spermidine Gene Set

Dataset LINCS L1000 CMAP Chemical Perturbation Consensus Signatures
Category transcriptomics
Type small molecule perturbation
Description A triamine that is the 1,5,10-triaza derivative of decane. (Chemical Entities of Biological Interest Ontology, CHEBI_16610)
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Genes

8 genes differentially expressed following the spermidine small molecule perturbation from the LINCS L1000 CMAP Chemical Perturbation Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
DFFB DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase) 4.32521
MTA1 metastasis associated 1 3.39966
GP5 glycoprotein V (platelet) 3.14391
MYO7B myosin VIIB 3.04284

decreased expression

Symbol Name Standardized Value
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase -6.57317
UBQLN2 ubiquilin 2 -3.22035
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -3.21362
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila) -3.01649