spasticity Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description A motor disorder characterized by a velocity-dependent increase in tonic stretch reflexes with increased muscle tone, exaggerated (hyperexcitable) tendon reflexes. (Human Phenotype Ontology, HP_0001257)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0012051
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Genes

2 gene mutations causing the spasticity phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
HSPD1 heat shock 60kDa protein 1 (chaperonin)
PMP22 peripheral myelin protein 22