| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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199 genes differentially expressed following the spectinomycin-3327 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| A2M | alpha-2-macroglobulin |
| ADAMTS13 | ADAM metallopeptidase with thrombospondin type 1 motif, 13 |
| ADGRA2 | adhesion G protein-coupled receptor A2 |
| ALCAM | activated leukocyte cell adhesion molecule |
| ALDH3B2 | aldehyde dehydrogenase 3 family, member B2 |
| ALDOB | aldolase B, fructose-bisphosphate |
| APAF1 | apoptotic peptidase activating factor 1 |
| APBA2 | amyloid beta (A4) precursor protein-binding, family A, member 2 |
| ARID1A | AT rich interactive domain 1A (SWI-like) |
| BTF3P11 | basic transcription factor 3 pseudogene 11 |
| C1QB | complement component 1, q subcomponent, B chain |
| C3AR1 | complement component 3a receptor 1 |
| CACNA1I | calcium channel, voltage-dependent, T type, alpha 1I subunit |
| CACNB2 | calcium channel, voltage-dependent, beta 2 subunit |
| CASP2 | caspase 2, apoptosis-related cysteine peptidase |
| CDKAL1 | CDK5 regulatory subunit associated protein 1-like 1 |
| CES3 | carboxylesterase 3 |
| CFTR | cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) |
| CHRNA6 | cholinergic receptor, nicotinic, alpha 6 (neuronal) |
| COL5A2 | collagen, type V, alpha 2 |
| CRYBB2P1 | crystallin, beta B2 pseudogene 1 |
| CXCL12 | chemokine (C-X-C motif) ligand 12 |
| CYP2A7 | cytochrome P450, family 2, subfamily A, polypeptide 7 |
| DENND5B | DENN/MADD domain containing 5B |
| DHX34 | DEAH (Asp-Glu-Ala-His) box polypeptide 34 |
| DNAJA4 | DnaJ (Hsp40) homolog, subfamily A, member 4 |
| EDNRA | endothelin receptor type A |
| EGR3 | early growth response 3 |
| EPS8L3 | EPS8-like 3 |
| FAM131A | family with sequence similarity 131, member A |
| FAXDC2 | fatty acid hydroxylase domain containing 2 |
| FGF18 | fibroblast growth factor 18 |
| FST | follistatin |
| GJA4 | gap junction protein, alpha 4, 37kDa |
| GK | glycerol kinase |
| GNAT2 | guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2 |
| GNL3L | guanine nucleotide binding protein-like 3 (nucleolar)-like |
| GRM6 | glutamate receptor, metabotropic 6 |
| HAO2 | hydroxyacid oxidase 2 (long chain) |
| HEG1 | heart development protein with EGF-like domains 1 |
| HFE | hemochromatosis |
| HNRNPM | heterogeneous nuclear ribonucleoprotein M |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 |
| HSPB6 | heat shock protein, alpha-crystallin-related, B6 |
| IDI2-AS1 | IDI2 antisense RNA 1 |
| ITGB3 | integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) |
| JAK2 | Janus kinase 2 |
| KDM4B | lysine (K)-specific demethylase 4B |
| KLF12 | Kruppel-like factor 12 |
| LAMA4 | laminin, alpha 4 |
| LDLRAD4 | low density lipoprotein receptor class A domain containing 4 |
| MAP2K7 | mitogen-activated protein kinase kinase 7 |
| MYH14 | myosin, heavy chain 14, non-muscle |
| MYOF | myoferlin |
| NFKBIB | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta |
| NPY1R | neuropeptide Y receptor Y1 |
| NPY4R | neuropeptide Y receptor Y4 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 |
| OMG | oligodendrocyte myelin glycoprotein |
| PARD6B | par-6 family cell polarity regulator beta |
| PDGFB | platelet-derived growth factor beta polypeptide |
| PDZK1 | PDZ domain containing 1 |
| PGR | progesterone receptor |
| PIP | prolactin-induced protein |
| PLK4 | polo-like kinase 4 |
| PML | promyelocytic leukemia |
| PMS2P3 | postmeiotic segregation increased 2 pseudogene 3 |
| PODNL1 | podocan-like 1 |
| POFUT1 | protein O-fucosyltransferase 1 |
| PPP2R2B | protein phosphatase 2, regulatory subunit B, beta |
| PRLR | prolactin receptor |
| RAB35 | RAB35, member RAS oncogene family |
| RASA3 | RAS p21 protein activator 3 |
| RND1 | Rho family GTPase 1 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 |
| RRBP1 | ribosome binding protein 1 |
| RSPH14 | radial spoke head 14 homolog (Chlamydomonas) |
| RUNDC3A | RUN domain containing 3A |
| SAG | S-antigen; retina and pineal gland (arrestin) |
| SERHL2 | serine hydrolase-like 2 |
| SIGLEC7 | sialic acid binding Ig-like lectin 7 |
| SLC24A1 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 1 |
| SLC39A9 | solute carrier family 39, member 9 |
| SLC9A3R2 | solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) |
| SRSF5 | serine/arginine-rich splicing factor 5 |
| STMN1 | stathmin 1 |
| STRN | striatin, calmodulin binding protein |
| SUGP1 | SURP and G patch domain containing 1 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 |
| TRIM10 | tripartite motif containing 10 |
| TRIM68 | tripartite motif containing 68 |
| VAMP5 | vesicle-associated membrane protein 5 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) |
| WDR55 | WD repeat domain 55 |
| WDTC1 | WD and tetratricopeptide repeats 1 |
