spectrin binding Gene Set
Dataset
GO Molecular Function Annotations 2015
Category
structural or functional annotations
Type
molecular function
Description
Interacting selectively and non-covalently with spectrin, a protein that is the major constituent of the erythrocyte cytoskeletal network. It associates with band 4.1 (see band protein) and actin to form the cytoskeletal superstructure of the erythrocyte plasma membrane. It is composed of nonhomologous chains, alpha and beta, which aggregate side-to-side in an antiparallel fashion to form dimers, tetramers, and higher polymers. (Gene Ontology , GO_0030507 )
External Link
http://amigo.geneontology.org/amigo/term/GO:0030507
Similar Terms
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Genes
25 genes performing the spectrin binding molecular function from the curated GO Molecular Function Annotations 2015 dataset.
Symbol
Name
ADD1
adducin 1 (alpha)
ADD2
adducin 2 (beta)
ANK1
ankyrin 1, erythrocytic
ANK2
ankyrin 2, neuronal
ANK3
ankyrin 3, node of Ranvier (ankyrin G)
CAMSAP1
calmodulin regulated spectrin-associated protein 1
DCTN2
dynactin 2 (p50)
DMTN
dematin actin binding protein
DYNC1I1
dynein, cytoplasmic 1, intermediate chain 1
EPB41
erythrocyte membrane protein band 4.1
GNB1
guanine nucleotide binding protein (G protein), beta polypeptide 1
GNB3
guanine nucleotide binding protein (G protein), beta polypeptide 3
KIF3A
kinesin family member 3A
MYO10
myosin X
MYO7A
myosin VIIA
NPHS1
nephrosis 1, congenital, Finnish type (nephrin)
PDE6G
phosphodiesterase 6G, cGMP-specific, rod, gamma
PTPRN
protein tyrosine phosphatase, receptor type, N
RHO
rhodopsin
SLC26A5
solute carrier family 26 (anion exchanger), member 5
SPTAN1
spectrin, alpha, non-erythrocytic 1
SPTBN4
spectrin, beta, non-erythrocytic 4
SPTBN5
spectrin, beta, non-erythrocytic 5
USH1C
Usher syndrome 1C (autosomal recessive, severe)
USH1G
Usher syndrome 1G (autosomal recessive)
