| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the spectinomycin-4773 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| A2M | alpha-2-macroglobulin |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 |
| ADAM18 | ADAM metallopeptidase domain 18 |
| ALDOAP2 | aldolase A, fructose-bisphosphate pseudogene 2 |
| ALDOB | aldolase B, fructose-bisphosphate |
| ANPEP | alanyl (membrane) aminopeptidase |
| ATP1A2 | ATPase, Na+/K+ transporting, alpha 2 polypeptide |
| AURKA | aurora kinase A |
| B3GNT4 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4 |
| BMP2K | BMP2 inducible kinase |
| BTN3A1 | butyrophilin, subfamily 3, member A1 |
| CA9 | carbonic anhydrase IX |
| CACNG1 | calcium channel, voltage-dependent, gamma subunit 1 |
| CBX8 | chromobox homolog 8 |
| CDC14B | cell division cycle 14B |
| CLDN17 | claudin 17 |
| CLEC1A | C-type lectin domain family 1, member A |
| CNKSR2 | connector enhancer of kinase suppressor of Ras 2 |
| CNPY4 | canopy FGF signaling regulator 4 |
| COL11A1 | collagen, type XI, alpha 1 |
| COL1A1 | collagen, type I, alpha 1 |
| COX6A2 | cytochrome c oxidase subunit VIa polypeptide 2 |
| CSHL1 | chorionic somatomammotropin hormone-like 1 |
| CXCR6 | chemokine (C-X-C motif) receptor 6 |
| DAPK3 | death-associated protein kinase 3 |
| DFNB31 | deafness, autosomal recessive 31 |
| DOK1 | docking protein 1, 62kDa (downstream of tyrosine kinase 1) |
| EFNA3 | ephrin-A3 |
| EFS | embryonal Fyn-associated substrate |
| EPB41L3 | erythrocyte membrane protein band 4.1-like 3 |
| EXOC7 | exocyst complex component 7 |
| FAAH | fatty acid amide hydrolase |
| FADS2 | fatty acid desaturase 2 |
| FER | fer (fps/fes related) tyrosine kinase |
| FOSL2 | FOS-like antigen 2 |
| FRMPD1 | FERM and PDZ domain containing 1 |
| GPR143 | G protein-coupled receptor 143 |
| GRM1 | glutamate receptor, metabotropic 1 |
| GSPT2 | G1 to S phase transition 2 |
| HIST1H2BN | histone cluster 1, H2bn |
| HNRNPA3P1 | heterogeneous nuclear ribonucleoprotein A3 pseudogene 1 |
| HOXA4 | homeobox A4 |
| ICAM4 | intercellular adhesion molecule 4 (Landsteiner-Wiener blood group) |
| IFFO1 | intermediate filament family orphan 1 |
| IFT27 | intraflagellar transport 27 |
| IGLV3-19 | immunoglobulin lambda variable 3-19 |
| IKZF4 | IKAROS family zinc finger 4 (Eos) |
| KCNJ8 | potassium channel, inwardly rectifying subfamily J, member 8 |
| KDM4B | lysine (K)-specific demethylase 4B |
| KHDRBS2 | KH domain containing, RNA binding, signal transduction associated 2 |
| LDLRAD4 | low density lipoprotein receptor class A domain containing 4 |
| LIMS2 | LIM and senescent cell antigen-like domains 2 |
| LRCH4 | leucine-rich repeats and calponin homology (CH) domain containing 4 |
| MAPK7 | mitogen-activated protein kinase 7 |
| MED31 | mediator complex subunit 31 |
| MKL1 | megakaryoblastic leukemia (translocation) 1 |
| NBL1 | neuroblastoma 1, DAN family BMP antagonist |
| NFKBIB | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta |
| NOS1AP | nitric oxide synthase 1 (neuronal) adaptor protein |
| NXPH3 | neurexophilin 3 |
| OTOF | otoferlin |
| PAIP2B | poly(A) binding protein interacting protein 2B |
| PARP3 | poly (ADP-ribose) polymerase family, member 3 |
