |
| SERHL2 | serine hydrolase-like 2 |
| SERPINI2 | serpin peptidase inhibitor, clade I (pancpin), member 2 |
| SFRP5 | secreted frizzled-related protein 5 |
| SLC16A5 | solute carrier family 16 (monocarboxylate transporter), member 5 |
| SLCO2A1 | solute carrier organic anion transporter family, member 2A1 |
| SMPDL3B | sphingomyelin phosphodiesterase, acid-like 3B |
| SPRED2 | sprouty-related, EVH1 domain containing 2 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 |
| TAOK2 | TAO kinase 2 |
| TBXA2R | thromboxane A2 receptor |
| THEMIS2 | thymocyte selection associated family member 2 |
| TLR2 | toll-like receptor 2 |
| TREM1 | triggering receptor expressed on myeloid cells 1 |
| TROVE2 | TROVE domain family, member 2 |
| TXNRD2 | thioredoxin reductase 2 |
| ZNF268 | zinc finger protein 268 |
| Symbol | Name |
|---|---|
| AGO1 | argonaute RISC catalytic component 1 |
| APBB3 | amyloid beta (A4) precursor protein-binding, family B, member 3 |
| ARHGAP12 | Rho GTPase activating protein 12 |
| ARHGEF16 | Rho guanine nucleotide exchange factor (GEF) 16 |
| ATAD5 | ATPase family, AAA domain containing 5 |
| B3GALT4 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4 |
| C1QTNF1 | C1q and tumor necrosis factor related protein 1 |
| C5ORF45 | chromosome 5 open reading frame 45 |
| CA5BP1 | carbonic anhydrase VB pseudogene 1 |
| CDT1 | chromatin licensing and DNA replication factor 1 |
| CEP83 | centrosomal protein 83kDa |
| CHM | choroideremia (Rab escort protein 1) |
| CLUHP3 | clustered mitochondria (cluA/CLU1) homolog pseudogene 3 |
| CNIH3 | cornichon family AMPA receptor auxiliary protein 3 |
| CNNM4 | cyclin and CBS domain divalent metal cation transport mediator 4 |
| COL21A1 | collagen, type XXI, alpha 1 |
| CTC1 | CTS telomere maintenance complex component 1 |
| DTX2 | deltex 2, E3 ubiquitin ligase |
| DYNC2H1 | dynein, cytoplasmic 2, heavy chain 1 |
| EDC3 | enhancer of mRNA decapping 3 |
| EDC4 | enhancer of mRNA decapping 4 |
| ENTPD3 | ectonucleoside triphosphate diphosphohydrolase 3 |
| ENTPD5 | ectonucleoside triphosphate diphosphohydrolase 5 |
| EPHA4 | EPH receptor A4 |
| EPHX2 | epoxide hydrolase 2, cytoplasmic |
| ERCC2 | excision repair cross-complementation group 2 |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| EVPL | envoplakin |
| FAM114A2 | family with sequence similarity 114, member A2 |
| FANCC | Fanconi anemia, complementation group C |
| FBXL7 | F-box and leucine-rich repeat protein 7 |
| FOXJ2 | forkhead box J2 |
| GALNT14 | polypeptide N-acetylgalactosaminyltransferase 14 |
| GNB1L | guanine nucleotide binding protein (G protein), beta polypeptide 1-like |
| GRTP1 | growth hormone regulated TBC protein 1 |
| GTF2A1 | general transcription factor IIA, 1, 19/37kDa |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 |
| HIST1H4E | histone cluster 1, H4e |
| HIST2H2AA3 | histone cluster 2, H2aa3 |
| HOOK1 | hook microtubule-tethering protein 1 |
| HOXC10 | homeobox C10 |
| HSPA2 | heat shock 70kDa protein 2 |
| IREB2 | iron-responsive element binding protein 2 |
| ITGA10 | integrin, alpha 10 |
| ITK | IL2-inducible T-cell kinase |
| KCNJ12 | potassium channel, inwardly rectifying subfamily J, member 12 |
| KIAA1107 | KIAA1107 |
| KRT6A | keratin 6A, type II |
| LINC00597 | long intergenic non-protein coding RNA 597 |
| LOC202181 | SUMO-interacting motifs containing 1 pseudogene |
| LOC257152 | uncharacterized LOC257152 |
| LPAR6 | lysophosphatidic acid receptor 6 |
| MAP1S | microtubule-associated protein 1S |
| MFSD6 | major facilitator superfamily domain containing 6 |
| MGAT4A | mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A |
| MT1M | metallothionein 1M |
| MTHFSD | methenyltetrahydrofolate synthetase domain containing |
| MYH15 | myosin, heavy chain 15 |
| NBEAL2 | neurobeachin-like 2 |
| NT5M | 5',3'-nucleotidase, mitochondrial |
| OPA3 | optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia) |
| P2RY6 | pyrimidinergic receptor P2Y, G-protein coupled, 6 |
| PARP3 | poly (ADP-ribose) polymerase family, member 3 |
| PCBP4 | poly(rC) binding protein 4 |
| PEX13 | peroxisomal biogenesis factor 13 |
| PID1 | phosphotyrosine interaction domain containing 1 |
| PITPNM1 | phosphatidylinositol transfer protein, membrane-associated 1 |
| PLEKHF1 | pleckstrin homology domain containing, family F (with FYVE domain) member 1 |
| POM121 | POM121 transmembrane nucleoporin |
| RAB33B | RAB33B, member RAS oncogene family |
| RAB36 | RAB36, member RAS oncogene family |
| RHOBTB2 | Rho-related BTB domain containing 2 |
| RPS14P3 | ribosomal protein S14 pseudogene 3 |
| RRNAD1 | ribosomal RNA adenine dimethylase domain containing 1 |
| SAYSD1 | SAYSVFN motif domain containing 1 |
| SERTAD3 | SERTA domain containing 3 |
| SETD1B | SET domain containing 1B |
| SETD8 | SET domain containing (lysine methyltransferase) 8 |
| SLC25A40 | solute carrier family 25, member 40 |
| SLC4A8 | solute carrier family 4, sodium bicarbonate cotransporter, member 8 |
| SNPH | syntaphilin |
| SRD5A3 | steroid 5 alpha-reductase 3 |
| STAC | SH3 and cysteine rich domain |
| SUZ12P1 | suppressor of zeste 12 homolog pseudogene 1 |
| SYNPO | synaptopodin |
| TUBA3C | tubulin, alpha 3c |
| UAP1L1 | UDP-N-acetylglucosamine pyrophosphorylase 1 like 1 |
| XRCC3 | X-ray repair complementing defective repair in Chinese hamster cells 3 |
| ZNF180 | zinc finger protein 180 |
| ZNF214 | zinc finger protein 214 |
| ZNF350 | zinc finger protein 350 |
| ZNF37BP | zinc finger protein 37B, pseudogene |
| ZNF623 | zinc finger protein 623 |
| ZNF701 | zinc finger protein 701 |
| ZNF768 | zinc finger protein 768 |
| ZW10 | zw10 kinetochore protein |