| ZFP37 | ZFP37 zinc finger protein |
| ZNF480 | zinc finger protein 480 |
| ZNF589 | zinc finger protein 589 |
| Symbol | Name |
|---|---|
| ACSF2 | acyl-CoA synthetase family member 2 |
| ADGRE5 | adhesion G protein-coupled receptor E5 |
| ALDH1A3 | aldehyde dehydrogenase 1 family, member A3 |
| BAHCC1 | BAH domain and coiled-coil containing 1 |
| BBS7 | Bardet-Biedl syndrome 7 |
| C10ORF88 | chromosome 10 open reading frame 88 |
| C14ORF93 | chromosome 14 open reading frame 93 |
| C19ORF73 | chromosome 19 open reading frame 73 |
| C2ORF54 | chromosome 2 open reading frame 54 |
| CCDC25 | coiled-coil domain containing 25 |
| CCDC69 | coiled-coil domain containing 69 |
| CCDC85C | coiled-coil domain containing 85C |
| CCNK | cyclin K |
| CHRM3 | cholinergic receptor, muscarinic 3 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 |
| CIC | capicua transcriptional repressor |
| CRIP1 | cysteine-rich protein 1 (intestinal) |
| CUL9 | cullin 9 |
| DDIT3 | DNA-damage-inducible transcript 3 |
| DGCR11 | DiGeorge syndrome critical region gene 11 (non-protein coding) |
| DNM1 | dynamin 1 |
| EFNA1 | ephrin-A1 |
| EPHA2 | EPH receptor A2 |
| EPHA4 | EPH receptor A4 |
| ERMAP | erythroblast membrane-associated protein (Scianna blood group) |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| EXOC6B | exocyst complex component 6B |
| FANCC | Fanconi anemia, complementation group C |
| FER | fer (fps/fes related) tyrosine kinase |
| FLCN | folliculin |
| FOXI1 | forkhead box I1 |
| GNG13 | guanine nucleotide binding protein (G protein), gamma 13 |
| GTF2H3 | general transcription factor IIH, polypeptide 3, 34kDa |
| HCAR3 | hydroxycarboxylic acid receptor 3 |
| HDAC5 | histone deacetylase 5 |
| HDAC7 | histone deacetylase 7 |
| HIST1H1D | histone cluster 1, H1d |
| HIST1H4D | histone cluster 1, H4d |
| HOXA4 | homeobox A4 |
| HOXC8 | homeobox C8 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon |
| IKZF5 | IKAROS family zinc finger 5 (Pegasus) |
| IL1RAPL2 | interleukin 1 receptor accessory protein-like 2 |
| JUNB | jun B proto-oncogene |
| KBTBD11 | kelch repeat and BTB (POZ) domain containing 11 |
| KCNN4 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) |
| LAMP3 | lysosomal-associated membrane protein 3 |
| LZTS3 | leucine zipper, putative tumor suppressor family member 3 |
| MAP1S | microtubule-associated protein 1S |
| MAST3 | microtubule associated serine/threonine kinase 3 |
| MYOZ3 | myozenin 3 |
| N4BP3 | NEDD4 binding protein 3 |
| NCALD | neurocalcin delta |
| NEK11 | NIMA-related kinase 11 |
| NFKBIL1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 |
| NPFFR1 | neuropeptide FF receptor 1 |
| ORAI3 | ORAI calcium release-activated calcium modulator 3 |
| PCDHB3 | protocadherin beta 3 |
| PIM2 | Pim-2 proto-oncogene, serine/threonine kinase |
| PLA2G4C | phospholipase A2, group IVC (cytosolic, calcium-independent) |
| PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) |
| PLCD1 | phospholipase C, delta 1 |
| PLEKHO2 | pleckstrin homology domain containing, family O member 2 |
| PLOD3 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3 |
| PRR15L | proline rich 15-like |
| QPCTL | glutaminyl-peptide cyclotransferase-like |
| RAB5B | RAB5B, member RAS oncogene family |
| RIN2 | Ras and Rab interactor 2 |
| RNF208 | ring finger protein 208 |
| RNF43 | ring finger protein 43 |
| SCGB2A2 | secretoglobin, family 2A, member 2 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 |
| SERPINF1 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 |
| SGCG | sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein) |
| SKI | SKI proto-oncogene |
| SLC12A6 | solute carrier family 12 (potassium/chloride transporter), member 6 |
| SLC25A23 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23 |
| SLC35C1 | solute carrier family 35 (GDP-fucose transporter), member C1 |
| SLC4A2 | solute carrier family 4 (anion exchanger), member 2 |
| SLC4A8 | solute carrier family 4, sodium bicarbonate cotransporter, member 8 |
| SLC8B1 | solute carrier family 8 (sodium/lithium/calcium exchanger), member B1 |
| TBC1D2 | TBC1 domain family, member 2 |
| TDRD1 | tudor domain containing 1 |
| TFAP4 | transcription factor AP-4 (activating enhancer binding protein 4) |
| THRAP3 | thyroid hormone receptor associated protein 3 |
| TNRC6B | trinucleotide repeat containing 6B |
| UBQLN4 | ubiquilin 4 |
| USP19 | ubiquitin specific peptidase 19 |
| VIPR1 | vasoactive intestinal peptide receptor 1 |
| WDR19 | WD repeat domain 19 |
| WDR25 | WD repeat domain 25 |
| WDR91 | WD repeat domain 91 |
| WWC3 | WWC family member 3 |
| ZFHX2 | zinc finger homeobox 2 |
| ZNF358 | zinc finger protein 358 |
| ZNF696 | zinc finger protein 696 |
| ZSCAN2 | zinc finger and SCAN domain containing 2 |
| ZSCAN9 | zinc finger and SCAN domain containing 9 |
| ZSWIM1 | zinc finger, SWIM-type containing 1 |