| PBOV1 | prostate and breast cancer overexpressed 1 |
| PBRM1 | polybromo 1 |
| PEX3 | peroxisomal biogenesis factor 3 |
| PHYHIP | phytanoyl-CoA 2-hydroxylase interacting protein |
| PIGC | phosphatidylinositol glycan anchor biosynthesis, class C |
| PIP5K1A | phosphatidylinositol-4-phosphate 5-kinase, type I, alpha |
| PLEKHF1 | pleckstrin homology domain containing, family F (with FYVE domain) member 1 |
| PLEKHG3 | pleckstrin homology domain containing, family G (with RhoGef domain) member 3 |
| PLEKHO2 | pleckstrin homology domain containing, family O member 2 |
| PLTP | phospholipid transfer protein |
| PML | promyelocytic leukemia |
| POU3F4 | POU class 3 homeobox 4 |
| PTGER3 | prostaglandin E receptor 3 (subtype EP3) |
| RAC2 | ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) |
| RIMBP2 | RIMS binding protein 2 |
| RUNX1 | runt-related transcription factor 1 |
| S100A3 | S100 calcium binding protein A3 |
| SCARB1 | scavenger receptor class B, member 1 |
| SCG2 | secretogranin II |
| SCN10A | sodium channel, voltage gated, type X alpha subunit |
| SDHB | succinate dehydrogenase complex, subunit B, iron sulfur (Ip) |
| SLAMF7 | SLAM family member 7 |
| SLC12A4 | solute carrier family 12 (potassium/chloride transporter), member 4 |
| SLC5A4 | solute carrier family 5 (glucose activated ion channel), member 4 |
| SYDE1 | synapse defective 1, Rho GTPase, homolog 1 (C. elegans) |
| TAL1 | T-cell acute lymphocytic leukemia 1 |
| TCEB3B | transcription elongation factor B polypeptide 3B (elongin A2) |
| TCF12 | transcription factor 12 |
| TMPRSS4 | transmembrane protease, serine 4 |
| TSC22D4 | TSC22 domain family, member 4 |
| TUBA4B | tubulin, alpha 4b |
| UPK3B | uroplakin 3B |
| VAMP2 | vesicle-associated membrane protein 2 (synaptobrevin 2) |
| VWA5A | von Willebrand factor A domain containing 5A |
| ZNF358 | zinc finger protein 358 |
| ZNF407 | zinc finger protein 407 |
| Symbol | Name |
|---|---|
| ABCC6 | ATP-binding cassette, sub-family C (CFTR/MRP), member 6 |
| ACTR8 | ARP8 actin-related protein 8 homolog (yeast) |
| ADORA2B | adenosine A2b receptor |
| ARHGAP12 | Rho GTPase activating protein 12 |
| ARRB2 | arrestin, beta 2 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 |
| ASB9 | ankyrin repeat and SOCS box containing 9 |
| ATP8B1 | ATPase, aminophospholipid transporter, class I, type 8B, member 1 |
| BBC3 | BCL2 binding component 3 |
| BCL2L2 | BCL2-like 2 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 |
| BSG | basigin (Ok blood group) |
| C1ORF56 | chromosome 1 open reading frame 56 |
| CBX4 | chromobox homolog 4 |
| CCNL1 | cyclin L1 |
| CDKL3 | cyclin-dependent kinase-like 3 |
| CLK1 | CDC-like kinase 1 |
| DNAJC17 | DnaJ (Hsp40) homolog, subfamily C, member 17 |
| EIF2S3 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa |
| EVPL | envoplakin |
| FGD6 | FYVE, RhoGEF and PH domain containing 6 |
| FMO4 | flavin containing monooxygenase 4 |
| FUZ | fuzzy planar cell polarity protein |
| GALNT14 | polypeptide N-acetylgalactosaminyltransferase 14 |
| GATC | glutamyl-tRNA(Gln) amidotransferase, subunit C |
| GINS4 | GINS complex subunit 4 (Sld5 homolog) |
| GLB1L2 | galactosidase, beta 1-like 2 |
| GLTP | glycolipid transfer protein |
