Membrane associated dimeric protein (240 and 220 kDa) of erythrocytes. Forms a complex with ankyrin, actin and probably other components of the membrane cytoskeleton, so that there is a mesh of proteins underlying the plasma membrane, potentially restricting the lateral mobility of integral proteins. (Gene Ontology, GO_0008091)
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9 proteins localized to the spectrin cellular component from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset.