sperm-egg recognition Gene Set

Dataset GO Biological Process Annotations 2025
Category structural or functional annotations
Type biological process
Description The initial contact step made between the sperm plasma membrane and outer layer of the egg during fertilization. (Gene Ontology, GO_0035036)
External Link http://amigo.geneontology.org/amigo/term/GO:0035036
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Genes

33 genes participating in the sperm-egg recognition biological process from the curated GO Biological Process Annotations 2025 dataset.

Symbol Name
ADAM18 ADAM metallopeptidase domain 18
ADAM2 ADAM metallopeptidase domain 2
ADAM32 ADAM metallopeptidase domain 32
CD9 CD9 molecule
CRISP1 cysteine-rich secretory protein 1
DCST1 DC-STAMP domain containing 1
DCST2 DC-STAMP domain containing 2
FETUB fetuin B
FOLR2 folate receptor 2 (fetal)
FOLR3 folate receptor 3 (gamma)
FREY1 Frey regulator of sperm-oocyte fusion 1
IZUMO1 izumo sperm-egg fusion 1
IZUMO1R IZUMO1 receptor, JUNO
LOC112694756 uncharaterized LOC112694756
LY6K lymphocyte antigen 6 complex, locus K
PCSK4 proprotein convertase subtilisin/kexin type 4
PRSS37 protease, serine, 37
PRSS55 protease, serine, 55
SPACA4 sperm acrosome associated 4
SPACA6 sperm acrosome associated 6
SPAM1 sperm adhesion molecule 1 (PH-20 hyaluronidase, zona pellucida binding)
SPESP1 sperm equatorial segment protein 1
SPPL2C signal peptide peptidase like 2C
TEX101 testis expressed 101
TMEM81 transmembrane protein 81
UBAP2L ubiquitin associated protein 2-like
VDAC2 voltage-dependent anion channel 2
ZAN zonadhesin (gene/pseudogene)
ZP2 zona pellucida glycoprotein 2 (sperm receptor)
ZP3 zona pellucida glycoprotein 3 (sperm receptor)
ZP4 zona pellucida glycoprotein 4
ZPBP zona pellucida binding protein
ZPBP2 zona pellucida binding protein 2