| GPHN | gephyrin |
| GPR87 | G protein-coupled receptor 87 |
| GTF2H3 | general transcription factor IIH, polypeptide 3, 34kDa |
| HAUS6 | HAUS augmin-like complex, subunit 6 |
| HIST1H1D | histone cluster 1, H1d |
| HIST1H2AJ | histone cluster 1, H2aj |
| HIST1H4D | histone cluster 1, H4d |
| IL4R | interleukin 4 receptor |
| INPP5K | inositol polyphosphate-5-phosphatase K |
| IREB2 | iron-responsive element binding protein 2 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) |
| KDELR1 | KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) |
| LMNB1 | lamin B1 |
| MANBA | mannosidase, beta A, lysosomal |
| MUM1 | melanoma associated antigen (mutated) 1 |
| MYO1E | myosin IE |
| NME6 | NME/NM23 nucleoside diphosphate kinase 6 |
| NR1D2 | nuclear receptor subfamily 1, group D, member 2 |
| NUP62CL | nucleoporin 62kDa C-terminal like |
| OR7E156P | olfactory receptor, family 7, subfamily E, member 156 pseudogene |
| P2RX4 | purinergic receptor P2X, ligand gated ion channel, 4 |
| PEX26 | peroxisomal biogenesis factor 26 |
| PHACTR4 | phosphatase and actin regulator 4 |
| PIGB | phosphatidylinositol glycan anchor biosynthesis, class B |
| PIK3CA | phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha |
| POLR1B | polymerase (RNA) I polypeptide B, 128kDa |
| PPT2 | palmitoyl-protein thioesterase 2 |
| PRODH | proline dehydrogenase (oxidase) 1 |
| PSENEN | presenilin enhancer gamma secretase subunit |
| RANGRF | RAN guanine nucleotide release factor |
| RARS | arginyl-tRNA synthetase |
| REEP4 | receptor accessory protein 4 |
| RFWD3 | ring finger and WD repeat domain 3 |
| RFX7 | regulatory factor X, 7 |
| RINT1 | RAD50 interactor 1 |
| RMND1 | required for meiotic nuclear division 1 homolog (S. cerevisiae) |
| SECISBP2 | SECIS binding protein 2 |
| SETD6 | SET domain containing 6 |
| SH3GLB2 | SH3-domain GRB2-like endophilin B2 |
| SHCBP1 | SHC SH2-domain binding protein 1 |
| SIDT1 | SID1 transmembrane family, member 1 |
| SLC26A2 | solute carrier family 26 (anion exchanger), member 2 |
| SLC8B1 | solute carrier family 8 (sodium/lithium/calcium exchanger), member B1 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase |
| SNORA21 | small nucleolar RNA, H/ACA box 21 |
| SPAG1 | sperm associated antigen 1 |
| SPIDR | scaffolding protein involved in DNA repair |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 |
| TAF12 | TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 20kDa |
| TMEM159 | transmembrane protein 159 |
| TMEM230 | transmembrane protein 230 |
| TPTE | transmembrane phosphatase with tensin homology |
| TRMU | tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase |
| UBXN8 | UBX domain protein 8 |
| USP27X | ubiquitin specific peptidase 27, X-linked |
| XYLT2 | xylosyltransferase II |
| YIPF5 | Yip1 domain family, member 5 |
| ZFP30 | ZFP30 zinc finger protein |
| ZKSCAN3 | zinc finger with KRAB and SCAN domains 3 |
| ZNF12 | zinc finger protein 12 |
| ZNF124 | zinc finger protein 124 |
| ZNF254 | zinc finger protein 254 |
| ZNF430 | zinc finger protein 430 |
| ZNF562 | zinc finger protein 562 |
| ZNF652 | zinc finger protein 652 |
| ZNF7 | zinc finger protein 7 |
| ZNF721 | zinc finger protein 721 |
